undecyl-carbamic acid | 45164-85-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: undecyl-carbamic acid
• 英文别名: Kohlensaeure-mono-undecylamid；Undecyl-carbamidsaeure；Undecylcarbamic acid
• CAS: 45164-85-0
• 化学式: C₁₂H₂₅NO₂
• 分子量: 215.336
• InChiKey: WSNOKGKQOHFPPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  undecyl-carbamic acid 在 氯化亚砜 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 4.5h， 生成 N-formyl undecylamine
  参考文献：
  名称：

  卡巴胆碱二聚体作为毒蕈碱受体的同二价调节剂

  摘要：

  已经合成了一系列众所周知的胆碱能激动剂卡巴胆碱的同型二聚体，显示了通过可变长度的亚甲基链对称连接的两个激动剂单元。已经通过平衡结合研究对新化合物在CHO细胞中表达的五个克隆毒蕈碱受体（hM1-5）进行了测试，通过将亚甲基单元的数量增加到7和9来显示亲和力的增加。在几内亚的功能性实验猪回肠和对CHO细胞上hM1，hM2和hM3上ERK1 / 2磷酸化的评估表明，新化合物具有毒蕈碱拮抗特性。动力学结合研究表明，某些被测化合物能够减慢NMS的解离速率，表明存在双位点行为。在hM1和hM2受体上进行的对接模拟

  DOI：

  10.1016/j.bcp.2016.03.012

文献信息

• Active agent delivery systems and methods for protecting and administering active agents
  申请人：New River Pharmaceuticals Inc.

  公开号：US20040063628A1

  公开（公告）日：2004-04-01

  The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.

  本发明涉及活性物质输送系统，更具体地涉及包含氨基酸，作为单个氨基酸或肽的组成部分，与活性物质共价连接的组合物和用于给予共轭活性物质组合物的方法。
• Probing the supramolecular assembly in solid, solution and gel phase in uriede based thiazole derivatives and its potential application as iodide ion sensor
  作者：Ajaykumar M Patel、Debes Ray、Vinod K Aswal、Amar Ballabh

  DOI：10.1016/j.molliq.2022.119763

  日期：2022.9

  series of thiazole-urea-aliphatic chain-based compounds (1–7) were designed and synthesized using the principle of Crystal Engineering. The aliphatic alkyl chain of compounds was varied to obtain the delicate hydrophobic-hydrophilic balance between solute–solvent molecules required to attain the supramolecular gelation. Interestingly, all the compounds turned out to be excellent gelators for polar

  使用晶体工程原理设计和合成了一系列简单的噻唑-脲-脂肪链基化合物 (1-7)。改变化合物的脂肪族烷基链以获得实现超分子凝胶化所需的溶质-溶剂分子之间的精细疏水-亲水平衡。有趣的是，所有化合物都被证明是极好的极性溶剂凝胶剂，包括水与醇和乙腈的混合物。为了深入了解分子在固态、溶液和凝胶相中的堆积，采用了各种物理化学技术，例如 SANS、SEM、PXRD、DFT 计算等。化合物 1 在溶液相中的紫外-可见光谱测量是进行建立阴离子传感能力。
• Physostigmine derivatives with acetylcholinesterase inhibition properties, and the relative production process
  申请人：CONSIGLIO NAZIONALE DELLE RICERCHE

  公开号：EP0154864A1

  公开（公告）日：1985-09-18

  Physostigmine derivatives with acetylcholinesterase inhibition properties, of general formula: in which R can be a linear alkyl of general formula -(CH2)n-CH3 where n varies from 1 to 19, a branched alkyl, a cyclic alkyl or an aryl, and the relative production process.

  通式如下的具有乙酰胆碱酯酶抑制特性的 Physostigmine 衍生物： 其中R可以是通式为-(CH2)n-CH3（其中n为1至19）的直链烷基、支链烷基、环状烷基或芳基，以及相关的生产工艺。
• WATER-SOLUBLE AZO COMPOUND OR SALT THEREOF, INK COMPOSITION, AND COLORED MATTER
  申请人：Morita Ryoutarou

  公开号：US20110216117A1

  公开（公告）日：2011-09-08

  Disclosed is a water-soluble azo compound represented by formula (1) or a salt thereof, which functions as a yellow dye having a high print density suitable for inkjet recording. Matter recorded by using the water-soluble azo compound or a salt thereof has high fastness in various fields, and an ink composition prepared by using the water-soluble azo compound or a salt thereof has excellent storage stability. An ink composition containing the water-soluble azo compound or a salt thereof is also disclosed. In formula (1), R represents a hydrogen atom or the like; n represents an integer of 1-3; m represents 1 or 2; x represents an integer of 2-4; and group A represents a carboxy-substituted C 1 -C 20 aliphatic amino group, a sulfo-substituted C 1 -C 3 aliphatic amino group, a substituted or unsubstituted aromatic amino group, a substituted or unsubstituted aryl C 1 -C 4 alkylamino group, or the like.
• US4831155A
  申请人：——

  公开号：US4831155A

  公开（公告）日：1989-05-16