4-bromo-2-methyl-N-(2,2,2-trifluoroethyl)benzamide | 864725-41-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-bromo-2-methyl-N-(2,2,2-trifluoroethyl)benzamide
• 英文别名: 4-bromo-2-methyl-N-(2,2,2-trifluoroethyl)-benzoic acid amide；4-Bromo-2-methyl-N-(2,2,2-trifluoro-ethyl)-benzamide
• CAS: 864725-41-7
• 化学式: C₁₀H₉BrF₃NO
• 分子量: 296.087
• InChiKey: GZDNDRHHNXGAIW-UHFFFAOYSA-N

物化性质

• 沸点：
  304.3±42.0 °C(Predicted)
• 密度：
  1.517±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-bromo-2-methyl-N-(2,2,2-trifluoroethyl)benzamide 、 4-(3,5-dichlorophenyl)-4-(trifluoromethyl)-1,5-dihydropyrazole 在 palladium diacetate 、 caesium carbonate 、 2-二环己基磷-2,4,6-三异丙基联苯 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以52%的产率得到4-[4-(3,5-dichlorophenyl)-4-(trifluoromethyl)-3H-pyrazol-2-yl]-2-methyl-N-(2,2,2-trifluoroethyl)benzamide
  参考文献：
  名称：

  [EN] PYRAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS
  [FR] DÉRIVÉS DE PYRAZOLINE EN TANT QUE COMPOSÉS INSECTICIDES

  摘要：

  本发明涉及式(I)的化合物，其中P从P1和P2中选择，或P和R5一起是P3，或P是从H1到H9中选择的杂环H，其中Y1，Y2和Y3独立地是C-H，C-R5或氮; G1，G2，G3，Z，R1，R2，R3，R4，R5，R6a，R6b，R7，R8，R9，R10，R11，p，n和k如权利要求所定义。本发明还涉及控制昆虫、螨虫、线虫或软体动物的方法，包括向害虫、害虫的场所或易受攻击的植物施用式(I)的化合物的杀虫、杀螨、杀线虫或杀软体动物的有效量。

  公开号：

  WO2014114250A1
• 作为产物：
  描述：

  2,2,2-三氟乙基胺 、 4-溴-2-甲基苯甲酸 在 1-[3-(diethylamino)propyl]-3-ethylcarbodiimide hydrochloride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 1.5h， 生成 4-bromo-2-methyl-N-(2,2,2-trifluoroethyl)benzamide
  参考文献：
  名称：

  ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT

  摘要：

  公开号：

  EP1731512B9

文献信息

• Isoxazoline-substituted benzamide compound and pesticide
  申请人：Mita Takeshi

  公开号：US20070066617A1

  公开（公告）日：2007-03-22

  An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: wherein A 1 , A 2 and A 3 independently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., X is halogen atom, C 1 -C 6 haloalkyl, etc., Y is halogen atm, C 1 -C 6 alkyl, etc., R 1 is C 1 -C 12 alkyl arbitrarily substituted with R 16 , C 3 -C 2 alkenyl, arbitrarily substituted with R 16 is oxygen atom or sulfur atom, —N(R 20 )R 19 , etc., R 2 is hydrogen atom, C 1 -C 4 alkoxy C 1 -C 6 alkyl, etc., R 3 is C 1 -C 6 haloalkyl, etc., R 16 is halogen atom, cyano, phenyl substituted with (Z) p1 , D-1 to D-60, E-1 to E-49, etc., R 19 is phenyl, phenyl substituted with (Z) p1 , etc., R 20 is hydrogen atom, C 1 -C 6 alkyl, etc., Z is halogen atom, nitro, C 1 -C 4 alkoxy, etc., D-1 to D-60 are 5- or 6-membered aromatic heterocyclic rings, E-1 to E-49 are 5- or 6-membered saturated heterocyclic rings, m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

  一种公式（1）所示的异噁唑基取代的苯甲酰胺化合物或其盐： 其中A1，A2和A3独立地为碳原子或氮原子，G为苯环等，X为卤素原子，C1-C6卤代烷基等，Y为卤素原子，C1-C6烷基等，R1是任意取代的C1-C12烷基，或者任意取代的C3-C2烯基，取代基为R16，R16是卤素原子，氰基，苯基取代的（Z）p1，D-1至D-60，E-1至E-49等，R2为氢原子，C1-C4烷氧基C1-C6烷基等，R3为C1-C6卤代烷基等，R19为苯基，苯基取代的（Z）p1等，R20为氢原子，C1-C6烷基等，Z为卤素原子，硝基，C1-C4烷氧基等，D-1至D-60为5-或6-成员芳香杂环环，E-1至E-49为5-或6-成员饱和杂环，m为0至5的整数，n为0至4的整数，p1为1至5的整数。包含这些化合物的杀虫剂。
• ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE
  申请人：Mita Takeshi

  公开号：US20090312330A1

  公开（公告）日：2009-12-17

  An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: wherein A 1 , A 2 and A 3 independently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., X is halogen atom, C 1 -C 6 haloalkyl, etc., Y is halogen atm, C 1 -C 6 alkyl, etc., R 1 is C 1 -C 12 alkyl arbitrarily substituted with R 16 , C 3 -C 12 alkenyl, arbitrarily substituted with R 16 is oxygen atom or sulfur atom, —N(R 20 )R 19 , etc., R 2 is hydrogen atom, C 1 -C 4 alkoxy C 1 -C 6 alkyl, etc., R 3 is C 1 -C 6 haloalkyl, etc., R 16 is halogen atom, cyano, phenyl substituted with (Z) p1 , D-1 to D-60, E-1 to E-49, etc., R 19 is phenyl, phenyl substituted with (Z) p1 , etc., R 20 is hydrogen atom, C 1 -C 6 alkyl, etc., Z is halogen atom, nitro, C 1 -C 4 alkoxy, etc., D-1 to D-60 are 5- or 6-membered aromatic heterocyclic rings, E-1 to E-49 are 5- or 6-membered saturated heterocyclic rings, m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

  一种公式（1）的异氧杂环取代苯甲酰胺化合物或其盐： 其中，A1，A2和A3独立地是碳原子或氮原子，G是苯环等，X是卤素原子，C1-C6卤代烷基等，Y是卤素原子，C1-C6烷基等，R1是任意取代R16的C1-C12烷基，任意取代R16的C3-C12烯基，是氧原子或硫原子，-N（R20）R19等，R2是氢原子，C1-C4烷氧基C1-C6烷基等，R3是C1-C6卤代烷基等，R16是卤素原子，氰基，苯基，其上取代有（Z）p1，D-1至D-60，E-1至E-49等，R19是苯基，其上取代有（Z）p1等，R20是氢原子，C1-C6烷基等，Z是卤素原子，硝基，C1-C4烷氧基等，D-1至D-60是5-或6-成员芳香杂环，E-1至E-49是5-或6-成员饱和杂环，m是0至5的整数，n是0至4的整数，p1是1至5的整数。含有这些化合物的杀虫剂。
• PYRAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：US20150353532A1

  公开（公告）日：2015-12-10

  The present invention relates to compounds of formula (I) wherein P is selected from P1 and P2, or P and R 5 together are P3 or P is a heterocycle H, selected from H1 to H9 wherein Y 1 , Y 2 and Y 3 are independently of each other C—H, C—R 5 , or nitrogen; and G 1 , G 2 , G 3 , Z, R 1 , R 2 , R 3 , R 4 , R 5 , R 6a , R 6b , R 7 , R 8 , R 9 , R 10 , R 11 , p, n and k are as defined in the claims. The invention also relates to methods of controlling insects, acarines, nematodes or molluscs which comprises applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I).

  本发明涉及式（I）的化合物，其中P选自P1和P2，或P和R5一起是P3，或P是从H1到H9中选择的杂环H，其中Y1、Y2和Y3分别独立地为C-H、C-R5或氮；以及G1、G2、G3、Z、R1、R2、R3、R4、R5、R6a、R6b、R7、R8、R9、R10、R11、p、n和k如权利要求所定义。本发明还涉及控制昆虫、螨、线虫或软体动物的方法，包括向害虫、害虫的位置或易受害虫侵袭的植物施加式（I）的杀虫、杀螨、杀线虫或杀软体动物有效量的化合物。
• Pyrazoline derivatives as insecticidal compounds
  申请人：Syngenta Participations AG

  公开号：US10287281B2

  公开（公告）日：2019-05-14

  The present invention relates to compounds of formula I wherein P is selected from P1 and P2, or P and R5 together are P3 or P is a heterocycle H, selected from H1 to H9 wherein Y1, Y2, and Y3 are independently of each other C—H, C—R5, or nitrogen; and G1, G2, G3, Z, R1, R2, R3, R4, R5, R6a, R6b, R7, R8, R9, R10, R11, p, n and k are as defined in the claims. The invention also relates to methods of controlling insects, acarines, nematodes or molluscs which comprises applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula I.

  本发明涉及式 I 的化合物 式中 P 选自 P1 和 P2，或 P 和 R5 合在一起为 P3 或 P 是杂环 H，选自 H1 至 H9 其中Y1、Y2和Y3彼此独立地为C-H、C-R5或氮；以及G1、G2、G3、Z、R1、R2、R3、R4、R5、R6a、R6b、R7、R8、R9、R10、R11、p、n和k如权利要求中所定义。本发明还涉及控制昆虫、螨虫、线虫或软体动物的方法，其中包括对害虫、害虫的位点或易受害虫攻击的植物施用杀虫、杀螨、杀线虫或杀软体动物有效量的式I化合物。
• US7662972B2
  申请人：——

  公开号：US7662972B2

  公开（公告）日：2010-02-16