1,4-bis(ethylthio)-2,3,5,6-tetrafluorobenzene | 36639-07-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 1,4-bis(ethylthio)-2,3,5,6-tetrafluorobenzene
• 英文别名: 1,4-Bis(ethylsulfanyl)-2,3,5,6-tetrafluorobenzene；1,4-bis(ethylsulfanyl)-2,3,5,6-tetrafluorobenzene
• CAS: 36639-07-3
• 化学式: C₁₀H₁₀F₄S₂
• 分子量: 270.315
• InChiKey: PCBLJFUXBPRTKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  二乙基二硫醚 、 五氟苯 在 potassium hydroxide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 10.0h， 以90%的产率得到1,4-bis(ethylthio)-2,3,5,6-tetrafluorobenzene
  参考文献：
  名称：

  通过C–H，C–F键激活和C–S键形成，将五氟苯与二硫键硫醇化†

  摘要：

  据报道，五氟苯与二硫化物之间通过CH，CF键活化和CS键形成而发生无金属的硫醇化反应。在温和的条件下，由五氟苯和二硫化物可以中等至良好的产率制备双硫代四氟苯衍生物。给出了反应的可能机理。

  DOI：

  10.1039/c7ob02836a

文献信息

• Synthesis of polyfluoroarylalkyl sulfide compounds
  作者：Wayne E. Ward、Stephen Sicree、Brian Chen、Christ Tamborski

  DOI：10.1016/0022-1139(94)03200-j

  日期：1995.7

  Syntheses of RC6F4SR′ compounds (where R = F, C6F5, H, R′ = alkyl, trifluorovinyl) have been accomplished through reaction between ArfSM (where M = Cu, MgX) and an alkyl or trifluorovinyl halide in dimethylacetamide solvent. Minor by-products from competing reactions have been partially characterized by GC-MS analysis.

  RC 6 F 4 SR'化合物（其中R = F，C 6 F 5，H，R'=烷基，三氟乙烯基）的合成是通过Ar f SM（其中M = Cu，MgX）和烷基或在二甲基乙酰胺溶剂中的三氟乙烯基卤化物。竞争反应产生的少量副产物已通过GC-MS分析得到部分表征。
• LADDER POLYMERS WITH INSTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF
  申请人：Du Naiying

  公开号：US20110190409A1

  公开（公告）日：2011-08-04

  A polymer of formula (I): where: n is an integer from 10 to 5,000; m is an integer from 10 to 5,000; Ar1 and Ar3 are the same or different and are residues derived from a tetra-hydroxy aromatic monomer, the tetra-hydroxy aromatic monomer being wherein R is the same or different and is H or a C 1 -C 8 alkyl, C2-C8 alkenyl or C 3 -C 8 cycloalkyl group; and, Ar2 and Ar4 are the same or different and are residues derived from a tetra-halogenated aromatic monomer, the tetra-halogenated aromatic monomer being wherein X is F, Cl or Br, and R1 and R2 are the same or different and are wherein y is an integer from 1 to 8; with the proviso that when Ar1 is the same as Ar3 and Ar2 is the same as Ar4, R1 and R2 are not both —CN is useful as a material for gas separation, vapor separation, adsorbents or catalysis.
• Modification of Peptides via SNAr Reactions of Thiols with Fluorinated Aromatics
  申请人：Pentelute Bradley L.

  公开号：US20140113871A1

  公开（公告）日：2014-04-24

  Disclosed are compounds and methods relating to a chemical transformation for the conjugation of unprotected peptide biomolecules via a S N Ar process between highly fluorinated aryl moieties and thiols (“fluoroaryl-thiol-click”).
• LADDER POLYMERS WITH INTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF
  申请人：DU Naiying

  公开号：US20140243441A1

  公开（公告）日：2014-08-28

  A polymer of formula (I): where: n is an integer from 10 to 5,000; m is an integer from 10 to 5,000; Ar1 and Ar3 are the same or different and are residues derived from a tetra-hydroxy aromatic monomer, the tetra-hydroxy aromatic monomer being wherein R is the same or different and is H or a C 1 -C 8 alkyl, C 2 -C 8 alkenyl or C 3 -C 8 cycloalkyl group; and, Ar2 and Ar4 are the same or different and are residues derived from a tetra-halogenated aromatic monomer, the tetra-halogenated aromatic monomer being wherein X is F, Cl or Br, and R1 and R2 are the same or different and are wherein y is an integer from 1 to 8; with the proviso that when Ar1 is the same as Ar3 and Ar2 is the same as Ar4, R1 and R2 are not both —CN is useful as a material for gas separation, vapor separation, adsorbents or catalysis.
• US9018172B2
  申请人：——

  公开号：US9018172B2

  公开（公告）日：2015-04-28