1-Methoxy-3-acetoxy-propanol-(2) | 89534-59-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1-Methoxy-3-acetoxy-propanol-(2)
• 英文别名: 1-acetoxy-3-methoxy-propan-2-ol；(2-Hydroxy-3-methoxypropyl) acetate
• CAS: 89534-59-8
• 化学式: C₆H₁₂O₄
• 分子量: 148.159
• InChiKey: JEDSBSJEOMARSR-UHFFFAOYSA-N

物化性质

• 沸点：
  98-99 °C
• 密度：
  1.1014 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-Methoxy-3-acetoxy-propanol-(2) 在 氯仿 、 三溴化磷 作用下， 生成 acetic acid-(2-bromo-3-methoxy-propyl ester)
  参考文献：
  名称：

  Antispasmodics. XVIII. Diphenylacetates and p-Aminobenzoates of Basic Alkoxyalkanols

  摘要：

  DOI：

  10.1021/ja01641a015
• 作为产物：
  描述：

  1-氯-3-甲氧基-2-丙醇 、 potassium acetate 生成 1-Methoxy-3-acetoxy-propanol-(2)
  参考文献：
  名称：

  Mamedov,S.; Gadzhizade,F., Journal of general chemistry of the USSR, 1963, vol. 33, p. 817 - 821

  摘要：

  DOI：

文献信息

• Regioselective acetylation of carbohydrates and diols catalyzed by tetramethyl-ammonium hydroxide in water
  作者：Yuchao Lu、Peng Wei、Yuxin Pei、Hengfu Xu、Xiaoting Xin、Zhichao Pei

  DOI：10.1039/c4gc00770k

  日期：——

  A novel method for an efficient regioselective acetylation of carbohydrates and diols in aqueous solution is described. Treatment of substrates with 1-acetylimidazole, and tetramethyl-ammonium hydroxide (TMAH) in water under mild conditions gave highly regioselective acetylation for primary hydroxyl groups. This discovery provides an eco-friendly way for selective acetylation of non-protected glycosides

  描述了一种用于在水溶液中有效地对碳水化合物和二醇进行区域选择性乙酰化的新方法。在温和的条件下，在水中用1-乙酰基咪唑和氢氧化四甲基铵（TMAH）处理底物，可得到伯羟基的高度区域选择性乙酰化。该发现为水中非保护的糖苷和二醇的选择性乙酰化提供了一种环保的方法，避免了使用有毒有机溶剂和避免对仲羟基进行预保护的必要性。
• MBA-cross-linked poly(N-vinyl-2-pyrrolidone)/ferric chloride macromolecular coordination complex as a novel and recyclable Lewis acid catalyst: Synthesis, characterization, and performance toward for regioselective ring-opening alcoholysis of epoxides
  作者：Ali Rahmatpour、Maryam Zamani

  DOI：10.1016/j.reactfunctpolym.2021.105032

  日期：2021.11

  (PNVP/FeCl3) as an efficient and recyclable polymeric Lewis acid catalyst was appropriately probed in the regio-and stereoselective nucleophilic ring opening of various epoxides with various alcohols in excellent yields with TOF up to 182.48 h−1 without generating any waste. The activity data indicate that this heterogeneous catalyst is very active and could be easily recovered, and reused at least

  一种新型的高分子-金属配位络合物，MBA交联PNVP /的FeCl 3的物质通过的水不耐受氯化铁固定（制造在多孔交联聚Ñ乙烯基-2-吡咯烷酮）的载体珠作为大分子配体或N-乙烯基-2-吡咯烷酮（NVP）和作为交联剂的N，N'-亚甲基双丙烯酰胺（MBA）在水中悬浮自由基共聚制备的载体。得到的PNVP/FeCl 3用紫外/可见光和 FT-IR 光谱、TGA、FE-SEM、EDX 和 ICP 技术表征。这种氯化铁的异质化版本是高度不耐受氯化铁的一种方便且安全的替代品。(PNVP/FeCl 3 ) 作为一种高效且可回收的聚合路易斯酸催化剂的催化性能在各种环氧化物与各种醇的区域和立体选择性亲核开环方面进行了适当的探索，TOF 高达 182.48 h -1 且没有生成任何浪费。活性数据表明，这种多相催化剂非常活泼，易于回收，可重复使用至少 6 次，活性没有明显损失，表明其在实验条件下是稳定的。
• Highly regioselective ring opening of epoxides with alcohols catalyzed by organotin phosphate condensates
  作者：Junzo Otera、Yukari Yoshinaga、Kazuhisa Hirakawa、Tetsuya Nakata

  DOI：10.1016/s0040-4039(00)98156-5

  日期：1985.1

  Organotin phosphate condensates proved to catalyze the ring opening reaction of epoxides with alcohols in a highly regioselective manner.

  磷酸有机锡缩合物被证明以高度区域选择性的方式催化环氧化物与醇的开环反应。
• SALT, PHOTORESIST COMPOSITION AND METHOD FOR PRODUCING PHOTORESIST PATTERN
  申请人：ICHIKAWA Koji

  公开号：US20130040239A1

  公开（公告）日：2013-02-14

  A salt represented by formula (I): wherein Q 1 , Q 2 , L 1 , W, and Z + are defined in the specification.

  由公式（I）代表的一种盐：其中Q1、Q2、L1、W和Z+在说明书中定义。
• EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD FOR PREPARING THE SAME, COMPOSITION INCLUDING THE SAME, CURED PRODUCT MADE FROM THE COMPOSITION, AND USE OF THE COMPOSITION
  申请人：KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY

  公开号：US20150247033A1

  公开（公告）日：2015-09-03

  Provided are an alkoxysilylated epoxy compound, a composite of which exhibits good heat resistance properties, particularly low CTE and increased glass transition temperature, and a cured product thereof exhibits good flame retardancy and composition of which does not require additional silane coupling agent, a method for preparing the same and a composition and a cured product including the same. An alkoxysilylated epoxy compound including at least one alkoxysilyl group and at least two epoxy groups, a method for preparing the same by epoxide ring-opening reaction of starting material and alkoxysilylation, an epoxy composition including the epoxy compound, and a cured product and a use of the composition are provided. Since chemical bonds may be formed between alkoxysilyl group and filler and between alkoxysilyl groups, chemical bonding efficiency of the composite may be improved. Thus, the composite exhibits good heat resistance properties and the cured product exhibits good flame retardancy.

  提供一种含有烷氧基硅烷基化环氧化合物，其复合材料具有良好的耐热性能，特别是低CTE和增加的玻璃转变温度，其固化产物具有良好的阻燃性能，其组成物不需要额外的硅烷偶联剂，提供了一种制备该化合物的方法，以及包括该化合物的组合物和固化产物。提供了一种含有至少一个烷氧基硅烷基团和至少两个环氧基团的烷氧基硅烷基化环氧化合物，通过起始材料的环氧基开环反应和烷氧基硅烷基化的方法来制备该化合物，一种包括该环氧化合物的环氧树脂组合物，以及固化产物和使用该组合物的用途。由于烷氧基硅烷基团与填料之间以及烷氧基硅烷基团之间可能形成化学键，复合材料的化学键合效率可能得到提高。因此，该复合材料具有良好的耐热性能，固化产物具有良好的阻燃性能。