bis(3-phenylpropyl) ether | 72666-87-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(3-phenylpropyl) ether
• 英文别名: 1,1'-(oxydi-3,1-propanediyl)dibenzene；bis(3-phenylpropyl)ether；di(3-phenylpropyl) ether；3-phenylpropyl ether；benzylethyl ether；bis-(3-phenyl-propyl)-ether；Bis-(3-phenylpropyl)-ether；3-(3-phenylpropoxy)propylbenzene
• CAS: 72666-87-6
• 化学式: C₁₈H₂₂O
• 分子量: 254.372
• InChiKey: CUVMKDPTHKMHBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  bis(3-phenylpropyl) ether 在 氢溴酸 作用下， 生成 1-溴-3-苯基丙烷
  参考文献：
  名称：

  Morton; Massengale; Gibb, Journal of the American Chemical Society, 1941, vol. 63, p. 326

  摘要：

  DOI：
• 作为产物：
  描述：

  3-苯基丙酸 在 三乙基硅烷 、 indium(III) bromide 、 硫酸 作用下， 以 氯仿 为溶剂， 反应 4.0h， 以86%的产率得到bis(3-phenylpropyl) ether
  参考文献：
  名称：

  羧酸的铟催化还原酯化：酯和对称醚的顺序制备

  摘要：

  描述了通过涉及InBr 3和硫酸的组合催化剂对两种羧酸进行空前的还原二聚以产生酯衍生物的方法。还证明了在同一罐中通过氢化硅烷将酯进行铟催化的脱氧，从而将原位形成的酯顺序转化为对称的醚。

  DOI：

  10.1002/adsc.201100524

文献信息

• Bismuth Trichloride Catalyzed Efficient Reductive Etherification of Carbonyl Compounds with Alcohols: A Novel Method for Preparation of Symmetrical and Unsymmetrical Ethers
  作者：Makoto Wada、Sonoe Nagayama、Kaori Mizutani、Ryoichi Hiroi、Norikazu Miyoshi

  DOI：10.1246/cl.2002.248

  日期：2002.2

  The reductive homocoupling of a carbonyl compound and heterocoupling of a carbonyl compound with a non-protected alcohol were both effected smoothly at room temperature with triethylsilane in the presence of a catalytic amount of bismuth trichloride to afford the corresponding ethers in good yields.

  在室温下，在催化量的三氯化铋存在下，羰基化合物的还原均偶联和羰基化合物与未保护醇的杂偶联均在室温下顺利进行，以良好的收率得到相应的醚。
• Cosmetic compositions
  申请人：Symrise AG

  公开号：EP2745878A1

  公开（公告）日：2014-06-25

  Suggested is a cosmetic compositions comprising (a) a crosspolymer obtained from copolymerisation of at least two different polyols and at least one dicarboxylic acid and (b) at least one fragrance.

  建议的是一种化妆品组合物，包括 (a) 由至少两种不同的多元醇和至少一种二羧酸共聚得到的交联聚合物，以及 (b) 至少一种香料。
• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• Copper(II) triflate-catalyzed reduction of carboxylic acids to alcohols and reductive etherification of carbonyl compounds
  作者：Yin-Jie Zhang、Wissam Dayoub、Guo-Rong Chen、Marc Lemaire

  DOI：10.1016/j.tet.2012.06.080

  日期：2012.9

  protocol is described for the reduction of carboxylic acids to primary alcohols using 1,1,3,3-tetramethyldisiloxane (TMDS) and a catalytic amount of Cu(OTf)2. Aliphatic as well as aromatic carboxylic acids are reduced in high selectivity and good yields. TMDS/Cu(OTf)2 has also been found to be an efficient catalytic reducing system for the preparation of symmetrical ethers from carbonyl compounds under

  描述了一种使用1,1,3,3-四甲基二硅氧烷（TMDS）和催化量的Cu（OTf）2将羧酸还原为伯醇的方案。脂肪族和芳香族羧酸以高的选择性和良好的产率降低。还发现TMDS / Cu（OTf）2是一种有效的催化还原体系，用于在温和条件下从羰基化合物制备对称醚。
• COMPOSITION COMPRISING PRECURSOR FOR VOLATILES
  申请人：Henkel AG & Co. KGaA

  公开号：US20200224120A1

  公开（公告）日：2020-07-16

  A detergent, cleaning, fabric softener or cosmetic composition comprising a compound based on 1-Aza-3,7-dioxabicyclo[3.3.0]octane (bicyclic oxazolidine derivative) substituted with 3,7-dimethyl-1,6-nonyldien represented by formula (I) is disclosed.

  一种洗涤剂、清洁剂、织物柔软剂或化妆品组合物，包含基于1-Aza-3,7-dioxabicyclo[3.3.0]octane（双环氧杂环丁烷衍生物）的化合物，该化合物被3,7-二甲基-1,6-壬二烯取代，其代表性结构如式(I)所示。