methyl 4-oxo-5-(trimethylsilylmethyl)hex-5-enoate | 137190-13-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: methyl 4-oxo-5-(trimethylsilylmethyl)hex-5-enoate
• CAS: 137190-13-7
• 化学式: C₁₁H₂₀O₃Si
• 分子量: 228.363
• InChiKey: NCRVANPOPPMERZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15.0
• 可旋转键数：
  6.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  43.37
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  2-trimethylstannyl-3-trimethylsilylpropene 、 丁二酸单甲酯酰氯 在 trans-benzyl(chloro)-bis(triphenylphosphine)palladium(II) 作用下， 以 氯仿 为溶剂， 反应 48.0h， 以60%的产率得到methyl 4-oxo-5-(trimethylsilylmethyl)hex-5-enoate
  参考文献：
  名称：

  Synthesis of functionalized allylsilanes via palladium-catalyzed cross-coupling of 2-stannyl-3-silylpropene with organic halides.

  摘要：

  Allylsilanes bearing the various functionalities were prepared from the palladium-catalyzed cross-coupling reactions of 2-trimethylstannyl-3-trimethylsilylpropene with acid chlorides and with aryl halides.

  DOI：

  10.1016/s0040-4039(00)92165-8

文献信息

• Synthesis of functionalized allylsilanes via palladium-catalyzed cross-coupling of 2-stannyl-3-silylpropene with organic halides.
  作者：Kyung-Tae Kang、Soung Sin Kim、Jae Chul Lee

  DOI：10.1016/s0040-4039(00)92165-8

  日期：1991.1

  Allylsilanes bearing the various functionalities were prepared from the palladium-catalyzed cross-coupling reactions of 2-trimethylstannyl-3-trimethylsilylpropene with acid chlorides and with aryl halides.