Decyl-p-tolylether | 60010-58-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: Decyl-p-tolylether
• 英文别名: 1-Decoxy-4-methylbenzene
• CAS: 60010-58-4
• 化学式: C₁₇H₂₈O
• mdl: MFCD00968650
• 分子量: 248.409
• InChiKey: ZSRAKZSBHXPGKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  18
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.647
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Decyl-p-tolylether 在 N-溴代丁二酰亚胺(NBS) 、 过氧化苯甲酰 作用下， 以 四氯化碳 为溶剂， 以30%的产率得到p-Decyloxybenzylbromid
  参考文献：
  名称：

  Bicephalic amphiphile architecture affects antibacterial activity

  摘要：

  A series of cationic amphiphiles, each with an aromatic core, was prepared and investigated for antimicrobial properties. The synthesized amphiphiles in this study are bicephalic (double-headed) in that they each possess two trimethylammonium head groups and a single linear alkoxy tail. Minimum inhibitory and minimum bactericidal concentrations of these amphiphiles were in the low micromolar range. Antimicrobial activities are highly sensitive to the chain length of the hydrophobic region, and modestly reliant on the relative positioning of the head groups on the aromatic core. These trends were more pronounced in time kill assays, wherein longer chain compounds required significantly shorter times to completely kill bacteria. Microscopy suggested that the mode of cell death was lysis. Strong inhibition was observed with both biscationic compounds and monocationic comparisons against Gram-positive bacteria: only biscationic amphiphiles maintained good activity versus the Gram-negative bacteria tested. These observations provide direction for future antimicrobial structural investigations. (C) 2011 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2011.06.026
• 作为产物：
  描述：

  对甲酚 、 癸基溴 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 反应 48.0h， 以92%的产率得到Decyl-p-tolylether
  参考文献：
  名称：

  Bicephalic amphiphile architecture affects antibacterial activity

  摘要：

  A series of cationic amphiphiles, each with an aromatic core, was prepared and investigated for antimicrobial properties. The synthesized amphiphiles in this study are bicephalic (double-headed) in that they each possess two trimethylammonium head groups and a single linear alkoxy tail. Minimum inhibitory and minimum bactericidal concentrations of these amphiphiles were in the low micromolar range. Antimicrobial activities are highly sensitive to the chain length of the hydrophobic region, and modestly reliant on the relative positioning of the head groups on the aromatic core. These trends were more pronounced in time kill assays, wherein longer chain compounds required significantly shorter times to completely kill bacteria. Microscopy suggested that the mode of cell death was lysis. Strong inhibition was observed with both biscationic compounds and monocationic comparisons against Gram-positive bacteria: only biscationic amphiphiles maintained good activity versus the Gram-negative bacteria tested. These observations provide direction for future antimicrobial structural investigations. (C) 2011 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2011.06.026

文献信息

• [EN] ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME<br/>[FR] COMPOSÉS ARYLE ET POLYMÈRES ET PROCÉDÉS DE FABRICATION ET D'UTILISATION CORRESPONDANTS
  申请人：UNIV NEVADA RENO

  公开号：WO2016149633A1

  公开（公告）日：2016-09-22

  Disclosed herein are embodiments of aryl compounds and polymers thereof that are made using methods that do not require harsh conditions or expensive reagents. The methods disclosed herein utilize precursor compounds that can be polymerized to form polycyclic aromatic hydrocarbons and polymers, such as carbon-based polymers like nanostructures (e.g., graphene or graphene-like nanoribbons).

  本文披露了一种芳基化合物及其聚合物的实施例，这些实施例是通过不需要苛刻条件或昂贵试剂的方法制备的。本文披露的方法利用可以聚合形成多环芳烃和聚合物的前体化合物，例如碳基聚合物，如纳米结构（例如石墨烯或类石墨烯纳米带）。
• [EN] A PROCESS FOR THE PREPARATION OF UV ABSORBERS<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ABSORBEURS UV
  申请人：BASF SE

  公开号：WO2020144094A1

  公开（公告）日：2020-07-16

  The presently claimed invention relates to a novel, highly efficient and general process for the preparation of UV absorbers.

  目前所声称的发明涉及一种新颖、高效和通用的紫外线吸收剂制备过程。
• [EN] A PROCESS FOR THE PREPARATION OF TRIAZINE INTERMEDIATES AND A PROCESS FOR THE PREPARATION OF UV ABSORBERS THEREOF<br/>[FR] PROCÉDÉ DE PRÉPARATION D'INTERMÉDIAIRES DE TRIAZINE ET PROCÉDÉ DE PRÉPARATION D'ABSORBEURS UV ASSOCIÉS
  申请人：BASF SE

  公开号：WO2020144093A1

  公开（公告）日：2020-07-16

  The presently claimed invention relates to a novel, highly efficient and general process for the preparation of the triazine intermediates and their use in the preparation of UV absorbers.

  目前所声称的发明涉及一种新颖、高效和通用的三嗪中间体制备过程及其在制备紫外线吸收剂中的应用。
• Arylindenopyridines and related therapeutic and prophylactic methods
  申请人：——

  公开号：US20040082578A1

  公开（公告）日：2004-04-29

  This invention provides novel arylindenopyridines of the formula: 1 and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing Adensine A2a receptors or reducing PDE activity in appropriate cells. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.

  本发明提供了新型的芳基茚莽啶化合物的公式1及其制成的药物组合物，用于治疗通过拮抗腺苷A2a受体或在适当的细胞中减少PDE活性而改善的疾病。本发明还提供了使用该药物组合物的治疗和预防方法。
• METHODS FOR THE SYNTHESIS OF MODULAR POLY(PHENYLENEETHYNYLENES) AND FINE TUNING THE ELECTRONIC PROPERTIES THEREOF FOR THE FUNCTIONALIZATION OF NANOMATERIALS
  申请人：Ait-Haddou Hassan

  公开号：US20120259073A1

  公开（公告）日：2012-10-11

  Poly(aryleneethynylene) polymers for exfoliating and dispersing/solubilizing nanomaterial are provided herein. The poly(aryleneethynylene) polymers have unit monomer portions, each monomer portion having at least one electron donating substituent thereby forming an electron donor monomer portion, or at least one electron withdrawing substituent thereby forming an electron accepting monomer portion. Such polymers exfoliate and disperse nanomaterial without presonication of the nanomaterial.

  本文提供了用于剥离、分散/溶解纳米材料的聚(芳基乙炔)聚合物。聚(芳基乙炔)聚合物具有单体单元部分，每个单体部分具有至少一个电子给体取代基，从而形成电子给体单体部分，或者至少一个电子受体取代基，从而形成电子受体单体部分。这样的聚合物可以在不进行纳米材料超声处理的情况下剥离和分散纳米材料。