3-ethoxy-2-hydroxypropyl methacrylate | 23056-16-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 3-ethoxy-2-hydroxypropyl methacrylate
• 英文别名: (3-Ethoxy-2-hydroxypropyl) 2-methylprop-2-enoate
• CAS: 23056-16-8
• 化学式: C₉H₁₆O₄
• 分子量: 188.224
• InChiKey: LDFDLBBOKWEKHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  甲基丙烯酸缩水甘油酯 、 sodium ethanolate 在 吩噻嗪 作用下， 反应 7.0h， 以28%的产率得到2-ethoxy-3-hydroxypropyl methacrylate
  参考文献：
  名称：

  一种（甲基）丙烯酸醚类羟基烷烃酯的合成方法

  摘要：

  本发明涉及有机合成领域，公开了一种（甲基）丙烯酸醚类羟基烷烃酯的合成方法，本发明先采用甲基丙烯酸与环氧氯丙烷反应，生成含有环氧基的丙烯酸酯，然后对环氧基进行定位开环，使羟基位置处于2位碳上，3位上形成位阻的醚键，然后与伯醇类化合物反应生成目标产物，本发明方法合成过程中副反应少，同时可以改变聚合物的结晶性，增强聚合物的拉伸强度等力学性能；还能改变亲水性能。

  公开号：

  CN110054601A

文献信息

• Derivatives of Heptaazaphenalene, Methods for Obtaining Them, and Their Use as Protecting Agents Against Uv Radiation
  申请人：Trullas Carles

  公开号：US20080193398A1

  公开（公告）日：2008-08-14

  The present invention relates to new heptaazaphenalene derivatives of general Formula (I) and to methods for obtaining them. The physicochemical properties of said compounds allow them to be used as UV radiation absorbents.

  本发明涉及一种新的一氮七环苯衍生物，其一般化学式为（I），以及获取它们的方法。所述化合物的物理化学性质使其可以用作紫外辐射吸收剂。
• CURABLE COMPOSITION CONTAINING TRANSITION METAL ADSORBENT
  申请人：Shofu Inc.

  公开号：EP3808324A1

  公开（公告）日：2021-04-21

  To provide a dental curable composition having excellent curability and storage stability. The dental curable composition contains(a) transition metal adsorbent in which a transition metal compound of the period 4 in the periodic table is adsorbed on an inorganic particle which is non-reactive with a transition metal of the period 4 in the periodic table, (b) thiourea derivative, (c) organic peroxide having a hydroperoxide group, and (d) polymerizable monomer, wherein the (d) polymerizable monomer contains (d-1) acidic group-non-containing polymerizable monomer, and wherein a pore volume of the inorganic particle which is non-reactive with a transition metal of the period 4 in the periodic table is 0.2 cc/g or less.

  提供一种具有优异固化性和储存稳定性的牙科固化组合物。该牙科固化组合物包含：(a) 过渡金属吸附剂，其中元素周期表中第 4 周期的过渡金属化合物被吸附在与元素周期表中第 4 周期的过渡金属不反应的无机颗粒上；(b) 硫脲衍生物、(c) 具有过氧化氢基团的有机过氧化物，以及 (d) 可聚合单体，其中 (d) 可聚合单体含有 (d-1) 酸性基团-不含聚合单体，且与元素周期表中周期 4 的过渡金属不反应的无机粒子的孔体积为 0.2 cc/g 或更少。
• DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN COLOR TONE SELECTIVITY
  申请人：Shofu Inc.

  公开号：EP3888616A1

  公开（公告）日：2021-10-06

  To provide a dental photocurable composition having sufficient mechanical property and being excellent in color tone selectivity because of having a small color difference between before curing and after curing. [Solution] To provide a dental photocurable composition, comprising (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator, (D) photopolymerization accelerator and (E) filler, wherein, the dental photocurable composition comprises (B-1) α-diketone compound as the (B) photosensitizer, and the dental photocurable composition comprises, with respect to 100 parts by mass of the (A) polymerizable monomer, 0.15 parts by mass or less of the (B-1) α-diketone compound, 0.5 parts by mass or more of the (C) photoacid generator, and 100 parts by mass or more of the (E) filler.

  提供一种牙科光固化组合物，该组合物具有足够的机械性能，并且由于固化前和固化后的色差很小，因此具有极佳的色调选择性。 [解决方案］ 提供一种牙科光固化组合物，包括 (A) 可聚合单体、(B) 光敏剂、(C) 光酸发生器、(D) 光聚合促进剂和 (E) 填料，其中，牙科光固化组合物包括作为 (B) 光敏剂的 (B-1) α-二酮化合物，并且牙科光固化组合物包括，相对于 100 份（质量）的 (A) 可聚合单体，0.15份（质量份）或更少的(B-1)α-二酮化合物、0.5份（质量份）或更多的(C)光酸发生剂以及100份（质量份）或更多的(E)填料。
• DENTAL COMPOSITION HAVING CHARACTERISTIC IN SILANE COUPLING MATERIAL COMPOUNDING INDEX
  申请人：Shofu Inc.

  公开号：EP3903759A1

  公开（公告）日：2021-11-03

  [Problem] To provide a dental adhesive composition realizing excellent durable adhesive strength with respect to various dental restorative materials for cutting and machining such as glass ceramics containing lithium disilicate, a dental resin for cutting and machining, and a dental resin for cutting and machining made of a glass fiber reinforced resin in particular and with respect to a tooth substance, and having excellent storage stability simultaneously. [Solution] The dental adhesive composition of the present invention comprises a matrix containing (Al) silane coupling material represented by structural formula of [Chemical formula 1], (B) polymerizable monomer having an acidic group and (C) polymerizable monomer having no acidic group, and wherein the (C) polymerizable monomer having no acidic group contains (Cl) polymerizable monomer having no acidic group and having one or more hydroxyl groups, the (Al) silane coupling material represented by structural formula of [Chemical formula 1] and the (Cl) polymerizable monomer having no acidic group and having one or more hydroxyl groups coexist in at least one matrix, and the dental adhesive composition satisfies at least one of following formulas (1) and (2). 0.005≤Total amount of silane coupling material compounding amount index in matrixS1×W1/M1≤0.07 0.001≤Total amount of silane coupling material compounding amount index in compositionS2×W2/M2≤0.015

  问题 提供一种牙科粘合剂组合物，该组合物对含有二硅酸锂的玻璃陶瓷等各种切割和加工用牙科修复材料、切割和加工用牙科树脂、特别是由玻璃纤维增强树脂制成的切割和加工用牙科树脂以及牙科物质具有优异的持久粘合强度，同时具有优异的储存稳定性。 [解决方案］ 本发明的牙科粘合剂组合物包括含有由[化学式 1]结构式表示的（Al）硅烷偶联材料的基质、 (B)具有酸性基团的可聚合单体和(C)不具有酸性基团的可聚合单体，其中(C)不具有酸性基团的可聚合单体包含(Cl)不具有酸性基团且具有一个或多个羟基的可聚合单体、由[化学式 1]结构式表示的（Al）硅烷偶联材料和无酸性基团且具有一个或多个羟基的（Cl）可聚合单体共存于至少一种基质中，且牙科粘合剂组合物满足以下公式（1）和（2）中的至少一个。0.005≤基质中硅烷偶联材料混合物总量指数S1×W1/M1≤0.07 0.001≤组合物中硅烷偶联材料混合物总量指数S2×W2/M2≤0.015
• DENTAL PHOTOCURABLE COMPOSITION HAVING EXCELLENT STORAGE STABILITY
  申请人：Shofu Inc.

  公开号：EP4062894A1

  公开（公告）日：2022-09-28

  To provide a dental photocurable composition having good storage stability of a matrix containing a polymerizable monomer and a polymerization initiator, etc. and excellent mechanical strength of a dental photocurable composition comprising a mixture of the matrix and a filler. The dental photocurable composition of the present invention comprises a matrix containing (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator and (D) photopolymerization accelerator, and (E) filler, wherein, the dental photocurable composition comprises (A1) polymerizable monomer having an acidic group as the (A) polymerizable monomer, and the dental photocurable composition comprises (D1) tertiary aliphatic amine compound having LogP of 2 or more and pKa of 10 or less as the (D) photopolymerization accelerator.

  提供一种牙科光固化组合物，其含有可聚合单体和聚合引发剂等的基质具有良好的储存稳定性，而由基质和填料混合物组成的牙科光固化组合物具有优异的机械强度。本发明的牙科光固化组合物包括含有(A)可聚合单体、(B)光敏剂、(C)光酸发生器和(D)光聚合促进剂以及(E)填料的基质，其中、牙科光固化组合物包含作为 (A) 可聚合单体的 (A1) 具有酸性基团的可聚合单体，以及作为 (D) 光聚合促进剂的 (D1) LogP 为 2 或以上且 pKa 为 10 或以下的叔脂族胺化合物。