N,N'-dimethyl-N,N'-bis(4-vinylphenyl)-3-oxapentanediamide | 136821-00-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-dimethyl-N,N'-bis(4-vinylphenyl)-3-oxapentanediamide
• 英文别名: 2-[2-(4-ethenyl-N-methylanilino)-2-oxoethoxy]-N-(4-ethenylphenyl)-N-methylacetamide
• CAS: 136821-00-6
• 化学式: C₂₂H₂₄N₂O₃
• 分子量: 364.444
• InChiKey: GWSSDALPCYDHQD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  49.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N,N'-bis-(4-vinylphenyl)-3-oxapentanediamide 、 碘甲烷 在 二环己烷并-18-冠醚-6 、 potassium tert-butylate 作用下， 以 四氢呋喃 为溶剂， 反应 24.0h， 以51.3%的产率得到N,N'-dimethyl-N,N'-bis(4-vinylphenyl)-3-oxapentanediamide
  参考文献：
  名称：

  Rosatzin, Thomas; Andersson, Lars I.; Simon, Wilhelm, Journal of the Chemical Society. Perkin transactions II, 1991, # 8, p. 1261 - 1266

  摘要：

  DOI：

文献信息

• Ion-detecting sensors comprising plasticizer-free copolymers
  申请人：Auburn University

  公开号：US20030213691A1

  公开（公告）日：2003-11-20

  Ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of said ion, wherein at least a portion of the functionalized ionophore is grafted into the copolymer through covalent linkages. Sensors may comprise ionophores such as hydrophilic crown ethers or functionalized derivative of 3-oxapentandiaminde-type ionophores. This invention further provides sensors for detecting target ions in a sample, comprising plasticizer-free molecularly imprinted polymers, wherein the polymers comprise polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of said ion. In particular, a magnesium ion sensor comprising a functionalized derivative of a 3-oxapentandiaminde-type calcium ion-selective ionophore is provided. Sensors of this invention include carrier-based ion-selective electrodes or optodes such as thin film ion-specific optodes, particle-based optodes, or bulk optodes.

  提供了用于检测样品中目标离子的离子检测传感器。传感器包括无增塑剂共聚物，该共聚物由具有不同长度的下垂烷基的甲基丙烯酸酯单体的聚合单元和所述离子的官能化离子团组成，其中至少一部分官能化离子团通过共价键接枝到共聚物中。传感器可包括亲水性冠醚或 3-氧代戊二茚型离子团的官能化衍生物等离子团。本发明进一步提供了用于检测样品中目标离子的传感器，该传感器由不含增塑剂的分子印迹聚合物组成，其中聚合物由具有不同长度的下垂烷基的甲基丙烯酸酯单体的聚合单元和所述离子的官能化离子团组成。本发明特别提供了一种镁离子传感器，该传感器由 3-氧杂戊二胺型钙离子选择性离子团的官能化衍生物组成。本发明的传感器包括基于载体的离子选择电极或光电极，如薄膜离子特异性光电极、基于颗粒的光电极或块状光电极。
• Imprinting a substrate for separation of a target molecule from a fluid medium
  申请人：Belfort J. Georges

  公开号：US20070128423A1

  公开（公告）日：2007-06-07

  The present invention is directed to a method of producing a substrate suitable for separation of a target molecule from a fluid medium. This method includes providing an emulsion comprising a water phase in an oil phase, where the oil phase contains a polymerizable monomer and the water phase contains the target molecule. The substrate, having pores extending from one side of the substrate to another side of the substrate, is coated with the emulsion, and the monomer in the emulsion coated substrate is then polymerized. The water and target molecule are removed from the polymerized, emulsion coated substrate. As a result, the substrate is imprinted with the target molecule and, therefore, is suitable for separation of the target molecule from a fluid medium. The resulting article and its use are also disclosed.
• US7201876B2
  申请人：——

  公开号：US7201876B2

  公开（公告）日：2007-04-10
• [EN] ION-DETECTING SENSORS COMPRISING PLASTICIZER-FREE COPOLYMERS<br/>[FR] DETECTEURS D'IONS CONTENANT DES COPOLYMERES EXEMPTS DE PLASTIFIANTS
  申请人：BECKMAN COULTER INC

  公开号：WO2004081522A2

  公开（公告）日：2004-09-23

  Ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of said ion, wherein at least a portion of the functionalized ionophore is grafted into the copolymer through covalent linkages. Sensors may comprise ionophores such as hydrophilic crown ethers of functionalized derivative of 3-oxapentandiaminde-type ionophores. This invention further provides sensors for detecting target ions in a sample, comprising plasticizer-free molecularly imprinted polymers, wherein the polymers comprise polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of said ion. In particular, a magnesium ion sensor comprising a functionalized derivative of a 3-0xapentandiaminde-type calcium ion-selective ionophore is provided. Sensors of this invention include carrier-based ion-selective electrodes or optodes such as thin film ion-specific optodes, particle-based optodes, or bulk optodes.
• Rosatzin, Thomas; Andersson, Lars I.; Simon, Wilhelm, Journal of the Chemical Society. Perkin transactions II, 1991, # 8, p. 1261 - 1266
  作者：Rosatzin, Thomas、Andersson, Lars I.、Simon, Wilhelm、Mosbach, Klaus

  DOI：——

  日期：——