3,N-dimethyl-succinamic acid methyl ester | 1161438-27-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3,N-dimethyl-succinamic acid methyl ester
• 英文别名: Methyl 3-methyl-4-(methylamino)-4-oxobutanoate
• CAS: 1161438-27-2
• 化学式: C₇H₁₃NO₃
• 分子量: 159.185
• InChiKey: OMWCYEWYXZGUHC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  55.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-甲基甲酰胺 、 巴豆酸甲酯 在 tetrabutylammonium decatungstate 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以46%的产率得到3,N-dimethyl-succinamic acid methyl ester
  参考文献：
  名称：

  四丁基癸酸铵（Chemo）选择性光催化酰胺中的自由基CH官能化

  摘要：

  贫电子烯烃的光酰胺化是通过酰胺中自由基诱导的CH官能化实现的。使用四丁基癸酸铵作为反应的光催化剂，根据酰胺的结构，可以平稳地生成不同的以碳为中心的自由基。

  DOI：

  10.1002/adsc.200800378

文献信息

• AMATOXIN DERIVATIVES AND CONJUGATES THEREOF AS INHIBITORS OF RNA POLYMERASE
  申请人：Grunewald Jan

  公开号：US20170355731A1

  公开（公告）日：2017-12-14

  The invention disclosed herein relates to cytotoxic cyclic peptides of Formula (I), methods of inhibiting RNA polymerase with such cyclic peptides, immunoconjugates comprising such cyclic peptides (i.e Antibody Drug Conjugates), pharmaceutical compositions comprising such cyclic peptides immunoconjugates, compositions comprising such cyclic peptides immunoconjugates with a therapeutic co-agent and methods of treatment using such cyclic peptides immunoconjugates:
• Control of Industrial Water Treatment Via Digital Imaging
  申请人：Ecolab USA Inc.

  公开号：US20180024031A1

  公开（公告）日：2018-01-25

  A method of analyzing a substrate contacting a fluid present in an industrial system is provided. The method comprises creating a series of digital images of the substrate while contacting the fluid present in the industrial system. A region of interest in the series of digital images of the substrate is defined. A corrosion feature in the region of interest in the series of digital images of the substrate is identified. The corrosion feature in the region of interest in the series of digital images of the substrate is analyzed to determine a corrosion trend of the industrial system. In certain embodiments of the method, the fluid is industrial water, and the industrial system is an industrial water system.
• US7879846B2
  申请人：——

  公开号：US7879846B2

  公开（公告）日：2011-02-01
• Tetrabutylammonium Decatungstate (Chemo)selective Photocatalyzed, Radical CH Functionalization in Amides
  作者：Simone Angioni、Davide Ravelli、Daniele Emma、Daniele Dondi、Maurizio Fagnoni、Angelo Albini

  DOI：10.1002/adsc.200800378

  日期：2008.10.6

  Photoamidation of electron-poor olefins has been achieved by means of a radical-induced CH functionalization in amides. Tetrabutylammonium decatungstate was used as photocatalyst of the reaction and allowed the smooth generation of different carbon-centered radicals depending on the amide structure.

  贫电子烯烃的光酰胺化是通过酰胺中自由基诱导的CH官能化实现的。使用四丁基癸酸铵作为反应的光催化剂，根据酰胺的结构，可以平稳地生成不同的以碳为中心的自由基。