[2-(5-ethoxy-indol-3-yl)-ethyl]-methyl-amine | 70310-82-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: [2-(5-ethoxy-indol-3-yl)-ethyl]-methyl-amine
• 英文别名: [2-(5-Aethoxy-indol-3-yl)-aethyl]-methyl-amin；2-(5-ethoxy-1H-indol-3-yl)-N-methylethanamine
• CAS: 70310-82-6
• 化学式: C₁₃H₁₈N₂O
• 分子量: 218.299
• InChiKey: OJYLRVHEILMFSU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  37
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  ethyl magnesium iodide 、 [2-(5-ethoxy-indol-3-yl)-ethyl]-methyl-amine 在 乙醚 作用下， 生成 (+-)-5-ethoxy-1,3a-dimethyl-(3ar,8ac)-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole
  参考文献：
  名称：

  Hoshino; Kobayashi, Justus Liebigs Annalen der Chemie, 1935, vol. 520, p. 11,17

  摘要：

  DOI：
• 作为产物：
  描述：

  N-[2-(5-ethoxy-indol-3-yl)-ethyl]-N-methyl-toluene-4-sulfonamide 在 乙醇 、 aniline hydrochloride 、 苯胺 作用下， 生成 [2-(5-ethoxy-indol-3-yl)-ethyl]-methyl-amine
  参考文献：
  名称：

  Hoshino; Kobayashi, Justus Liebigs Annalen der Chemie, 1935, vol. 520, p. 11,17

  摘要：

  DOI：

文献信息

• Hoshino; Shimodaira, Justus Liebigs Annalen der Chemie, 1935, vol. 520, p. 19,26
  作者：Hoshino、Shimodaira

  DOI：——

  日期：——
• TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH
  申请人：STAMETS Paul Edward

  公开号：US20210069170A1

  公开（公告）日：2021-03-11

  Described herein are neurotrophic and nootropic compositions and methods for treating subjects with such compositions. In one aspect the composition comprises one or more tryptamines or in pure form or extracts from psilocybin containing mushrooms, or combinations thereof optionally combined with one or more phenethylamines or amphetamines in pure form or extracts from a plant or mushroom, or combinations thereof, optionally one or more erinacines or hericenones in pure form, extracts from Hericium mushroom species (e.g., H. erinaceus, H. coralloides, H. ramosum ) or combinations thereof, optionally one or more cannabinoids in pure form or extracts from Cannabis sativa, Cannabis sativa, Cannabis indica , or Cannabis ruderalis , optionally, one or more adversive compounds, and optionally one or more pharmaceutically acceptable excipients.
• [EN] TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH<br/>[FR] COMPOSITIONS DE TRYPTAMINES DESTINÉES À AMÉLIORER L'EXCROISSANCE DES NEURITES
  申请人：STAMETS PAUL EDWARD

  公开号：WO2021101926A1

  公开（公告）日：2021-05-27

  Described herein are neurotrophic and nootropic compositions and methods for treating subjects with such compositions. In one aspect the composition comprises one or more tryptamines or in pure form or extracts from psilocybin containing mushrooms, or combinations thereof optionally combined with one or more phenethylamines or amphetamines in pure form or extracts from a plant or mushroom, or combinations thereof, optionally one or more erinacines or hericenones in pure form, extracts from Hericium mushroom species (e.g., H. erinaceus, H. coralloides, H. ramosum) or combinations thereof, optionally one or more cannabinoids in pure form or extracts from Cannabis sativa, Cannabis sativa, Cannabis indica, or Cannabis ruderalis, optionally, one or more adversive compounds, and optionally one or more pharmaceutically acceptable excipients.
• Hoshino; Kobayashi, Justus Liebigs Annalen der Chemie, 1935, vol. 520, p. 11,17
  作者：Hoshino、Kobayashi

  DOI：——

  日期：——