2,5-Diethoxy-anisol | 19551-78-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2,5-Diethoxy-anisol
• 英文别名: Benzene, 1,4-diethoxy-2-methoxy；1,4-diethoxy-2-methoxybenzene
• CAS: 19551-78-1
• 化学式: C₁₁H₁₆O₃
• 分子量: 196.246
• InChiKey: RZYSCVILLRMWEV-UHFFFAOYSA-N

物化性质

• 熔点：
  44-45 °C
• 沸点：
  148-152 °C(Press: 17 Torr)
• 密度：
  1.009±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,5-Diethoxy-anisol 在 platinum(IV) oxide 氢气 、 三溴化磷 、 碳酸氢钠 、 三氯氧磷 作用下， 以 苯 为溶剂， 生成 2,5-Diethoxy-4-methoxybenzylbromid
  参考文献：
  名称：

  Birch,A.J. et al., Journal of the Chemical Society. Perkin transactions I, 1975, p. 2492 - 2501

  摘要：

  DOI：
• 作为产物：
  描述：

  4-羟基-2-甲氧基苯甲醛 在 sodium hydroxide 、 双氧水 、 potassium carbonate 作用下， 生成 2,5-Diethoxy-anisol
  参考文献：
  名称：

  Birch,A.J. et al., Journal of the Chemical Society. Perkin transactions I, 1975, p. 2492 - 2501

  摘要：

  DOI：

文献信息

• Synthesis of structurally simplified analogues of aplidinone A, a pro-apoptotic marine thiazinoquinone
  作者：Anna Aiello、Ernesto Fattorusso、Paolo Luciano、Marialuisa Menna、Marco A. Calzado、Eduardo Muñoz、Francesco Bonadies、Marcella Guiso、Maria Filomena Sanasi、Gianfranco Cocco、Rosario Nicoletti

  DOI：10.1016/j.bmc.2009.11.063

  日期：2010.1

  The synthesis of analogues of aplidinone A (7), a prenylated quinone isolated from the Mediterranean ascidian Aplidium conicum, has been performed. This work not only allowed confirming the structural assignment of aplidinone A, previously made with the support of GIAO shielding calculations, but, above all, made a series of structurally related quinone derivatives (compounds 8-13 and the natural metabolite) available for a screening in vitro for cytotoxic and pro-apoptotic activity and for SAR studies. The study evidenced one of the synthetic analogues (11) as a potent cytotoxic and pro-apoptotic agent against several tumor cell lines which also inhibits the TNF alpha-induced NF-kappa B activation in a human leukemia T cell line. This exemplifies the potential of a natural product to qualify as lead structure for medicinal chemistry campaigns, affording simplified analogues with better bioactivity and easier to synthesize. (C) 2009 Elsevier Ltd. All rights reserved.
• King et al., Journal of the Chemical Society, 1954, p. 4594,4599
  作者：King et al.

  DOI：——

  日期：——
• Ethyl homologs of 2,4,5-trimethoxyphenylisopropylamine
  作者：Alexander T. Shulgin

  DOI：10.1021/jm00307a056

  日期：1968.1
• Kitahara, Yoshiyasu; Nakahara, Shinsuke; Tanaka, Yoshihiro, Heterocycles, 1992, vol. 34, # 8, p. 1623 - 1630
  作者：Kitahara, Yoshiyasu、Nakahara, Shinsuke、Tanaka, Yoshihiro、Kubo, Akinori

  DOI：——

  日期：——
• ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20170336728A1

  公开（公告）日：2017-11-23

  An object of the present invention is to provide an ultraviolet curing liquid composition having high sensitivity, excellent storage stability, low viscosity, and excellent fixability after ultraviolet curing. The ultraviolet curable liquid composition of the present invention is an ultraviolet curable liquid composition containing a cationically polymerizable liquid monomer, a photopolymerization initiator and a photopolymerization sensitizer, wherein the cationically polymerizable liquid monomer is a vinyl ether compound, the photopolymerization initiator includes a compound represented by general formula (1), and the photopolymerization sensitizer includes (A) at least one compound selected from the group consisting of a compound represented by general formula (2) and a compound represented by general formula (3), and (B) at least one compound selected from the group consisting of a compound represented by general formula (4) and a compound represented by general formula (5).