Milchsaeure-<2-hydroxy-propylester> | 14396-73-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Milchsaeure-<2-hydroxy-propylester>
• 英文别名: Milchsaeure-(2-hydroxy-propylester)；2-Hydroxypropyl 2-hydroxypropanoate
• CAS: 14396-73-7
• 化学式: C₆H₁₂O₄
• 分子量: 148.159
• InChiKey: RJQYORITUSNLNB-UHFFFAOYSA-N

物化性质

• 沸点：
  88-90 °C(Press: 5 Torr)
• 密度：
  1.0900 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Milchsaeure-<2-hydroxy-propylester> 、 DL-甘油醛 在 乳酸 作用下， 以 水 为溶剂， 生成 Milchsaeure-<2-(1,2,3-trihydroxy-propyloxy)-propylester>
  参考文献：
  名称：

  Razuvaev,G.A. et al., Journal of Organic Chemistry USSR (English Translation), 1966, vol. 2, p. 2003 - 2006

  摘要：

  DOI：
• 作为产物：
  描述：

  methyloxirane 在 双氧水 作用下， 生成 Milchsaeure-<2-hydroxy-propylester>
  参考文献：
  名称：

  Razuvaev,G.A. et al., Journal of Organic Chemistry USSR (English Translation), 1966, vol. 2, p. 2003 - 2006

  摘要：

  DOI：

文献信息

• [EN] A PROCESS FOR PREPARATION OF AMIDES AND ESTHERS OF 2-((2-HYDROXYPANOYL)OXY)PROPANOIC ACID<br/>[FR] PROCÉDÉ DE PRÉPARATION D'AMIDES ET D'ESTHERS DE L'ACIDE 2-((2-HYDROXYPANOYL)OXY)PROPANOÏQUE
  申请人：UNIV PARDUBICE

  公开号：WO2020125823A1

  公开（公告）日：2020-06-25

  The present invention describes method of preparation of esters or amides of lactyl lactates of general formula (I), where Z denotes to group of R-O or RR-N and R represent alkyl, aryl or H from lactide and the lactide is in contact with a hydrocarbyl alcohol and a hydrolyzable halide in a non-chlorinated organic solvent, or an amine initiated by a hydrolysable halide or hydrogen halide solution or an ammonium hydrohalide, wherein the hydrocarbyl alcohol or amine is either aliphatic or aromatic and containing 1 to 1000 carbon atoms, preferably 1 up to 150 carbon atoms, and optionally one or more, preferably 1 to 5, -CH2- groups may be replaced by -O-groups.

  本发明描述了一种制备通式（I）的乳酰乳酸酯或酰胺的方法，其中Z代表R-O或RR-N基团，R代表来自乳酸内酯的烷基、芳基或氢，而且该乳酸内酯与烃基醇和可水解卤化物在非氯有机溶剂中接触，或者在氨基引发的可水解卤化物或氢卤酸溶液或铵盐氢卤酸中接触，其中烃基醇或胺可以是脂肪族或芳香族，含有1至1000个碳原子，优选含有1至150个碳原子，并且可选地，一个或多个，优选1至5个，-CH2-基团可以被-O-基团取代。
• Method and product for skin lightening
  申请人：Unilever Home & Personal Care USA, Division of Conopco, Inc.

  公开号：US20030044362A1

  公开（公告）日：2003-03-06

  A method and cosmetic product for lightening skin is provided, the method including wiping the skin with a cosmetic towelette. Impregnated on the towelette is an alpha-hydroxy carboxylic acid or salt thereof and a sunscreen agent.

  提供一种用于美白皮肤的方法和化妆品产品，该方法包括用化妆湿巾擦拭皮肤。湿巾上浸渍有α-羟基羧酸或其盐以及防晒剂。
• APPLICATIONS OF BIOBASED GLYCOL COMPOSITIONS
  申请人：Binder Thomas Paul

  公开号：US20080103340A1

  公开（公告）日：2008-05-01

  A biobased replacement for propylene glycol and ethylene glycol derived from petrochemical sources is presented. The product mixture from the hydrogenolysis of certain polyols from biobased renewable resources may replace propylene glycol and ethylene glycol products from petrochemical sources. Applications and methods of the biobased hydrogenolysis product mixture are disclosed. The compositions and methods provide a feedstock for industrial use which has a 13 C/ 12 C isotope ratio characteristic of bioderived material.

  提出了一种基于生物的替代品，用于丙二醇和乙二醇，这些替代品源自石化来源。从基于生物可再生资源中的某些多元醇的氢解反应产生的产物混合物可以替代石化来源的丙二醇和乙二醇产品。公开了基于生物氢解产物混合物的应用和方法。这些组合物和方法提供了一个13C/12C同位素比特征为生物衍生材料的工业用原料。
• [EN] ANTIVIRAL TREATMENT<br/>[FR] TRAITEMENT ANTIVIRAL
  申请人：ECOSYNTH NV

  公开号：WO2021176010A1

  公开（公告）日：2021-09-10

  The present description relates to the use of myramistin, its derivatives and the forms thereof for treating or ameliorating infections caused by enveloped viruses, methods for preparing the compounds and pharmaceutical compositions containing such compounds. In particular the use of myramistin, its derivatives and forms for treating or ameliorating infections caused by coronaviruses. More particularly, the present description relates to the use of myramistin, its derivatives and forms thereof for treating or ameliorating Coronavirus disease 2019 (COVID-19).

  本描述涉及使用肥皂草碱、其衍生物及其形式用于治疗或改善由包膜病毒引起的感染，制备这些化合物的方法以及含有这些化合物的药物组合物。特别是使用肥皂草碱、其衍生物和形式来治疗或改善由冠状病毒引起的感染。更具体地，本描述涉及使用肥皂草碱、其衍生物及其形式来治疗或改善冠状病毒病2019（COVID-19）。
• Allantoin-containing skin cream
  申请人：——

  公开号：US20010002290A1

  公开（公告）日：2001-05-31

  An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The pH of the composition is in a range of from about 3.0 to about 6.0; preferably, the pH of the composition is from about 5.0 to about 6.0. The composition can further comprise an acidic anionic polymer. A preferred acidic anionic polymer is a carboxypolymethylene polymer. The composition can further comprise a carbohydrate polymer such as galactoarabinan, polygalactose or polyarabinose. The composition can additionally comprise other ingredients such as herbal extracts, an antioxidant component, an emollient component, a chelator, a solvent component, or a preservative component. The composition is useful as a skin protectant.

  一种含有尿囊素的皮肤霜组合物可以包括尿囊素和至少一种阴离子或非离子乳化剂，该乳化剂在水中溶解且具有亲水性。组合物的pH范围大约在3.0到6.0之间；最好是，组合物的pH范围大约在5.0到6.0之间。该组合物还可以包括酸性阴离子聚合物。首选的酸性阴离子聚合物是羧基聚甲烯聚合物。该组合物还可以包括碳水化合物聚合物，如半乳阿拉伯聚糖、聚半乳糖或聚阿拉伯糖。该组合物还可以额外包括其他成分，如草药提取物、抗氧化剂成分、润肤剂成分、螯合剂、溶剂成分或防腐剂成分。该组合物可用作皮肤保护剂。