2-hydroxy-4-isopropoxybenzoic acid | 163618-97-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-hydroxy-4-isopropoxybenzoic acid
• 英文别名: 4-isopropoxysalicylic acid；2-Hydroxy-4-isopropyloxy-benzoesaeure；2-hydroxy-4-propan-2-yloxybenzoic acid
• CAS: 163618-97-1
• 化学式: C₁₀H₁₂O₄
• 分子量: 196.203
• InChiKey: JUIYTAQAHOONSH-UHFFFAOYSA-N

物化性质

• 沸点：
  340.3±27.0 °C(Predicted)
• 密度：
  1.243±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  甲醇 、 2-hydroxy-4-isopropoxybenzoic acid 在 HCl (20percent in Et₂O) 作用下， 反应 50.0h， 以88%的产率得到2-羟基-4-异丙氧基苯甲酸甲酯
  参考文献：
  名称：

  Stability and Chemical Reactivity of 7-Isopropoxyisoflavone (Ipriflavone)

  摘要：

  DOI：

  10.1002/1099-0690(200110)2001:20<3911::aid-ejoc3911>3.0.co;2-0
• 作为产物：
  描述：

  2',4'-二羟基-2-苯基苯乙酮 在 sodium hydroxide 、 potassium carbonate 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 245.0h， 生成 2-hydroxy-4-isopropoxybenzoic acid
  参考文献：
  名称：

  Stability and Chemical Reactivity of 7-Isopropoxyisoflavone (Ipriflavone)

  摘要：

  DOI：

  10.1002/1099-0690(200110)2001:20<3911::aid-ejoc3911>3.0.co;2-0

文献信息

• EXTRACT POWDER OF INDIGO PLANT, AND ITS PREPARATION AND USES
  申请人：Fujii Mitsukiyo

  公开号：US20100034757A1

  公开（公告）日：2010-02-11

  The present invention has objects to provide an extract powder of indigo plant, which has a relatively low hygroscopicity, satisfactory fluidability, and improved storage stability; a process thereof; and a composition incorporated with the extract powder. The objects are solved by a process for producing an extract powder of indigo plant, which comprises incorporating a partial starch hydrolyzate with a dextrose equivalent of 10.2 or lower into one part by weight, on a dry solid basis, of an indigo plant extract contained in a liquid extract of indigo plant in an amount of not lower than 0.25 part by weight but not higher than 5 parts by weight, on a dry solid basis, and drying the resulting mixture; an extract powder of indigo plant prepared thereby; and a composition incorporated with the extract powder.

  本发明旨在提供一种靛蓝植物的提取粉末，其具有相对较低的吸湿性、满意的流动性和改善的储存稳定性；其制备方法；以及与提取粉末混合的组合物。通过将DE值为10.2或更低的部分淀粉水解物以不低于0.25份重量但不高于5份重量的干固物基础加入到液态提取的靛蓝植物提取物的一份重量中，并将所得混合物干燥，来解决上述问题；由此制备的靛蓝植物提取粉末；以及与提取粉末混合的组合物。
• OIL-IN-WATER EMULSION COMPOSITION
  申请人：SHISEIDO COMPANY, LTD.

  公开号：US20150328124A1

  公开（公告）日：2015-11-19

  The present invention provides an oil-in-water emulsion composition that is high in the moisturizing effect and the skin smoothing effect, excellent in the improving effect on wrinkles and elasticity, good in spreadability during application, and without an oily feeling and sticky feeling. The oil-in-water emulsion composition of the present invention is characterized by comprising the below-described components (a) hyaluronic acid or a salt thereof, (b) ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymer, (c) water-holding oil, (d) glycerin, and (e) ethanol.

  本发明提供一种油水乳化物组合物，具有高保湿效果和皮肤平滑效果，对皱纹和弹性的改善效果优异，在使用过程中具有良好的延展性，没有油腻感和黏腻感。本发明的油水乳化物组合物的特征在于包括以下所述的组分：（a）透明质酸或其盐，（b）丙烯酰基二甲基牛脂酰胺/十五烷基-25 甲基丙烯酸酯交联聚合物，（c）保水油，（d）甘油和（e）乙醇。
• EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME
  申请人：HAYASHIBARA CO., LTD.

  公开号：US20150342854A1

  公开（公告）日：2015-12-03

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用皮肤组成物，该组成物可以预防或改善因年龄增长或衰老引起的皮肤问题，如皱纹、细纹、斑点和下垂，并维持或改善皮肤的屏障功能和透明质酸的产生。本发明通过提供一种外用皮肤组成物来实现该目的，该组成物包含水性介质作为基材料，并含有一种或多种从L-抗坏血酸、其衍生物和它们的盐中选择的成分作为有效成分。
• AGENT FOR EXTERNAL APPLICATION TO THE SKIN
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP1894558A1

  公开（公告）日：2008-03-05

  The present invention has an object to provide an agent for suppressing melanin production and/or inhibiting elastase activity containing a plant extract as an effective substance with high safety and acceptable levels of stability and odor or sediment formation and an agent for external application to the skin comprising the above agent which has excellent effects in skin-whitening and skin-beautifying. The object is attained by providing an agent for external application to the skin containing indigo-plant extract.

  本发明的目的是提供一种抑制黑色素生成和/或抑制弹性蛋白酶活性的制剂，该制剂含有一种植物提取物作为有效物质，安全性高，稳定性和气味或沉淀物的形成水平可接受，并提供一种由上述制剂组成的皮肤外用制剂，该制剂在皮肤美白和皮肤美容方面具有极佳的效果。通过提供一种含有靛蓝植物提取物的皮肤外用制剂，可以达到上述目的。
• EXTRACT POWDER OF INDIGO-CONTAINING PLANT, METHOD FOR PRODUCTION THEREOF, AND USE THEREOF
  申请人：Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo

  公开号：EP2087903A1

  公开（公告）日：2009-08-12

  The present invention has objects to provide an extract powder of indigo plant, which has a relatively low hygroscopicity, satisfactory fluidability, and improved storage stability; a process thereof; and a composition incorporated with the extract powder. The objects are solved by a process for producing an extract powder of indigo plant, which comprises incorporating a partial starch hydrolyzate with a dextrose equivalent of 10.2 or lower into one part by weight, on a dry solid basis, of an indigo plant extract contained in a liquid extract of indigo plant in an amount of not lower than 0.25 part by weight but not higher than 5 parts by weight, on a dry solid basis, and drying the resulting mixture; an extract powder of indigo plant prepared thereby; and a composition incorporated with the extract powder.

  本发明的目的是提供一种吸湿性相对较低、流动性令人满意、贮存稳定性更好的靛蓝植物提取物粉末；其工艺；以及掺入该提取物粉末的组合物。本发明的目的是通过一种生产蓝靛花提取物粉末的工艺来解决的，该工艺包括将葡萄糖当量为 10.2 或更低的部分淀粉水解物加入到蓝靛花液体提取物中所含的蓝靛花提取物中，以干固体为基础，加入量不低于 0.25 重量份，但不高于 5 重量份，并干燥所得混合物；由此制备蓝靛花提取物粉末；以及加入该提取物粉末的组合物。