N-benzyl-2-phenylethanimidamide | 69981-47-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-benzyl-2-phenylethanimidamide
• 英文别名: N-benzyl-2-phenylacetimidamide；N-benzyl-2-phenyl-acetamidine；N-Benzyl-2-phenyl-acetamidin；C-Phenyl-N-benzyl-acetamidin；N-Benzyl-phenacetamidin；N'-benzyl-2-phenylethanimidamide
• CAS: 69981-47-1
• 化学式: C₁₅H₁₆N₂
• mdl: MFCD20535708
• 分子量: 224.305
• InChiKey: XRPNFHZMXJLYKS-UHFFFAOYSA-N

物化性质

• 沸点：
  360.0±45.0 °C(Predicted)
• 密度：
  1.02±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.133
• 拓扑面积：
  38.4
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-benzyl-2-phenylethanimidamide 在 sodium hydroxide 作用下， 生成 N-苄基苯乙酰胺
  参考文献：
  名称：

  Sugasawa; Ohara, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1952, vol. 72, p. 1036

  摘要：

  DOI：
• 作为产物：
  描述：

  苯乙腈 、 苄胺 在 aluminum (III) chloride 作用下， 反应 0.83h， 以54%的产率得到N-benzyl-2-phenylethanimidamide
  参考文献：
  名称：

  通过串联氧化重排和异氰酸酯消除反应，由N取代的Am合成仲酰胺

  摘要：

  在这项工作中，已经描述了将N-取代的idine转化为仲酰胺的有效串联过程。该过程涉及Ñ通过与双衬底的反应-acylurea形成（酰氧基）（苯基）-λ 3 -iodane随后的异氰酸酯的消除。通过与羧酸的配体交换从可商购的二乙酸苯基碘（III）苯乙酸[PhI（OAc）2（PIDA）]获得高碘烷试剂。该ñ预取代的idine底物很容易从容易获得的腈中合成。该方法适用于基于脂族和（杂）芳族胺的仲酰胺合成，包括由位阻酸和胺组成的挑战性酰胺。而且，该方案允许将目标酰胺（基于苯胺）中的空间体积与电子缺乏结合起来。基于涉及羧酸和胺的经典缩合反应，这样的化合物难以有效地合成。总体而言，在脂肪族和（杂）芳族体系中，合成方案都能将腈转化为仲酰胺。

  DOI：

  10.1002/adsc.201400648

文献信息

• Sulfated tungstate catalyzed activation of nitriles: addition of amines to nitriles for synthesis of amidines
  作者：Sachin D. Veer、Kamlesh V. Katkar、Krishnacharya G. Akamanchi

  DOI：10.1016/j.tetlet.2016.07.073

  日期：2016.9

  the synthesis of amidines by direct nucleophilic addition of amines to nitriles using sulfated tungstate as heterogeneous catalyst is described. Highlight of the method is its applicability for the synthesis of amidines using a wide variety of amines including ammonia as ammonium acetate and nitriles. Catalyst is mildly acidic, stable, easy to prepare and separate from the reaction mass.

  描述了通过使用硫酸钨作为非均相催化剂将胺直接亲核加成到腈中的一种高效温和的method合成方法。该方法的重点是其适用于使用多种胺（包括氨，乙酸铵和腈）合成am。催化剂呈弱酸性，稳定，易于制备并与反应物料分离。
• Effect of theory-based feature correlations on typicality judgments
  作者：Woo-Kyoung Ahn、Jessecae K. Marsh、Christian C. Luhmann、Kevin Lee

  DOI：10.3758/bf03195270

  日期：2002.1

  In the present study, we examine what types of feature correlations are salient in our conceptual representations. It was hypothesized that of all possible feature pairs, those that are explicitly recognized as correlated (i.e., explicit pairs) and affect typicality judgments are the ones that are more likely theory based than are those that are not explicitly recognized (i.e., implicit pairs). Real-world categories and their properties, taken from Malt and Smith (1984), were examined. We found that explicit pairs had a greater number of asymmetric dependency relations (i.e., one feature depends on the other feature, but not vice versa) and stronger dependency relations than did implicit pairs, which were statistically correlated in the environment but were not recognized as such. In addition, people more often provided specific relation labels for explicit pairs than for implicit pairs; these labels were most often causal relations. Finally, typicality judgments were more affected when explicit correlations were broken than when implicit correlations were broken. It is concluded that in natural categories, feature correlations that are explicitly represented and affect typicality judgments are the ones about which people have theories.
• Reynaud,P. et al., Bulletin de la Societe Chimique de France, 1978, vol. <II>, p. 449 - 456
  作者：Reynaud,P. et al.

  DOI：——

  日期：——
• NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT
  申请人：UNIVERSITY OF DAYTON

  公开号：EP1472319A1

  公开（公告）日：2004-11-03
• [EN] NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT<br/>[FR] PIGMENTS ANTICORROSION NON TOXIQUES A BASE DE COBALT
  申请人：UNIV DAYTON

  公开号：WO2003060019A1

  公开（公告）日：2003-07-24

  Corrosion-inhibiting pigments based on cobalt are described that contain a trivalent or tetravalent cobalt/valence stabilizer complex. An inorganic or organic material is used to stabilize the trivalent or tetravalent cobalt ion to form a compound that is sparingly soluble in water. Specific stabilizers are chosen to control the release rate of trivalent or tetravalent cobalt during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Cobalt/valence stabilizer combinations are chosen based on the well-founded principles of cobalt coordination chemistry. Many cobalt-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium systems.