α-Ethyl-α-methyl-glutarsaeure | 7769-82-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: α-Ethyl-α-methyl-glutarsaeure
• 英文别名: Methyl-ethyl-glutaric acid；2-ethyl-2-methylpentanedioic acid
• CAS: 7769-82-6
• 化学式: C₈H₁₄O₄
• 分子量: 174.197
• InChiKey: AMJKBXSGXSAACI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• STEROID COMPOUND COMBINED WITH POLYSACCHARIDE
  申请人：Eisai Co., Ltd.

  公开号：EP0540751A1

  公开（公告）日：1993-05-12

  A compound which can maintain a blood steroid level unchanged for long after administration, obtained by combining a steroid derivative with a polysaccharide directly or via a spacer. Desirable examples of the steroid derivative include ones having carboxyl and/or hydroxyl groups, and those of the spacer include polybasic carboxylic acids, while those of the polysaccharide include water-soluble ones such as dextran. When administered, the compound releases the steroid in the blood and the steroid level is kept constant for long.

  通过将类固醇衍生物与多糖直接或通过间隔物结合而获得的一种化合物，该化合物可在用药后长期保持血液中类固醇水平不变。类固醇衍生物的理想实例包括具有羧基和/或羟基的类固醇衍生物，多糖的理想实例包括多基羧酸，多糖的理想实例包括水溶性多糖，如葡聚糖。给药时，化合物在血液中释放类固醇，类固醇水平长期保持恒定。
• Flame retardants with high halogen content and low viscosity
  申请人：Albemarle Corporation

  公开号：EP2107079A2

  公开（公告）日：2009-10-07

  A flame retardant formulation which is the combination of at least (1) at least one bromine-containing polyol flame retardant formed from the reaction of (a) tetrabromophthalic anhydride, (b) an aliphatic polyol, and (c) an epoxide, and (2) at least one aliphatic diester of an alkane dicarboxylic acid, with the proviso that the formulation has a viscosity at 25°C of about 20,000 cps or less, and a bromine content of at least about 40 wt%. A flame retardant compound formed from A) tetrabromophthalic anhydride; B) diethylene glycol; C) at least one alpha-omega alkane diol, or at least one alpha-omega alkane diol and at least one aliphatic monool; and D) at least one alkylene oxide; with the proviso that the compound has a viscosity at 25°C of about 60,000 cps or less, and a bromine content of at least about 43 wt%. Polymer compositions formed from (a) a polyurethane or a polyisocyanurate and (b) a formulation of the invention. One process to make a formulation involves heating a mixture of (a), (b), and at least one liquid aliphatic diester of a alkane dicarboxylic acid to form an intermediate composition; and then the intermediate is contacted one or more times with (c) thereby producing the formulation. Optionally, excess (c) is removed.

  一种阻燃剂配方，它至少是以下物质的组合：(1)至少一种含溴多元醇阻燃剂，由(a)四溴邻苯二甲酸酐、(b)脂肪族多元醇和(c)环氧化物反应生成；(2)至少一种烷烃二羧酸脂肪族二酯，但该配方在 25°C 时的粘度约为 20°C、(2) 烷烃二羧酸的至少一种脂肪族二酯，但该制剂在 25°C 时的粘度不超过约 20,000 cps，溴含量不低于约 40 wt%。由以下物质形成的阻燃化合物：A) 四溴邻苯二甲酸酐；B) 二甘醇；C) 至少一种α-ω-烷二醇，或至少一种α-ω-烷二醇和至少一种脂族一元醇；以及 D) 至少一种环氧亚烷烃；但条件是该化合物在 25°C 时的粘度约为 60,000 cps 或更低，溴含量至少约为 43 wt%。由(a)聚氨酯或聚异氰脲酸酯和(b)本发明配方形成的聚合物组合物。制备配方的一种工艺包括加热(a)、(b)和至少一种烷烃二羧酸的液态脂肪族二酯类的混合物，以形成中间体组合物；然后将中间体与(c)接触一次或多次，从而制得配方。可选择去除多余的 (c)。
• Composition comprising a layered double hydroxide
  申请人：Akzo Nobel N.V.

  公开号：EP2174909A1

  公开（公告）日：2010-04-14

  Composition comprising (i) a layered double hydroxide containing charge-balancing anions and (ii) one or more organic compounds that are capable of adsorbing to and/or reacting with an inorganic alkaline surface, wherein at least part of said organic compound(s) does not serve as said charge-balancing anions. The presence of said organic compound reduces or even prevents discoloration of LDH-containing polymeric matrices.

  包含以下成分的组合物：(i) 含有电荷平衡阴离子的层状双氢氧化物；(ii) 一种或多种能够吸附到无机碱性表面并/或与之发生反应的有机化合物，其中至少一部分所述有机化合物不作为所述电荷平衡阴离子。 所述有机化合物的存在可减少甚至防止含 LDH 聚合物基质的褪色。
• Compositions and method for breaking hydraulic fracturing fluids
  申请人：Clearwater International LLC

  公开号：EP2374861A1

  公开（公告）日：2011-10-12

  Breaking compositions are disclosed for controlled breaking of borate cross-linked fracturing fluids, and to method for making and using same, where the composition includes an oxidative component and an ester component.

  本发明公开了用于控制硼酸盐交联压裂液裂解的裂解组合物及其制造和使用方法，其中组合物包括氧化组分和酯组分。
• PHOSPHOLIPID DERIVATIVE AND PH-RESPONSIVE LIPOSOMES
  申请人：NOF Corporation

  公开号：EP2500348A1

  公开（公告）日：2012-09-19

  A phospholipid derivative represented by the following formula (1) wherein each symbol is as described in the specification; a liposome containing the phospholipid derivative, and the like.

  下式（1）所代表的磷脂衍生物 其中各符号如说明书所述；含有该磷脂衍生物的脂质体等。