N-(4-allylphenyl)acetamide | 104699-52-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-allylphenyl)acetamide
• 英文别名: acetic acid-(4-allyl-anilide)；Essigsaeure-(4-allyl-anilid)；N-(4-prop-2-enylphenyl)acetamide
• CAS: 104699-52-7
• 化学式: C₁₁H₁₃NO
• 分子量: 175.23
• InChiKey: MZCVZUZNHFPSLY-UHFFFAOYSA-N

物化性质

• 熔点：
  91-92 °C(Solv: ethanol (64-17-5); water (7732-18-5))
• 沸点：
  338.9±21.0 °C(Predicted)
• 密度：
  1.049±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  乙酸烯丙酯 、 4'-溴乙酰苯胺 在 (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride 六正丁基二锡 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 以69%的产率得到N-(4-allylphenyl)acetamide
  参考文献：
  名称：

  钯催化的交叉偶联反应：芳基溴化物与乙酸烯丙酯的直接烯丙基化

  摘要：

  在六正丁基二锡存在下，各种芳基溴化物与乙酸烯丙酯进行钯催化的交叉偶联反应，以很高的收率得到烯丙基化的产物。

  DOI：

  10.1016/s0040-4039(00)99026-9

文献信息

• Palladium-catalyzed cross-coupling reaction of allyl acetates with pinacol aryl- and vinylboronates
  作者：Giorgio Ortar

  DOI：10.1016/s0040-4039(03)00980-8

  日期：2003.6

  Pinacol boronates 2 couple efficiently with allyl acetates 1 in the presence of a palladium catalyst prepared in situ from PdCl2 and TFP to give the coupled products 3 in moderate to good yields under mild conditions.

  频哪醇硼酸酯2有效耦合用烯丙基乙酸盐1在原位制备的PdCl从钯催化剂的存在下2和TFP，得到偶联产物3在中度至温和的条件下良好的产率。
• Nickel-catalyzed reductive allylation of aryl bromides with allylic acetates
  作者：Xiaozhan Cui、Shulin Wang、Yuwei Zhang、Wei Deng、Qun Qian、Hegui Gong

  DOI：10.1039/c3ob40232k

  日期：——

  This paper highlights Ni-catalyzed allylation of electron-rich aryl bromides with a variety of substituted allylic carbonates using zinc as the terminal reductant, affording E-alkenes regioselectively in good to excellent yields by the addition of aryl to the less hindered allylic carbon. The electron-deficient aryl bromides and chlorides are also highly efficient coupling partners.

  本文重点介绍了富锌电子富集的芳基溴与各种取代的烯丙基碳酸酯的镍催化的烯丙基化反应，并使用锌作为末端还原剂，通过向受阻较弱的烯丙基碳中添加芳基，可以选择性地以优异的产率提供高选择性的E-烯烃。缺电子的芳基溴化物和氯化物也是高效的偶联伙伴。
• LINEAR (PER) FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF
  申请人：SOLVAY SPECIALTY POLYMERS ITALY S.P.A.

  公开号：US20140243547A1

  公开（公告）日：2014-08-28

  The present invention relates to mono- or bi-functional (per)fluoropolyethers comprising a linear (per)fluoropolyether chain having two ends, wherein one or two ends contain —CF(CF 3 )COF groups, to a process for preparing them and to their use as precursors in the preparation of further functionalised (per)fluoropolyethers. The invention also relates to these further functionalised (per)fluoropolyethers.

  本发明涉及具有线性（per）氟聚醚链的单功能或双功能（per）氟聚醚，其具有两个末端，其中一个或两个末端含有—CF（CF3）COF基团，以及其制备过程和作为前体物在制备进一步功能化（per）氟聚醚中的应用。本发明还涉及这些进一步功能化的（per）氟聚醚。
• CROSS-LINKERS FOR CROSS-LINKABLE OPTICAL POLYCARBONATES
  申请人：Akzo Nobel N.V.

  公开号：EP0934266A1

  公开（公告）日：1999-08-11
• Peroxidic Perflouropolyethers
  申请人：MARCHIONNI Giuseppe

  公开号：US20080194881A1

  公开（公告）日：2008-08-14

  Peroxidic perfluoropolyethers having formula: X 1 —O(CF 2 O) n1 (CF 2 CF 2 O) m1 (CF 2 (CF 2 ) z CF 2 O) p1 (O) h —X 2 (I) wherein: X 1 and X 2 , equal to or different from each other, are chain end groups selected among —CF 2 COF, —COF, —SO 2 F; n1, m1, p1 and h are integers such that the number average molecular weight is in the range 700-100,000; z=1 or 2; with the proviso that: the m1/n1 ratio is between 0.2 and 10; the p1/(n1+m1) ratio is lower than 0.05; the h/(n1+m1+p1) ratio is such that the PO content, defined as grams of active oxygen/100 g of compound, is in the range 0.8-4.5, preferably 1.4-3.8; the perfluorooxyalkylene units being statistically distributed along the polymeric chain.