2-ethyl-1,5-pentanediol | 14189-13-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-ethyl-1,5-pentanediol
• 英文别名: 2-ethyl-pentane-1,5-diol；2-Aethyl-pentan-1,5-diol；3-Hydroxymethyl-hexanol-(6)；2-Ethylpentane-1,5-diol
• CAS: 14189-13-0
• 化学式: C₇H₁₆O₂
• 分子量: 132.203
• InChiKey: DEPDXIXAMMDTBV-UHFFFAOYSA-N

物化性质

• 熔点：
  44.24°C (estimate)
• 沸点：
  233.16°C (rough estimate)
• 密度：
  0.9744 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-ethyl-1,5-pentanediol 在 氢溴酸 作用下， 生成 1-bromo-4-bromomethyl-hexane
  参考文献：
  名称：

  v. Braun; Mannes; Reuter, Chemische Berichte, 1933, vol. 66, p. 1499,1501

  摘要：

  DOI：
• 作为产物：
  描述：

  2-乙基戊二酸二乙酯 在 乙醇 、 sodium 作用下， 生成 2-ethyl-1,5-pentanediol
  参考文献：
  名称：

  v. Braun; Mannes; Reuter, Chemische Berichte, 1933, vol. 66, p. 1499,1501

  摘要：

  DOI：

文献信息

• Stable crystalline salt of (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester
  申请人：Laboratorios SALVAT, S.A.

  公开号：EP2065385A1

  公开（公告）日：2009-06-03

  The present invention refers to a stable crystalline salt of (R)-3-fluorophenyl- 3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-3-yl ester of formula (I) and its use as medicament, in particular for the treatment of urinary incontinence or other diseases involving genitourinary disorders.

  本发明涉及一种稳定的晶体盐，其为(R)-3-氟苯基-3,4,5-三氟苯甲基碳酸酯1-氮杂双环[2.2.2]辛-3-基酯的化学式(I)，以及其作为药物的用途，特别是用于治疗尿失禁或其他涉及泌尿系统疾病的药物。
• Benzamidine derivatives
  申请人：SANKYO COMPANY, LIMITED

  公开号：US20040248981A1

  公开（公告）日：2004-12-09

  Benzamidine derivatives of formula (I) or pharmaceutically acceptable salts thereof exhibit excellent inhibitory activity against factor Xa and are useful for treating or preventing blood coagulation disorders: 1 wherein R 1 represents a hydrogen atom, a halogen atom, an alkyl group or a hydroxyl group; R 2 represents a hydrogen atom, a halogen atom or an alkyl group, R 3 represents a hydrogen atom, an optionally substituted alkyl group, an aralkyl group, an optionally substituted alkanoyl group or an optionally substituted alkylsulfonyl group, R 4 and R 5 are the same as or different from each other and each represent a hydrogen atom, a halogen atom, an optionally substituted alkyl group, an alkoxy group, a carboxyl-group, an alkoxycarbonyl group or an optionally substituted carbamoyl group, and R 6 represents a substituted pyrrolidine group or substituted piperidine group.

  公式（I）中的苯甲酰胺衍生物或其药学上可接受的盐表现出优异的抑制因子Xa的活性，可用于治疗或预防血液凝固障碍：其中R1代表氢原子，卤原子，烷基或羟基；R2代表氢原子，卤原子或烷基，R3代表氢原子，可选取代的烷基，芳基烷基，可选取代的烷酰基或可选取代的烷基磺酰基，R4和R5相同或不同，每个代表氢原子，卤原子，可选取代的烷基，烷氧基，羧基，烷氧羰基或可选取代的氨基甲酰基，而R6代表取代的吡咯烷基或取代的哌嗪烷基。
• Lubricating oil compositions, concentrates and the use thereof
  申请人：ETHYL PETROLEUM ADDITIVES, INC.

  公开号：EP0493928A1

  公开（公告）日：1992-07-08

  Oleaginous compositions and additive concentrates therefor having enhanced performance characteristics comprise at least a) one or more oil-soluble metal dihydrocarbyl dithiophosphates or dithiocarbamates; and b) one or more oil-soluble additive compositions formed by heating concurrently or in any sequence at least one ashless dispersant which contains basic nitrogen and/or at least one hydroxyl group with (i) at least one inorganic phosphorus acid or anhydride, or at least one partial or total sulfur analog thereof, or any combination of the foregoing; or (ii) at least one water-hydrolyzable organic phosphorus compound and water; and (iii) at least one boron compound; such that a phosphorus- and boron-containing liquid composition is formed, and from which excessive water, if present, has been removed at least during or after heating with (ii), if used.

  具有增强性能特征的油胶组合物及其添加剂浓缩物至少包括 a) 一种或多种油溶性金属二氢羰基二硫代磷酸酯或二硫代氨基甲酸酯；(b) 一种或多种油溶性添加剂组合物，通过同时或任意顺序加热至少一种无 灰分散剂而形成，该分散剂含有碱性氮和/或至少一个羟基与 (i) 至少一种无机磷酸或磷酸酐，或至少一种其部分或全部硫类似物， 或上述物质的任意组合；或 (ii) 至少一种可水解的有机磷化合物和水；以及 (iii) 至少一种硼化合物；这样就形成了一种含磷和硼的液体组合物，如果使用了(ii)，在加热过程中或加热后，过量的水分（如果存在）已被去除。
• PROCESS FOR PREPARING 1,5-PENTANEDIOL DERIVATIVE
  申请人：Kyowa Yuka Co., Ltd.

  公开号：EP0807617A1

  公开（公告）日：1997-11-19

  (In the formulae, R1 and R2, which may be the same or different, each represents hydrogen or lower alkyl.) The present invention relates to a process for producing 1,5-pentanediol derivatives represented by general formula (II) which comprises reacting 2-butenal derivatives represented by general formula (I) with formaldehyde, and hydrogenating the obtained mixture of reaction products.

  (在式中，R1和R2可以相同或不同，各自代表氢或低级烷基）。 本发明涉及一种生产通式（II）所代表的 1,5-戊二醇衍生物的工艺，该工艺包括使通式（I）所代表的 2-丁烯醛衍生物与甲醛反应，并对得到的反应产物混合物进行氢化。
• Resin composition with high vibration damping ability
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP1571176A1

  公开（公告）日：2005-09-07

  A resin composition contains dicarboxylic acid constitutional units and diol constitutional units and at least one of an electroconductive material and filler which is dispersed in the polyester resin. The polyester resin satisfies the relationship, 0.5 ≤ (A1 + B1)/(A0 + B0) ≤ 1, wherein A0 is the number of total dicarboxylic acid constitutional units, B0 is the number of total diol constitutional units, A1 is the number of dicarboxylic acid constitutional units having an odd number of carbon atoms in a polyester main chain, and B1 is the number of diol constitutional units having an odd number of carbon atoms in the polyester main chain. The resin composition exhibits a high vibration damping ability.

  一种树脂组合物含有二羧酸结构单元和二元醇结构单元，以及至少一种导电材料和填料，它们分散在聚酯树脂中。聚酯树脂满足 0.5 ≤ (A1 + B1)/(A0 + B0) ≤ 1 的关系，其中 A0 是二羧酸结构单元总数，B0 是二元醇结构单元总数，A1 是聚酯主链中碳原子数为奇数的二羧酸结构单元数，B1 是聚酯主链中碳原子数为奇数的二元醇结构单元数。该树脂组合物具有很高的减震能力。