4-methylphenyl pyridine-3-carboxylate | 3468-51-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: 4-methylphenyl pyridine-3-carboxylate
• 英文别名: nicotinic acid p-tolyl ester；Nicotinsaeure-p-tolylester；(4-methylphenyl) pyridine-3-carboxylate
• CAS: 3468-51-7
• 化学式: C₁₃H₁₁NO₂
• mdl: MFCD00518440
• 分子量: 213.236
• InChiKey: YBUBSLHHVFYHMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.076
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  烟酸 在 Sodium thiosulfate pentahydrate 、 甲基磺酰氯 、 三乙胺 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 21.0h， 生成 4-methylphenyl pyridine-3-carboxylate
  参考文献：
  名称：

  通过硫代硫酸钠催化的硫代酸替代物介导的苯酚的位点选择性酰化

  摘要：

  硫代硫酸钠用作硫源，与酸酐反应生成酰基-邦特盐，然后引发与酚类的反应。该协议可用于在存在其他醇基的情况下对酚羟基进行位点选择性酰化。这种酰化方法的优点是操作简单、效率高、使用无味、毒性低的试剂。

  DOI：

  10.1021/acs.orglett.2c01467

文献信息

• [EN] PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV<br/>[FR] COMPOSES PYRIDINES UTILISES COMME INHIBITEURS DE DIPEPTIDYLE PEPTIDASE IV
  申请人：TAKEDA PHARMACEUTICAL

  公开号：WO2005042488A1

  公开（公告）日：2005-05-12

  A compound represented by the formula wherein R1 and R2 are the same or different and each is an optionally substituted hydrocarbon group or an optionally substituted hydroxy group; R3 is an optionally substituted aromatic group; R4 is an optionally substituted amino group; L is a divalent chain hydrocarbon group; Q is a bond or a divalent chain hydrocarbon group; and X is a hydrogen atom, a cyano group, a nitro group, an acyl group, a substituted hydroxy group, an optionally substituted thiol group, an optionally substituted amino group or an optionally substituted cyclic group; provided that when X is an ethoxycarbonyl group, then Q is a divalent chain hydrocarbon group. The compound has a peptidase inhibitory action, is useful as an agent for the prophylaxis or treatment of diabetes and the like, and is superior in efficacy, duration of action, specificity, lower toxicity and the like.

  该化合物的化学式表示为其中R1和R2相同或不同，每个都是可选择取代的碳氢基团或可选择取代的羟基团；R3是可选择取代的芳香基团；R4是可选择取代的氨基团；L是二价链状碳氢基团；Q是键或二价链状碳氢基团；X是氢原子、氰基、硝基、酰基、取代的羟基团、可选择取代的硫醇基团、可选择取代的氨基团或可选择取代的环状基团；但当X是乙氧羰基团时，Q为二价链状碳氢基团。该化合物具有肽酶抑制作用，可用作糖尿病等疾病的预防或治疗药物，并在功效、作用持续时间、特异性、毒性较低等方面具有优越性。
• Functionalized Photoreactive Compounds
  申请人：Cherkaoui Mohammed Zoubair

  公开号：US20080274304A1

  公开（公告）日：2008-11-06

  The present invention concerns functionalized photoreactive compounds of formula (I), that are particularly useful in materials for the alignment of liquid crystals. Due to the adjunction of an electron withdrawing group to specific molecular systems bearing an unsaturation directly attached to two unsaturated ring systems, exceptionally high photosensitivities, excellent alignment properties as well as good mechanical robustness could be achieved in materials comprising said functionalized photoreactive compounds of the invention.

  本发明涉及式(I)的官能化光反应化合物，特别适用于液晶对准材料。由于在特定分子系统中的不饱和键直接连接到两个不饱和环系统上附加了一个电子受体基团，因此在包含本发明的这些官能化光反应化合物的材料中可以实现异常高的光敏性、优异的对准性能以及良好的机械稳健性。
• Pigment dispersion liquid, curable composition, film, near infrared cut filter, solid-state imaging element, image display device, and infrared sensor
  申请人：FUJIFILM Corporation

  公开号：US11015077B2

  公开（公告）日：2021-05-25

  Provided is a pigment dispersion liquid used in a curable composition capable of manufacturing a film having fewer foreign matters. Provided are a curable composition capable of manufacturing a film having fewer foreign matters, a film, a near infrared cut filter, a solid-state imaging element, an image display device, and an infrared sensor. The pigment dispersion liquid includes a near infrared absorbing organic pigment having an maximum absorption wavelength in a wavelength range of 600 to 1,200 nm; two or more kinds of pigment derivatives having different structures; and a solvent.

  本发明提供了一种用于可固化组合物的颜料分散液，该组合物能够制造异物较少的薄膜。本发明提供了一种能够制造异物较少的薄膜的可固化组合物、薄膜、近红外切割滤光片、固态成像元件、图像显示装置和红外传感器。颜料分散液包括最大吸收波长在 600-1,200 纳米范围内的近红外吸收有机颜料；两种或两种以上具有不同结构的颜料衍生物；以及溶剂。
• Composition, curable composition, cured film, near infrared cut filter, infrared transmitting filter, solid image pickup element, infrared sensor, and camera module
  申请人：FUJIFILM Corporation

  公开号：US11209582B2

  公开（公告）日：2021-12-28

  Provided are a composition that has excellent pigment dispersibility without affecting the color of a pigment in a visible range, a curable composition, a cured film, a near infrared cut filter, an infrared transmitting filter; a solid image pickup element, an infrared sensor, and a camera module. The composition includes: a pigment; a pigment derivative that includes a compound represented by Formula (1); and a solvent, in which R1 and R2 represent an aryl group or the like, R3 to R6 represent a cyano group, a heteroaryl group, or the like, R7 and R8 each independently represent —BR9R10 or the like, R9 and R10 each independently represent a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a heteroaryl group, an alkoxy group, an aryloxy group, or a heteroaryloxy group, L represents a single bond or a linking group, X represents an acidic group or the like, m represents an integer of 1 to 10, and n represents an integer of 1 to 10.

  本发明提供了一种在不影响可见光范围内颜料颜色的情况下具有优异颜料分散性的组合物、一种可固化组合物、一种固化薄膜、一种近红外切割滤光片、一种红外透射滤光片；一种固体图像拾取元件、一种红外传感器和一种相机模块。组合物包括颜料；颜料衍生物，包括由式（1）表示的化合物；和溶剂，其中 R1 和 R2 代表芳基或类似物，R3 至 R6 代表氰基、杂芳基或类似物，R7 和 R8 各自独立地代表 -BR9R10 或类似物，R9 和 R10 各自独立地代表氢原子、卤素原子、烷基、芳基或类似物、烷基、芳基、杂芳基、烷氧基、芳氧基或杂芳基氧基，L 代表单键或连接基团，X 代表酸性基团或类似基团，m 代表 1 至 10 的整数，n 代表 1 至 10 的整数。
• N-heterocyclic carbenes: IX. Oxidative esterification of aromatic aldehydes with arylboronic acids catalyzed by N-heterocyclic carbenes
  作者：M. S. Denisov、A. A. Gorbunov、V. A. Glushkov

  DOI：10.1134/s1070428015010145

  日期：2015.1

  Aromatic aldehydes reacted with arylboronic acids under catalysis by N-heterocyclic carbene and oxic conditions to produce phenol esters.