(2R,4R)-2,4-diazidopentane | 798568-75-9

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: (2R,4R)-2,4-diazidopentane
• CAS: 798568-75-9
• 化学式: C₅H₁₀N₆
• 分子量: 154.175
• InChiKey: AWJFANPWIBNSDY-RFZPGFLSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  28.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  二氯苯酚溴酯 、 (2R,4R)-2,4-diazidopentane 在 sodium hydroxide 作用下， 生成 N,N-diphenyl-(2R,4R)-pentanediamine
  参考文献：
  名称：

  Asymmetric Coordination Polymerization of Acrylamides by Enantiomeric Metallocenium Ester Enolate Catalysts

  摘要：

  Optically active, rigid one-handed helical poly(N,N-diaryl acrylamide)s and their copolymers with the randomly coiled methacrylate blocks were synthesized using the asymmetric coordination polymerization rendered by enantiomeric ansa-zirconocenium ester enolate catalysts under ambient conditions.

  DOI：

  10.1021/ja072073p
• 作为产物：
  描述：

  Trifluoro-methanesulfonic acid (1S,3S)-1-methyl-3-trifluoromethanesulfonyloxy-butyl ester 在 [(Me₂N)2CNH₂][N₃] 作用下， 生成 (2R,4R)-2,4-diazidopentane
  参考文献：
  名称：

  Asymmetric Coordination Polymerization of Acrylamides by Enantiomeric Metallocenium Ester Enolate Catalysts

  摘要：

  Optically active, rigid one-handed helical poly(N,N-diaryl acrylamide)s and their copolymers with the randomly coiled methacrylate blocks were synthesized using the asymmetric coordination polymerization rendered by enantiomeric ansa-zirconocenium ester enolate catalysts under ambient conditions.

  DOI：

  10.1021/ja072073p

文献信息

• Enantioselective Synthesis of <i>ansa</i>-Zirconocenes
  作者：Matthew D. LoCoco、Richard F. Jordan

  DOI：10.1021/ja045245g

  日期：2004.11.1

  The reaction of the chiral chelated bis-amide complex Zr(2R,4R)-PhNCHMeCH2CHMeNPh}Cl2(THF)2 (R,R-7) with lithium ansa-bis-indenyl reagents Li2[SBI](Et2O) (8a, SBI = (1-indenyl)2SiMe2) or Li2[EBI](Et2O) (8b, EBI = 1,2-(1-indenyl)2ethane) in THF affords the corresponding ansa-zirconocenes S,S-(SBI)Zr(2R,4R)-PhNCHMeCH2CHMeNPh} (S,S,R,R-9a) or S,S-(EBI)Zr(2R,4R)-PhNCHMeCH2CHMeNPh} (S,S,R,R-9b) in >95% isolated yield and >99% enantiomeric excess. Compound 9b was converted to the corresponding enantiomerically pure dichloride S,S-(EBI)ZrCl2 (S,S-10b) in 91% isolated yield by reaction with HCl in Et2O. The chiral diamine (2R,4R)-HPhNCHMeCH2CHMeNHPh (R,R-5) was recovered from this reaction.
• Asymmetric Coordination Polymerization of Acrylamides by Enantiomeric Metallocenium Ester Enolate Catalysts
  作者：Garret M. Miyake、Wesley R. Mariott、Eugene Y.-X. Chen

  DOI：10.1021/ja072073p

  日期：2007.5.1

  Optically active, rigid one-handed helical poly(N,N-diaryl acrylamide)s and their copolymers with the randomly coiled methacrylate blocks were synthesized using the asymmetric coordination polymerization rendered by enantiomeric ansa-zirconocenium ester enolate catalysts under ambient conditions.