7-oxo-7H-benz[de]anthracene-9-sulfonic acid | 56073-25-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 7-oxo-7H-benz[de]anthracene-9-sulfonic acid
• 英文别名: 7-Oxo-7H-benz[de]anthracen-9-sulfonsaeure；Benzanthion；Benzanthrone-9-sulfonic acid；7-oxobenzo[a]phenalene-9-sulfonic acid
• CAS: 56073-25-7
• 化学式: C₁₇H₁₀O₄S
• 分子量: 310.33
• InChiKey: MEUVHCCOUZQMQS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  79.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  硫酸 、 7-oxo-7H-benz[de]anthracene-9-sulfonic acid 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Examen de la preuve dans la documentation sur l’anesthésie: enquête et évaluation des articles sur les céphalées obstétricales post-ponction durale

  摘要：

  Purpose: To describe a bibliographic database on the literature of postdural puncture headache (PDPH) in the obstetrical population, to describe the research architecture in this field, and to evaluate the quality of case-control studies, cohort studies, and controlled clinical trials on PDPH.Methods: Computerized bibliographic searches, citation review, and hand searches were conducted to find all relevant citations on incidence, clinical course, prevention, or treatment of PDPH in parturients. The study design and topic(s) covered by each study were evaluated. Case-control studies and cohort studies were evaluated using the Quality Index; clinical trials were evaluated using the Jadad scale.Results: One hundred ninety-six relevant citations were published between 1949 and 1999. Research on PDPH has been increasing rapidly with the majority of studies published in the 1990's. Incidence and prevention were the focus of over half of all citations. Optimal study designs were infrequently utilized. The methodological quality was poor for observational studies (Quality Index 10/29) and clinical trials (Jadad scale 2/5).Conclusion: Although the amount of research on PDPH in parturients is increasing, use of optimal study designs and improvement in methodology is needed.

  DOI：

  10.1007/bf03020418
• 作为产物：
  描述：

  苯并蒽酮 在 硫酸 作用下， 生成 7-oxo-7H-benz[de]anthracene-9-sulfonic acid 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Lauer; Hirata, Journal fur praktische Chemie (Leipzig 1954), 1936, vol. <2> 145, p. 287,289

  摘要：

  DOI：

文献信息

• Ioffe; Pawlowa, Zhurnal Obshchei Khimii, 1944, vol. 14, p. 144,146, 147
  作者：Ioffe、Pawlowa

  DOI：——

  日期：——
• Ioffe; Mel'tewa, Zhurnal Obshchei Khimii, 1939, vol. 9, p. 1104,1105,1107
  作者：Ioffe、Mel'tewa

  DOI：——

  日期：——
• Examen de la preuve dans la documentation sur l’anesthésie: enquête et évaluation des articles sur les céphalées obstétricales post-ponction durale
  作者：Peter T. -L. Choi、Saramin E. Galinski、Stefan Lucas、Lawrence Takeuchi、Alejandro R. Jadad

  DOI：10.1007/bf03020418

  日期：2002.1

  Purpose: To describe a bibliographic database on the literature of postdural puncture headache (PDPH) in the obstetrical population, to describe the research architecture in this field, and to evaluate the quality of case-control studies, cohort studies, and controlled clinical trials on PDPH.Methods: Computerized bibliographic searches, citation review, and hand searches were conducted to find all relevant citations on incidence, clinical course, prevention, or treatment of PDPH in parturients. The study design and topic(s) covered by each study were evaluated. Case-control studies and cohort studies were evaluated using the Quality Index; clinical trials were evaluated using the Jadad scale.Results: One hundred ninety-six relevant citations were published between 1949 and 1999. Research on PDPH has been increasing rapidly with the majority of studies published in the 1990's. Incidence and prevention were the focus of over half of all citations. Optimal study designs were infrequently utilized. The methodological quality was poor for observational studies (Quality Index 10/29) and clinical trials (Jadad scale 2/5).Conclusion: Although the amount of research on PDPH in parturients is increasing, use of optimal study designs and improvement in methodology is needed.
• Lauer; Hirata, Journal fur praktische Chemie (Leipzig 1954), 1936, vol. <2> 145, p. 287,289
  作者：Lauer、Hirata

  DOI：——

  日期：——