2,3-Dimethoxy(dichloromethyl)benzene | 136269-34-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3-Dimethoxy(dichloromethyl)benzene
• 英文别名: 1-(Dichloromethyl)-2,3-dimethoxybenzene
• CAS: 136269-34-6
• 化学式: C₉H₁₀Cl₂O₂
• 分子量: 221.083
• InChiKey: DJZZMOQLXGGOHR-UHFFFAOYSA-N

物化性质

• 沸点：
  291.8±40.0 °C(Predicted)
• 密度：
  1.247±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,3-Dimethoxy(dichloromethyl)benzene 在 potassium tert-butylate 、 silica gel 作用下， 以 四氯化碳 、 乙二醇二甲醚 为溶剂， 生成 1-(1-Isopropenyl-2-methyl-propenyl)-2,3-dimethoxy-benzene
  参考文献：
  名称：

  Baird, Mark S.; Dacre, Richard; Tomkinson, Jeremy, Journal of the Chemical Society. Perkin transactions I, 1992, # 5, p. 535 - 538

  摘要：

  DOI：

文献信息

• Synthesis of new aryl-substituted methylphosphonic and methylenediphosphonic acids and their derivatives
  作者：A. A. Prishchenko、M. V. Livantsov、O. P. Novikova、L. I. Livantsova、V. S. Petrosyan

  DOI：10.1007/s11172-017-1736-5

  日期：2017.2

  Simple and versatile synthetic procedures towards new aryl-substituted hydroxymethylphosphonic and methylenediphosphonic acids via reactions of either aromatic aldehydes or their derivatives with phosphites were elaborated.

  详细阐述了通过芳香醛或其衍生物与亚磷酸酯反应制备新的芳基取代的羟甲基膦酸和亚甲基二膦酸的简单而通用的合成方法。
• Process for opening cyclopropane rings
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0432818A2

  公开（公告）日：1991-06-19

  Process for ring opening compounds of the formula in which R¹ is heteroaryl or aryl, R² is a leaving group, R³, R⁴, R⁵ and R⁶ are independently selected from hydrogen, alkyl, aralkyl, aryl, heteroaryl and alkenyl, provided that at least one of the groups R³ to R⁶ is other than hydrogen, by breaking the bond joining the carbon atom attached to R³ and the carbon atom attached to R⁶ in organic solution using silica,giving useful diene or allyl derivatives, certain of which are novel.

  式的开环化合物的工艺 其中 R¹ 为杂芳基或芳基，R² 为离去基团，R³、R⁴、R⁵ 和 R⁶ 独立选自氢、烷基、芳基、芳基、杂芳基和烯基，条件是 R³ 至 R⁶ 中至少有一个基团不是氢、在有机溶液中用二氧化硅断开连接 R³ 的碳原子和连接 R⁶ 的碳原子的键，得到有用的二烯或烯丙基衍生物，其中某些衍生物是新颖的。
• MDR reversal agents
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0634401A1

  公开（公告）日：1995-01-18

  Compounds of the general formula: wherein R₁, R₂, R₃, R₄ and R₅ are herein described, A is a straight or branched (C₂-C₁₂)alkyl or a phenyl moiety and B is a moiety of the formula: The compounds are effective in potentiating the activity of chemotherapeutic anti-cancer agents by increasing the sensitivity of multi-drug resistant cells to such chemotherapeutic agents.

  通式为 其中 R₁、R₂、R₃、R₄ 和 R₅ 如下所述，A 是直链或支链 (C₂-C₁₂)烷基或苯基，B 是式中的分子： 这些化合物通过提高耐多药细胞对抗癌化疗药物的敏感性，有效增强抗癌化疗药物的活性。
• Resin composition
  申请人：TORAY INDUSTRIES, INC.

  公开号：US10990008B2

  公开（公告）日：2021-04-27

  The present invention provides a resin composition which can result in a cured film which has chemical resistance, low stress property, and high elongation property even by a heat treatment at a low temperature. The resin composition comprising an alkali-soluble resin (a) which contains a phenol skeleton having a crosslinking group and a phenol skeleton not having a crosslinking group and which has a weight average molecular weight in the range of 1,000 to 50,000, wherein the content ratio of the phenol skeleton having a crosslinking group to the total 100% by mole of structural units of the phenol skeleton having a crosslinking group and the phenol skeleton not having a crosslinking group is in the range of 5 to 90% by mole.

  本发明提供了一种树脂组合物，即使在低温下进行热处理，也能形成具有耐化学性、低应力特性和高伸长特性的固化膜。 该树脂组合物包括碱溶性树脂 (a)，它含有具有交联基团的苯酚骨架和不具有交联基团的苯酚骨架，其重量平均分子量在 1,000 至 50,000 之间，其中具有交联基团的苯酚骨架与具有交联基团的苯酚骨架和不具有交联基团的苯酚骨架的结构单元总数的 100%（以摩尔计）的含量比在 5 至 90%（以摩尔计）之间。
• Reaction of substituted benzalchlorides with phosphorous acid esters
  作者：A. A. Prishchenko、M. V. Livantsov、O. P. Novikova、L. I. Livantsova

  DOI：10.1134/s107036320605029x

  日期：2006.5