2-(methyl 2'-chloropropionato)ethyl acrylate | 403790-82-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-(methyl 2'-chloropropionato)ethyl acrylate
• 英文别名: 2-(2'-chloropropionyloxy)ethyl acrylate；2-(2-chloropropionyloxy)ethyl acrylate；2-Prop-2-enoyloxyethyl 2-chloropropanoate
• CAS: 403790-82-9
• 化学式: C₈H₁₁ClO₄
• 分子量: 206.626
• InChiKey: YYMAYXYORMNPIR-UHFFFAOYSA-N

物化性质

• 沸点：
  277.9±20.0 °C(Predicted)
• 密度：
  1.184±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-(4-氯-2-氟-5-巯基苯基)-1-甲基-6-(三氟甲基)嘧啶-2,4(1H,3H)-二酮 、 2-(methyl 2'-chloropropionato)ethyl acrylate 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 反应 2.0h， 以88%的产率得到2-((2-((2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2H)-yl)phenyl)thio)propanoyl)oxy)ethyl acrylate
  参考文献：
  名称：

  丙烯酸酯和丙烯酰胺取代嘧啶二酮作为潜在 PPO 除草剂的设计和合成

  摘要：

  PPO 除草剂因其环保特性而广泛应用于农业领域，并成为许多科学家的研究重点。取而代之的是，本研究将丙烯酸酯和丙烯酰胺取代的嘧啶二酮作为 PPO 除草剂候选物。大多数合成的化合物对单子叶植物和双子叶植物杂草都表现出除草活性，尤其是化合物5a，它对商品化的苯嘧磺草胺表现出非选择性的优越活性。进一步测试了化合物5a的残留效果，并显示出有希望的结果，因为种植下一批作物需要更短的时间。合成的丙烯酸酯和丙烯酰胺取代的嘧啶二酮，尤其是5a 通过进一步的测试和研究，可以潜在地用于开发商业原卟啉原氧化酶抑制剂。

  DOI：

  10.1016/j.bmc.2020.115959
• 作为产物：
  描述：

  2-氯丙酰氯 、 丙烯酸羟乙酯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 2-(methyl 2'-chloropropionato)ethyl acrylate
  参考文献：
  名称：

  原子转移自由基聚合在乳液中合成超支化聚丙烯酸酯

  摘要：

  DOI：

  10.1021/ma011467c

文献信息

• Shaving article with surface modification
  申请人：The Gillette Company LLC

  公开号：US10751896B2

  公开（公告）日：2020-08-25

  A method of making a shaving article comprising a substrate comprising stainless steel; and an external polymer coating comprising polymer brushes, the method comprising the steps of: providing said substrate; providing a initiating species comprising an anchor group that is chemically reactive with surface moieties on the substrate, and a polymerization initiator group; reacting said anchor group with said surface moieties of the substrate; providing monomers reactive for polymerization with the polymerization initiator; and polymerizing the monomers with the initiator group of the initiating species.

  一种制造剃须用品的方法，包括由不锈钢组成的基材；以及由聚合物刷组成的外部聚合物涂层，该方法包括以下步骤：提供所述基材；提供由与基材表面分子具有化学反应性的锚基团和聚合引发剂基团组成的引发剂；使所述锚基团与基材的所述表面分子反应；提供与聚合引发剂具有聚合反应性的单体；以及使单体与引发剂的引发剂基团聚合。
• Synthesis and Characterization of Polymer Brushes of Poly(<i>N</i>,<i>N</i>-dimethylacrylamide) from Polystyrene Latex by Aqueous Atom Transfer Radical Polymerization
  作者：K. N. Jayachandran、Aniko Takacs-Cox、Donald E. Brooks

  DOI：10.1021/ma011651y

  日期：2002.5.21

  Negatively charged polystyrene latex was synthesized, and a copolymer shell of 2-(methyl-2'-chloropropionato)ethyl acrylate (HEA-Cl) and styrene was added, from which poly(N,N-dimethylacrylamide) (PDMA) was polymerized by atom transfer radical polymerization in aqueous suspension at room temperature. Increasing monomer concentration in the presence of CuCl or CuBr and one of three ligands (N,N,N',N',N"-pentamethyldiethylenetriamine (PMDETA), 1,1,4,7,10,10-hexamethyltriethylenetetramine (HMTETA), and tris [2-(dimethylamino)ethyl] amine (Me6TREN)) produced grafts whose molecular weight increased to over 600 000 and polydispersities in the range of 1.3-1.8, determined from chains recovered following cleavage by base. Hydrodynamic brush thicknesses were 70-800 nm, and average chain separations, calculated from M-n and the mass of polymer recovered per particle, varied from 4.0 to 1.1 nm. Very high grafting densities were achieved with good molecular weight control, the highest densities yet reported for high molecular weight polymer chains grown from a surface. Control of the polymerization was improved by addition of Cu(II) to enhance deactivation of free radicals, by including a low concentration of exogenous hydrophobic initiator at high monomer concentration and by reducing latex concentration. Increasing the concentration of exogenous initiator reduced graft thickness but eliminated control over the polydispersity. The unusual conditions required for optimization of the reaction and the observation of decreasing chain separation as M-n increased were explained by invoking a model of the particle surface that took into account the finite depth and high copolymer concentration of the region in which chains were initiated and particularly the fixed charges due to the sulfate initiator of shell copolymerization.
• Polymer Coating of Steel by a Combination of Electrografting and Atom-Transfer Radical Polymerization
  作者：M. Claes、S. Voccia、C. Detrembleur、C. Jérôme、B. Gilbert、Ph. Leclère、V. M. Geskin、R. Gouttebaron、M. Hecq、R. Lazzaroni、R. Jérôme

  DOI：10.1021/ma0217130

  日期：2003.8.1

  Cathodic electrografting of poly(2-chloropropionate ethyl acrylate) (poly[cPEA]) onto steel followed by the styrene grafting-from by atom transfer radical polymerization (ATRP) is an efficient strategy to impart strong adhesion to polystyrene films onto the electrically conductive substrate. Electrografting of poly(cPEA) chains at an appropriate potential and persistence of the activated chloride in the grafted chains were confirmed by XPS. Polystyrene deposition by ATRP with a ruthenium-based catalyst was analyzed by scanning electron microscopy and Raman spectroscopy. Adhesion of the polystyrene layer to the substrate is so strong that it cannot be detached by standard Scotch brand tapes. Moreover, local thermal analysis showed a loss of mobility for the PS chains tethered at the surface.
• ELECTRICALLY CONDUCTIVE FILMS FORMED FROM DISPERSIONS COMPRISING CONDUCTIVE POLYMERS AND HYPERBRANCHED POLYMERS
  申请人：Air Products and Chemicals, Inc.

  公开号：EP2438120A1

  公开（公告）日：2012-04-11
• Electrically Conductive Films Formed From Dispersions Comprising Conductive Polymers and Hyperbranched Polymers
  申请人：Zheng Shiying

  公开号：US20100308281A1

  公开（公告）日：2010-12-09

  An aqueous dispersion and a method for making an aqueous dispersion. The dispersion including at least one conductive polymer, such as a polythienothiophene, at least one hyperbranched polymer and optionally at least one colloid-forming polymeric acid and one non-fluorinated polymeric acid. Devices utilizing layers formed of the aqueous dispersions are also disclosed.