4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyldiphenylphosphinate | 1262219-78-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyldiphenylphosphinate
• 英文别名: Tert-butyl-(4-diphenylphosphoryloxycyclohexyl)oxy-dimethylsilane
• CAS: 1262219-78-2
• 化学式: C₂₄H₃₅O₃PSi
• 分子量: 430.599
• InChiKey: WBVKNYASJCATDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.27
• 重原子数：
  29
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyldiphenylphosphinate 在 NBu₄BF₄ 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以90%的产率得到1-(tert-butyldimethylsiloxy)cyclohexane
  参考文献：
  名称：

  Novel Electrochemical Deoxygenation Reaction Using Diphenylphosphinates

  摘要：

  The electrochemical reduction of diphenylphosphinate esters leads smoothly and in high yields to the corresponding deoxygenated products. In comparison with the previously developed methodologies, the electrolysis could be performed at lower temperature and with a higher current density, resulting in a shorter reaction time.

  DOI：

  10.1021/ol102714s
• 作为产物：
  描述：

  1,4-环己二醇 在 咪唑 作用下， 以 乙醚 、 二氯甲烷 为溶剂， 反应 2.0h， 生成 4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyldiphenylphosphinate
  参考文献：
  名称：

  Novel Electrochemical Deoxygenation Reaction Using Diphenylphosphinates

  摘要：

  The electrochemical reduction of diphenylphosphinate esters leads smoothly and in high yields to the corresponding deoxygenated products. In comparison with the previously developed methodologies, the electrolysis could be performed at lower temperature and with a higher current density, resulting in a shorter reaction time.

  DOI：

  10.1021/ol102714s

文献信息

• Novel Electrochemical Deoxygenation Reaction Using Diphenylphosphinates
  作者：Kevin Lam、István E. Markó

  DOI：10.1021/ol102714s

  日期：2011.2.4

  The electrochemical reduction of diphenylphosphinate esters leads smoothly and in high yields to the corresponding deoxygenated products. In comparison with the previously developed methodologies, the electrolysis could be performed at lower temperature and with a higher current density, resulting in a shorter reaction time.