1-(1H-benzo[d][1,2,3]triazol-1-yl)hexan-1-one | 331672-94-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并三唑类
• 英文名称: 1-(1H-benzo[d][1,2,3]triazol-1-yl)hexan-1-one
• 英文别名: 1-(benzotriazol-1-yl)hexan-1-one
• CAS: 331672-94-7
• 化学式: C₁₂H₁₅N₃O
• 分子量: 217.271
• InChiKey: GMGRODQXAQKKRE-UHFFFAOYSA-N

物化性质

• 沸点：
  352.6±25.0 °C(Predicted)
• 密度：
  1.17±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  47.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-甲基乙酰乙酸乙酯 、 1-(1H-benzo[d][1,2,3]triazol-1-yl)hexan-1-one 在 sodium hydride 、 ammonium hydroxide 、 氯化铵 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 15.67h， 以52%的产率得到ethyl 2-methyl-3-oxooctanoate
  参考文献：
  名称：

  1-乙酰基苯并三唑通过乙酰乙酸酯和乙酰酮的C-酰化/脱乙酰作用制备β-酮酯和β-二酮

  摘要：

  酰基，芳酰基和杂芳基乙酸酯6a - f和8a - 1通过在氢化钠存在下1-酰基苯并三唑1a - k与乙酰乙酸酯5或7a，b反应，然后进行区域选择性脱乙酰反应制得。乙酰丙酮和苯甲酰丙酮的类似的C-酰化/脱乙酰基分别提供β-二酮10a - d和13a - c。

  DOI：

  10.1021/jo049274l
• 作为产物：
  描述：

  T406石油添加剂 在 TEA 作用下， 生成 1-(1H-benzo[d][1,2,3]triazol-1-yl)hexan-1-one
  参考文献：
  名称：

  Solid-phase preparation of amides using N-acylbenzotriazoles

  摘要：

  Wang resin linked amines were efficiently converted into amides using acylbenzotriazoles. Cleavage of resins gave the desired amides 7Aa-Gf in 30-99% yields with good to excellent purities. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(02)00278-0

文献信息

• Acyloxyphosphonium versus Aminophosphonium Intermediates: Application to the Synthesis of<i>N</i>-Acylbenzotriazoles
  作者：Chuthamat Duangkamol、Sirilak Wangngae、Mookda Pattarawarapan、Wong Phakhodee

  DOI：10.1002/ejoc.201403076

  日期：2014.11

  outcome of the reaction is reversed from no reaction to almost quantitative yield of the expected product simply by switching the order of the addition of the reagents to the presumed acyloxyphosphonium intermediate. If triethylamine was present before treatment with 1H-benzotriazole, anhydride was always exclusively generated without a detectable amount of the expected product. However, if the base

  在尝试通过使用 Ph3P/I2 作为酸活化系统将羧酸直接转化为 N-酰基苯并三唑时，反应的结果从没有反应逆转为几乎定量的预期产物产率，只需改变加入的顺序即可假定的酰氧基磷中间体的试剂。如果在用 1H-苯并三唑处理之前存在三乙胺，则总是仅生成酸酐而没有可检测量的预期产物。然而，如果在加入 1H-苯并三唑后使用碱，则反应顺利进行，在较短的反应时间内以良好至极好的产率得到 N-酰基苯并三唑。
• Facile synthesis of N-acylbenzotriazoles from carboxylic acids mediated by 2,4,6-trichloro-1,3,5-triazine and triethylamine
  作者：Sirawit Wet-osot、Chuthamat Duangkamol、Mookda Pattarawarapan、Wong Phakhodee

  DOI：10.1007/s00706-014-1408-1

  日期：2015.6

  AbstractA facile, efficient, and economic method toward N-acylbenzotriazoles was reported using 2,4,6-trichloro-1,3,5-triazine in combination with triethylamine as a carboxylic acid activator. Through reacting 1H-benzotriazole with the generated triacylated triazine intermediate, a series of N-acylbenzotriazoles could be rapidly prepared in high yields without column chromatography. Graphical abstract

  摘要据报道，使用2,4,6-三氯-1,3,5-三嗪结合三乙胺作为羧酸活化剂，可轻松，高效且经济地制得N-酰基苯并三唑。通过使1 H-苯并三唑与生成的三酰基化三嗪中间体反应，无需柱色谱法即可快速高收率地制备一系列N-酰基苯并三唑。 图形概要
• COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS
  申请人：Wagner Barbara

  公开号：US20100330009A1

  公开（公告）日：2010-12-30

  The present invention relates to derivatives of the 1H-pyrano[4,3-b]benzofuran-1-one structure and their nitrogen analogues which possess powerful antioxidant properties combined with a highly effective UV absorbing functionality in one molecule. These compounds are especially useful in cosmetical and dermatological formulations.

  本发明涉及1H-吡喴并[4,3-b]苯并呋喃-1-酮结构及其氮类似物的衍生物，这些衍生物具有强大的抗氧化性能，同时结合了高效的吸收紫外线功能在一个分子中。这些化合物在化妆品和皮肤科配方中特别有用。
• METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM
  申请人：Toyo Ink Mfg. Co., Ltd

  公开号：EP1952918A1

  公开（公告）日：2008-08-06

  Disclosed is a method for producing a metal particle dispersion wherein a metal compound is reduced by using carbodihydrazide represented by the formula (1) below or a polybasic acid polyhydrazide represented by the formula (2) below (wherein R represents an n-valent polybasic acid residue) in a liquid medium. By reducing the metal compound in the presence of a compound having a function preventing discoloration of the metal, there can be obtained a metal particle dispersion having excellent discoloration preventing properties. Metal particles produced by such methods have a uniform particle diameter and are excellent in dispersion stability. By using a conductive resin composition or conductive ink containing a metal particle dispersion obtained by such production methods, there can be formed a conductive coating film, such as a conductive circuit or an electromagnetic layer, having good characteristics.

  本发明公开了一种生产金属颗粒分散液的方法，该方法通过在液体介质中使用下式 (1) 所代表的碳二酰肼或下式 (2) 所代表的多基酸多酰肼（其中 R 代表正价多基酸残基）还原金属化合物。通过在具有防止金属褪色功能的化合物存在下还原金属化合物，可获得具有优异防褪色性能的金属颗粒分散液。通过这种方法制得的金属颗粒具有均匀的颗粒直径和出色的分散稳定性。使用含有通过这种生产方法获得的金属颗粒分散体的导电树脂组合物或导电墨水，可以形成具有良好特性的导电涂膜，例如导电电路或电磁层。
• COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION COMPRISING SAID COLORED METALLIC PIGMENT
  申请人：TOYO ALUMINIUM KABUSHIKI KAISHA

  公开号：EP1990377A1

  公开（公告）日：2008-11-12

  This invention provides a colored metallic pigment, which can develop a variety of colors and varied interference colors while maintaining good lightfastness, weatherfastness and hiding power, a process for producing the same, a coating composition containing the colored metallic pigment and capable of providing a coating film having excellent finished appearance, and a cosmetic preparation containing the colored metallic pigment, having excellent hiding power, and capable of providing sharp hue. The colored metallic pigment comprises at least a metallic pigment, an amorphous silicon oxide film layer provided on the surface of the metallic pigment, a metal layer provided on the surface of the amorphous silicon oxide film layer, and metallic particles provided on the surface of the metal layer. The metallic particles are provided so as to directly cover a part of the surface of the metal layer. In the colored metallic pigment, the metal layer preferably comprises at least one metal selected from Sn, Pd, Pt and Au. The metallic particle preferably comprises at least one metal selected from Cu, Ni and Ag.

  本发明提供了一种彩色金属颜料，它能在保持良好的耐光性、耐候性和遮盖力的同时，显现出多种颜色和各种干扰色；还提供了一种生产彩色金属颜料的工艺；一种含有该彩色金属颜料并能提供具有良好成品外观的涂膜的涂料组合物；以及一种含有该彩色金属颜料、具有良好遮盖力并能提供鲜明色调的化妆品制剂。彩色金属颜料至少包括金属颜料、设置在金属颜料表面的非晶氧化硅薄膜层、设置在非晶氧化硅薄膜层表面的金属层以及设置在金属层表面的金属颗粒。金属颗粒的设置是为了直接覆盖金属层的部分表面。在有色金属颜料中，金属层最好包括至少一种选自 Sn、Pd、Pt 和 Au 的金属。金属颗粒最好包括至少一种选自铜、镍和银的金属。