bis(tetrahydrofuryl-2)sulfide | 62308-52-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: bis(tetrahydrofuryl-2)sulfide
• 英文别名: 2,2'-Sulfanediylbis(oxolane)；2-(oxolan-2-ylsulfanyl)oxolane
• CAS: 62308-52-5
• 化学式: C₈H₁₄O₂S
• 分子量: 174.264
• InChiKey: FISZYFQVNYZZSW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  43.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,3-二氢呋喃 在 硫化氢 作用下， 生成 bis(tetrahydrofuryl-2)sulfide
  参考文献：
  名称：

  Sulfur-containing flavoring agents

  摘要：

  揭示了具有一般式##STR1##的新化合物，其中X和Y为氧或硫，R.sub.1、R.sub.2、R.sub.3和R.sub.4为氢或较低的烷基基团。这些化合物在各种调味应用中很有用。

  公开号：

  US04120985A1

文献信息

• Pharmaceutical compositions containing thio-dioxolane derivatives having mucolytic activity
  申请人：PROTER S.p.A.

  公开号：EP0288871A3

  公开（公告）日：1990-05-16

  The present invention relates to pharmaceutical compositions contaning thiodioxolane derivatives having an interesting mucolytic activity, and to a process for the preparation of said thiodioxolane derivatives of the general structural formula in which the carbon atom marked with an asterisk indicates a asimmetry center in the molecule, X represents an hydroxy group or -SRʺ and Rʺ is hydrogen or a suitable acylic radical, R rapresents hydrogen, a lower alkyl, a lower hydroxy alkyl, or phenyl, Rʹ represents a lower alkyl, a lower hydroxy alkyl, phenyl, -(CH₂)nSRʺ where n is a whole number between 1 and 3 and Rʺ has the above indicated meaning, with condition that X and Rʹ can never be both type of groups.

  本发明涉及含有具有有趣的粘液溶解活性的硫代二氧兰衍生物的制药组合物，以及制备具有一般结构式的硫代二氧兰衍生物的过程，其中用星号标记的碳原子表示分子中的不对称中心，X表示羟基或-SRʺ，其中Rʺ是氢或适当的脂肪基，R表示氢，较低的烷基，较低的羟基烷基或苯基，Rʹ表示较低的烷基，较低的羟基烷基，苯基，-(CH₂)nSRʺ，其中n是1到3之间的整数，Rʺ具有上述所指的含义，条件是X和Rʹ永远不能同时是一种类型的基团。
• PROCESS FOR PRODUCING FINE ORGANOMETALLIC PARTICLES AND CATALYST FOR POLYMERIZATION
  申请人：Nippon Shokubai Co., Ltd.

  公开号：EP0990657A1

  公开（公告）日：2000-04-05

  The present invention provides: a production process for a polyalkylene oxide with fast polymerization reaction rate and good production efficiency; a catalyst for polymerization and a dispersion thereof which are effective for the above production process for a polymer such as polyalkylene oxide; and an organometallic fine particle and a production process therefor, which particle is, for example, useful as the above catalyst for polymerization. In a means therefor, a material such as an aliphatic polyol is reacted upon an organometallic compound in a micelle as the reaction field, thus preparing a hyperfine particle, which is used as a catalyst for polymerization of ionic-polymerizable monomers mainly including a cyclic ether.

  本发明提供了：一种聚合反应速度快、生产效率高的聚环氧烷的生产工艺；一种聚合催化剂及其分散液，它对上述聚环氧烷等聚合物的生产工艺是有效的；以及一种有机金属微粒及其生产工艺，该微粒例如可用作上述聚合催化剂。在其方法中，脂肪族多元醇等材料与有机金属化合物在作为反应场的胶束中发生反应，从而制备出超细粒子，该粒子用作主要包括环醚在内的可离子聚合单体的聚合催化剂。
• Multifunctionalized polyethylene glycol derivative and preparation method therefor
  申请人：XIAMEN SINOPEG BIOTECH CO., LTD.

  公开号：US11324827B2

  公开（公告）日：2022-05-10

  Disclosed are a multifunctionalized polyethylene glycol derivative and a preparation method therefor. The derivative has an H-shaped structure as represented by formula (1) and comprises one linear core LPEG and four PEG branch chains, where n1, n2, n3, and n4 respectively are the degrees of polymerization of the branch chains, U1 and U2 are trivalent branching groups connecting the core LPEG to two of the PEG branch chains, F1 and F2 contain a functional group or a protected form R01 thereof and may or may not contain a branched group G, correspondingly, the number of R01 is one or more, F1 and F2 are either identical or different, any one linking group in the molecule or any linking group formed with an adjacent heteroatom group can either remain stable or be degraded, and any one PEG segment in the molecule is discretely polydispersed or monodispersed. The multifunctional polyethylene glycol is flexible and diverse in terms of branch structures and the lengths of branching arms, has various parameters and performance indicators that are adjustable and easy to control, and has a broad applicability.

  本发明公开了一种多功能聚乙二醇衍生物及其制备方法。该衍生物具有由式（1）表示的 H 型结构，包括一个线性核心 LPEG 和四个 PEG 支链，其中 n1、n2、n3 和 n4 分别为支链的聚合度，U1 和 U2 为连接核心 LPEG 和两个 PEG 支链的三价支化基团、F1 和 F2 含有一个官能团或其保护形式 R01，可以含有或不含有支链基团 G，相应地，R01 的数目为一个或多个，F1 和 F2 要么相同要么不同，分子中的任何一个连接基团或与相邻杂原子基团形成的任何连接基团要么保持稳定，要么降解，分子中的任何一个 PEG 段离散多分散或单分散。多功能聚乙二醇的支链结构和支臂长度灵活多样，各种参数和性能指标可调且易于控制，具有广泛的适用性。
• JP1013022A
  申请人：——

  公开号：JP1013022A

  公开（公告）日：1989-01-17
• JPS6413022A
  申请人：——

  公开号：JPS6413022A

  公开（公告）日：1989-01-17