Cu
<sup>II</sup>
‐Catalyzed Asymmetric Hydrosilylation of Diaryl‐ and Aryl Heteroaryl Ketones: Application in the Enantioselective Synthesis of Orphenadrine and Neobenodine
作者:Yao‐Zong Sui、Xi‐Chang Zhang、Jun‐Wen Wu、Shijun Li、Ji‐Ning Zhou、Min Li、Wenjun Fang、Albert S. C. Chan、Jing Wu
DOI:10.1002/chem.201200379
日期:2012.6.11
With certain amounts of sodium tert‐butoxide and tert‐butanol as additives, catalytic amounts of an inexpensive and easy‐to‐handle copper source Cu(OAc)2⋅H2O, a commercially available and air‐stable non‐racemic dipyridylphosphine ligand, as well as the stoichiometric desirable hydride donor polymethylhydrosiloxane (PMHS), formed a versatile in situ catalyst system for the enantioselective reduction
作者:Corrie, Tom J. A.、Ball, Liam T.、Russell, Christopher A.、Lloyd-Jones, Guy C.
DOI:10.1021/jacv6b10018
日期:——
Au-Catalyzed Biaryl Coupling To Generate 5- to 9-Membered Rings: Turnover-Limiting Reductive Elimination versus π-Complexation
作者:Tom J. A. Corrie、Liam T. Ball、Christopher A. Russell、Guy C. Lloyd-Jones
DOI:10.1021/jacs.6b10018
日期:2017.1.11
The intramolecular gold-catalyzed arylation of arenes by aryl-trimethylsilanes has been investigated from both mechanistic and preparative aspects. The reaction generates 5- to 9-membered rings, and of the 44 examples studied, 10 include a heteroatom (N, O). Tethering of the arene to the arylsilane provides not only a tool to probe the impact of the conformational flexibility of Ar-Au-Ar intermediates