ethane-1,2-diylbis(4-oxopentanoate) | 52406-23-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: ethane-1,2-diylbis(4-oxopentanoate)
• 英文别名: 1,2-bis-levulinoyloxy-ethane；1,2-Bis-laevulinoyloxy-aethan；Ethane-1,2-diyl bis(4-oxopentanoate)；2-(4-oxopentanoyloxy)ethyl 4-oxopentanoate
• CAS: 52406-23-2
• 化学式: C₁₂H₁₈O₆
• 分子量: 258.271
• InChiKey: LIQBLYKFSGXMNN-UHFFFAOYSA-N

物化性质

• 沸点：
  375.0±22.0 °C(Predicted)
• 密度：
  1.133±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  18
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  86.7
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  乙二醇 、 乙酰丙酸 在 4-二甲氨基吡啶 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以71%的产率得到ethane-1,2-diylbis(4-oxopentanoate)
  参考文献：
  名称：

  酰基酸类衍生物及其制备方法和医药用途

  摘要：

  本发明涉及酰基酸类衍生物及其制备方法和医药用途。具体地，本发明涉及通式(I)所示的化合物或其药学上可接受的盐或含有其的药物组合物，以及其作为有效成分在预防和/或治疗肌肉萎缩相关疾病包括肌源性肌肉萎缩、废用性肌肉萎缩、老年性肌肉萎缩、神经源性肌肉萎缩中的用途，以及在预防和/或治疗肥胖症、脂肪肝、心脑血管疾病、代谢性疾病，以及抗衰老中的用途。其中，通式(I)中各基团的定义与说明书中的定义相同。

  公开号：

  CN111253246B

文献信息

• Hachihama; Hayashi, Kogyo Kagaku zasshi / Journal of the Society of Chemical Industry, 1951, vol. 54, p. 695,696
  作者：Hachihama、Hayashi

  DOI：——

  日期：——
• DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME
  申请人：Thirumalai Dhakshanamurthy

  公开号：US20090169481A1

  公开（公告）日：2009-07-02

  A dendritic polymer and a magnetic resonance imaging contrast agent employing the same. The magnetic resonance contrast agent includes the dendritic polymer according to the structure of SP-DZ-L) i ) j or SP-DX-Z-L) i ) j , wherein, S is cyclosilane moiety with j silicon oxygen residual groups, and j is not less than 2; P is and 1 is not less than 1; D is a C 3-30 dendritic moiety having n oxygen residue, and n is not less than 3; X is C 3-30 moiety having bi-functional groups; Z is a C 3-20 moiety having a plurality of functional group; and L is a metal cation.
• WATERBORNE COMPOSITIONS
  申请人：DAINES Alison Margaret

  公开号：US20160237302A1

  公开（公告）日：2016-08-18

  The present invention provides for compositions comprising at least one polyketone; and at least one acyl hydrazide; wherein, the polyketone comprises at least two levulinic acid moieties. The present inventions also provide for novel polyhydrazone compounds. Examples of completely water-soluble compositions comprising acyl hydrazide and polyketone that form polyhydrazones compounds are provided herein. The compositions and polyhydrazones of the present invention are useful in the preparation of coating materials and the formation of films.
• US8303937B2
  申请人：——

  公开号：US8303937B2

  公开（公告）日：2012-11-06
• [EN] WATERBORNE COMPOSITIONS<br/>[FR] COMPOSITIONS EN PHASE AQUEUSE
  申请人：VICTORIA LINK LTD

  公开号：WO2015038012A1

  公开（公告）日：2015-03-19

  The present invention provides for compositions comprising at least one polyketone; and at least one acyl hydrazide; wherein, the polyketone comprises at least two levulinic acid moieties. The present inventions also provide for novel polyhydrazone compounds. Examples of completely water-soluble compositions comprising acyl hydrazide and polyketone that form polyhydrazones compounds are provided herein. The compositions and polyhydrazones of the present invention are useful in the preparation of coating materials and the formation of films.