bis(2,4,5-trichlorophenyl) carbonate | 16947-68-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(2,4,5-trichlorophenyl) carbonate
• 英文别名: carbonic acid bis-(2,4,5-trichloro-phenyl ester)；Kohlensaeure-bis-(2,4,5-trichlor-phenylester)；Bis-(2.4.5-trichlor-phenyl)-carbonat；Bis-<2.4.5-trichlor-phenyl>-carbonat；Di-<2.4.5-trichlor-phneyl>-carbonat；2,4,5-Trichlorophenylcarbonate
• CAS: 16947-68-5
• 化学式: C₁₃H₄Cl₆O₃
• 分子量: 420.891
• InChiKey: WDMHOQRSGBPASQ-UHFFFAOYSA-N

物化性质

• 沸点：
  478.3±45.0 °C(Predicted)
• 密度：
  1.679±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis(2,4,5-trichlorophenyl) carbonate 、 2-(5-fluorouracil-1-yl)-2-(methylthio)ethylamine 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 以100%的产率得到(2,4,5-trichlorophenyl) N-[2-(5-fluoro-2,4-dioxopyrimidin-1-yl)-2-methylsulfanylethyl]carbamate
  参考文献：
  名称：

  McCormick, Joan E.; McElhinney, R. Stanley; McMurry, T. Brian H., Journal of Chemical Research, Miniprint, 1991, p. 1216 - 1239

  摘要：

  DOI：
• 作为产物：
  描述：

  三光气 、 2,4,5-三氯苯酚 在 N,N-二甲基苯胺 作用下， 以 甲苯 为溶剂， 反应 2.0h， 以80%的产率得到bis(2,4,5-trichlorophenyl) carbonate
  参考文献：
  名称：

  McCormick, Joan E.; McElhinney, R. Stanley; McMurry, T. Brian H., Journal of Chemical Research, Miniprint, 1991, p. 1216 - 1239

  摘要：

  DOI：

文献信息

• Polypeptides. Part V. The use of t-butyl 2,4,5-trichlorophenyl carbonate in the synthesis of N-t-butoxycarbonyl amino-acids and their 2,4,5-trichlorophenyl esters
  作者：Wallace Broadbent、J. S. Morley、B. E. Stone

  DOI：10.1039/j39670002632

  日期：——

  t-Butyl 2,4,5-trichlorophenyl carbonate, conveniently prepared from phosgene in two stages, reacts cleanly with amino-acids in the presence of bases to give N-t-butoxycarbonyl amino-acids (and 2,4,5-trichlorophenol) in excellent yield. By co-extraction of the N-t-butoxycarbonyl amino-acid and 2,4,5-trichlorophenol from the acidified reaction mixture, followed by treatment of the extracts with NN′-

  碳酸叔丁酯2,4,5-三氯苯甲酸，方便地从光气中分两步制备，在碱的存在下与氨基酸干净地反应，得到N-叔丁氧羰基氨基酸（和2,4,5-三氯苯酚）的良率。由的共萃取Ñ -t丁氧羰基氨基酸及从所述酸化反应混合物2,4,5-三氯苯酚，接着处理所述提取物的具有NN '-dicyclohexylcarbodi酰亚胺，相应的高收率Ñ -t得到-丁氧基羰基氨基酸2,4,5-三氯苯基酯。这些活性酯大部分是稳定的结晶固体，可以方便地用于肽合成中。
• [EN] METHOD FOR PURIFYING 1,1-BIS(4'-HYDROXY-3'-METHYLPHENYL)CYCLOHEXANE AND METHODS OF PRODUCING POLYCARBONATES THEREFROM<br/>[FR] PROCEDE DE PURIFICATION DE 1,1-BIS(4'-HYDROXY-3'-METHYLPHENYL)CYCLOHEXANE ET PROCEDES DE PRODUCTION DE POLYCARBONATES A PARTIR DE CE DERNIER
  申请人：GEN ELECTRIC

  公开号：WO2004041761A1

  公开（公告）日：2004-05-21

  A method for purifying 1,1-bis(4'-hydroxy-3'-methylphenyl)cyclohexane comprises dissolving said 1,1-bis(4'-hydroxy-3'-methylphenyl)cyclohexane in a first solvent consisting essentially of an alcohol to form a first solution; filtering said first solution; adding a second solvent consisting essentially of water to the filtered first solution to form a second solution, wherein said second solution comprises about 40 parts to about 95 parts of the first solvent per 100 parts of the combined weight of the first and second solvents; crystallizing said 1,1-bis(4'-hydroxy-3'-methylphenyl)cyclohexane from said second solution to form a first crystalline product; dissolving said first crystalline product in a third solvent to form a third solution, wherein the third solvent comprises an aromatic compound; and crystallizing said 1,1-bis(4'-hydroxy-3'-methylphenyl)cyclohexane from said third solution to produce a second crystalline product.

  一种纯化1,1-双(4'-羟基-3'-甲基苯基)环己烷的方法包括将该1,1-双(4'-羟基-3'-甲基苯基)环己烷溶解在第一溶剂中，该第一溶剂基本上由醇组成，以形成第一溶液；过滤所述第一溶液；向过滤后的第一溶液中加入基本上由水组成的第二溶剂，以形成第二溶液，其中所述第二溶液包含每100份第一和第二溶剂的总重量约40份至约95份的第一溶剂；从所述第二溶液中结晶出所述1,1-双(4'-羟基-3'-甲基苯基)环己烷，以形成第一结晶产物；将所述第一结晶产物溶解在第三溶剂中，其中第三溶剂包括芳香化合物，以形成第三溶液；并从所述第三溶液中结晶出所述1,1-双(4'-羟基-3'-甲基苯基)环己烷，以产生第二结晶产物。
• Method for producing polycarbonate
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0534189A1

  公开（公告）日：1993-03-31

  An aromatic polycarbonate of improved color value and high molecular weight is obtained by the addition of phosphorous acid and/or a phosphorous ester to the melt polycondensation reaction medium containing aromatic diol, carbonate diester and a metal-containing compound as ester interchange catalyst during the polycondensation reaction.

  在缩聚反应过程中，通过向含有芳香族二元醇、碳酸酯二酯和含金属化合物作为酯交换催化剂的熔融缩聚反应介质中添加磷酸和/或磷酯，可获得色值和分子量更高的芳香族聚碳酸酯。
• PROCESS FOR PRODUCING ARYL CARBAMATES
  申请人：UBE INDUSTRIES LIMITED

  公开号：EP0902014A1

  公开（公告）日：1999-03-17

  A process for producing an aryl carbamate of a high purity at a high yield by reacting a diaryl carbonate with an amine compound having one or more hydrogen atoms bonded to the N position in the presence of carboxylic acid(s) of the following general formulae (I): R1-COOH and/or (II): R2-COOH (wherein R1 represents an alkyl or cycloalkyl group having a carbon atom at the α-position, which is bonded to only one hydrogen atom, and R2 represents an alkyl group having a carbon atom at the α-position, which is not bonded to a hydrogen atom).

  一种高纯度、高收率的氨基甲酸芳基酯的生产工艺，该工艺是在下列通式(I)的羧酸存在下，使碳酸二芳基酯与一个或多个氢原子键合在 N 位上的胺化合物反应：R1-COOH 和/或 (II)：R2-COOH（其中 R1 代表烷基或环烷基，在 α 位有一个碳原子，只与一个氢原子键合；R2 代表烷基，在 α 位有一个碳原子，不与氢原子键合）。
• Functionalized silicone resins, methods for their preparation, and use as catalysts
  申请人：Kishan Gurram

  公开号：US20050033002A1

  公开（公告）日：2005-02-10

  Disclosed herein are silicone resins comprising structural units of the formulae: and at least one structural unit selected from the group consisting of: where “A” is a spacer group comprising C 2 to C 50 alkyl groups; “B” and “C” are spacer groups comprising C 2 to C 20 alkyl groups; “M 1 ” comprises a Group III element; R 1 , R 3 , R 6 , and R 7 independently comprise OH, alkyl groups, or alkoxy groups; R 2 and R 4 independently comprise hydrogen, alkali metal, or alkyl groups; and R 5 comprises a alkyl group. Methods for preparing these silicone resins are also disclosed. The silicone resins are useful as catalysts for producing bisphenols.

  本文公开的硅树脂包含式中的结构单元： 和至少一个结构单元组成的组： 其中 "A "是由 C 2 至 C 50 烷基组成的间隔基团；"B "和 "C "是由 C 2 至 C 20 烷基；"M 1 "包括第 III 组元素； R 1 , R 3 , R 6 和 R 7 独立地包括 OH、烷基或烷氧基； R 2 和 R 4 独立地包括氢、碱金属或烷基；以及 R 5 包括一个烷基。还公开了制备这些硅树脂的方法。这些硅树脂可用作生产双酚的催化剂。