[(2'-nitrobiphenyl-2-yl)methylidene]propanedioic acid | 1290560-34-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(2'-nitrobiphenyl-2-yl)methylidene]propanedioic acid
• 英文别名: 2-[[2-(2-Nitrophenyl)phenyl]methylidene]propanedioic acid；2-[[2-(2-nitrophenyl)phenyl]methylidene]propanedioic acid
• CAS: 1290560-34-7
• 化学式: C₁₆H₁₁NO₆
• 分子量: 313.266
• InChiKey: WSUJYQIXTQVNLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  120
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  [(2'-nitrobiphenyl-2-yl)methylidene]propanedioic acid 在 三氟化硼乙醚 作用下， 以 乙醚 为溶剂， 反应 15.0h， 生成 C₁₆H₁₁NO₆
  参考文献：
  名称：

  First and mild synthesis of fluorene-9-malonic acid and some substituted derivatives via the intramolecular hydroarylation of 2-phenylbenzylidenemalonic acids

  摘要：

  Hitherto unknown fluorene-9-malonic acid and some substituted derivatives were easily synthesized in very mild conditions through the intramolecular hydroarylation of 2-phenylbenzylidenemalonic acids issued from the corresponding biphenylcarboxaldehydes. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.02.026
• 作为产物：
  描述：

  2-硝基苯基硼酸 在 四(三苯基膦)钯 、 potassium phosphate monohydrate 、 ammonium acetate 作用下， 以 乙二醇二甲醚 、 乙醇 为溶剂， 20.0~150.0 ℃ 、500.01 kPa 条件下， 反应 2.0h， 生成 [(2'-nitrobiphenyl-2-yl)methylidene]propanedioic acid
  参考文献：
  名称：

  First and mild synthesis of fluorene-9-malonic acid and some substituted derivatives via the intramolecular hydroarylation of 2-phenylbenzylidenemalonic acids

  摘要：

  Hitherto unknown fluorene-9-malonic acid and some substituted derivatives were easily synthesized in very mild conditions through the intramolecular hydroarylation of 2-phenylbenzylidenemalonic acids issued from the corresponding biphenylcarboxaldehydes. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.02.026

文献信息

• First and mild synthesis of fluorene-9-malonic acid and some substituted derivatives via the intramolecular hydroarylation of 2-phenylbenzylidenemalonic acids
  作者：Elizabeth Chosson、Christophe Rochais、Remi Legay、Jana Sopkova de Oliveira Santos、Sylvain Rault、Patrick Dallemagne

  DOI：10.1016/j.tet.2011.02.026

  日期：2011.4

  Hitherto unknown fluorene-9-malonic acid and some substituted derivatives were easily synthesized in very mild conditions through the intramolecular hydroarylation of 2-phenylbenzylidenemalonic acids issued from the corresponding biphenylcarboxaldehydes. (C) 2011 Elsevier Ltd. All rights reserved.