(4-chloro-6-methyl-[1,3,5]triazin-2-yl)-p-tolyl-amine | 54871-31-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-chloro-6-methyl-[1,3,5]triazin-2-yl)-p-tolyl-amine
• 英文别名: 4-Chlor-6-methyl-2-p-toluidino-1,3,5-triazin；4-chloro-6-methyl-N-(4-methylphenyl)-1,3,5-triazin-2-amine
• CAS: 54871-31-7
• 化学式: C₁₁H₁₁ClN₄
• 分子量: 234.688
• InChiKey: CDUFFTGXTPUMAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  50.7
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N-乙基苄胺 、 (4-chloro-6-methyl-[1,3,5]triazin-2-yl)-p-tolyl-amine 生成 2-N-benzyl-2-N-ethyl-6-methyl-4-N-(4-methylphenyl)-1,3,5-triazine-2,4-diamine
  参考文献：
  名称：

  快速微量合成，这是一种使用机器人技术和溶液相化学进行铅优化的新方法：在促肾上腺皮质激素释放因子1受体拮抗剂的合成和优化中的应用。

  摘要：

  DOI：

  10.1021/jm960148m
• 作为产物：
  描述：

  2,4-二氯-6-甲基-1,3,5-三嗪 、 乙烷,三氯氟- 以 四氢呋喃 为溶剂， 反应 0.17h， 生成 (4-chloro-6-methyl-[1,3,5]triazin-2-yl)-p-tolyl-amine
  参考文献：
  名称：

  快速微量合成，这是一种使用机器人技术和溶液相化学进行铅优化的新方法：在促肾上腺皮质激素释放因子1受体拮抗剂的合成和优化中的应用。

  摘要：

  DOI：

  10.1021/jm960148m

文献信息

• JOSHUA C. P.; RAJAN V. P., AUSTRAL. J. CHEM. <AJCH-AS>, 1974, 27, NO 12, 2627-2634
  作者：JOSHUA C. P.、 RAJAN V. P.

  DOI：——

  日期：——
• Reactive Triphendioxazine Dyes, Methods for the Production Thereof, and Use Thereof
  申请人：Ehrenberg Stefan

  公开号：US20080114166A1

  公开（公告）日：2008-05-15

  The present invention relates to triphendioxazine dye of the general formula I where A 1 and A 2 , B, R 1 and M are each as defined in the claims and Y 1 is a group of the general formula II or III where X 1 to X 4 and also R 2 and R 3 are each as defined in the claims, processes for their preparation and their use for dyeing and printing hydroxyl- and/or carboxamido-containing materials.
• SELF-DISPERSED PIGMENTS AND METHODS FOR MAKING AND USING THE SAME
  申请人：Sujeeth Puthalath K.

  公开号：US20120118205A1

  公开（公告）日：2012-05-17

  A method of modifying a pigment that includes reacting a reactive compound having an X—[Y] n reactive group with a secondary compound N—S—ZM to form a substituted reactive intermediate [Y] a —X—(N—S—ZM) b . A pigment is reacted with the substituted reactive intermediate [Y] a —X—(N—S—ZM) b to attach the substituted reactive intermediate to the surface of the pigment to form a surface modified pigment. X may be a sulfonyl, phosphoryl, or 1,3,5-triazinyl group, Y may be a halogen leaving group, N may be a basic nucleophilic group, S may be an organic group, and ZM may be an ionizable end group. Also, n is an integer between 1 and 3, b is an integer between 1 and 3, and a=n−b. When n is equal to or greater than b, and if b is 2 or 3, each N—S—ZM can be the same or different.
• US7414129B2
  申请人：——

  公开号：US7414129B2

  公开（公告）日：2008-08-19
• Rapid Microscale Synthesis, a New Method for Lead Optimization Using Robotics and Solution Phase Chemistry:  Application to the Synthesis and Optimization of Corticotropin-Releasing Factor₁ Receptor Antagonists
  作者：Jeffrey P. Whitten、Yun Feng Xie、Philip E. Erickson、Thomas R. Webb、Errol B. De Souza、Dimitri E. Grigoriadis、James R. McCarthy

  DOI：10.1021/jm960148m

  日期：1996.1.1