A variety of substituted quinoline/pyridine, thiochromene and naphthalene derivatives, which might be of biological and medicinal value, were synthesized by copper‐catalyzed domino SN2′/coupling, SN2′/deacylation/coupling and SN2′/coupling/elimination reactions. The method provides a general and convenient approach to the synthesis of various substituted cyclic compounds from the corresponding Baylis–Hillman
Rh(III)-catalyzed synthesis of (dihydro)quinolines via the annulation of N-sulfonyl 2-aminobenzaldehydes with olefins
作者:Yimeng Zhang、Tao Zhang、Haoqiang Zhan、Xingwei Li
DOI:10.1016/s1872-2067(14)60160-1
日期:2014.11
synthetic method for the production of 1,2-dihydroquinolines and quinolines via the Rh(III)-catalyzed annulation of N-sulfonyl 2-aminobenzaldehydes with olefins. Various functionalities were found to be compatible under the operationally simple conditions. This study provides the first example of a Rh(III)-catalyzed synthesis of 1,2-dihydroquinolines.
Visible light catalyzed synthesis of quinolines from (aza)-Morita–Baylis–Hillman adducts
作者:Atul Kumar Chaturvedi、Namrata Rastogi
DOI:10.1039/c8ob02260g
日期:——
A mild and efficient protocol for the synthesis of quinoline scaffolds from (aza)-MBH adducts under visible light catalysis has been established. The reaction involves visible light catalyzed generation of amidyl radicals from (aza)-MBH adducts followed by intramolecular radical cyclization. The reaction exhibits a wide substrate scope, good functional group tolerance and high regioselectivity. This
Synthesis of quinolines from the Baylis–Hillman acetates via the oxidative cyclization of sulfonamidyl radical as the key step
作者:Jae Nyoung Kim、Yun Mi Chung、Yang Jin Im
DOI:10.1016/s0040-4039(02)01314-x
日期:2002.8
Ethyl 3-quinolinecarboxylates 5 were synthesized in good to moderate yields from the Baylis-Hillman acetates 1 via the oxidative cyclization reaction of the N-tosylamidyl radical, which was generated from the rearranged tosylamide derivatives 2 by iodobenzene diacetate and iodine. (C) 2002 Elsevier Science Ltd. All rights reserved.
Synthesis of 3-quinolinecarboxylic acid esters from the Baylis–Hillman adducts of 2-halobenzaldehyde N-tosylimines
作者:Jae Nyoung Kim、Hong Jung Lee、Ka Young Lee、Hyoung Shik Kim
DOI:10.1016/s0040-4039(01)00552-4
日期:2001.5
3-Quinolinecarboxylic acid ethyl esters 4 were prepared from 1. the Baylis-Hillman adducts of o-halobenzaldehyde N-tosylimines, in a one-pot reaction. (C) 2001 Elsevier Science Ltd. All rights reserved.