(Z)-[(pent-2-enyloxy)methyl]benzene | 107692-01-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (Z)-[(pent-2-enyloxy)methyl]benzene
• 英文别名: (Z)-2-pentenyl benzyl ether；[(Z)-pent-2-enoxy]methylbenzene
• CAS: 107692-01-3
• 化学式: C₁₂H₁₆O
• 分子量: 176.258
• InChiKey: DTFRQORTTWXRCO-CLTKARDFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (Z)-[(pent-2-enyloxy)methyl]benzene 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以90%的产率得到
  参考文献：
  名称：

  环氧化物的钴催化三氟甲氧基化

  摘要：

  已经基于使用钴催化剂开发了通过三氟甲基芳基磺酸盐的亲核三氟甲氧基化反应的环氧化物的催化开环反应。该反应为在温和条件下直接构建范围广泛的邻位三氟甲氧基醇提供了一种有效、简单的途径。此外，该方法可以将末端环氧化物转化为具有良好化学和区域选择性的目标产物。

  DOI：

  10.1021/jacs.8b10298
• 作为产物：
  描述：

  顺-4-苄氧基-2-丁烯-1-醇 在 甲基磺酰氯 、 lithium chloride 作用下， 以 乙醚 、 N,N-二甲基甲酰胺 为溶剂， 反应 7.0h， 生成 (Z)-[(pent-2-enyloxy)methyl]benzene
  参考文献：
  名称：

  Yadav, J. S.; Reddy, P. Satyanarayana, Synthetic Communications, 1986, vol. 16, # 9, p. 1119 - 1132

  摘要：

  DOI：

文献信息

• PROCESS FOR THE SYNTHESIS OF KETONES FROM INTERNAL ALKENES
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US20140194604A1

  公开（公告）日：2014-07-10

  The present invention is directed to methods for oxidizing internal olefins to ketones. In various embodiments, each method comprising contacting an organic substrate, having an initial internal olefin, with a mixture of (a) a biscationic palladium salt; and (b) an oxidizing agent; dissolved or dispersed in a solvent system to form a reaction mixture, said solvent system comprising at least one C 2-6 carbon nitrile and optionally at least one secondary alkyl amide, said method conducted under conditions sufficient to convert at least 50 mol % of the initial internal olefin to a ketone, said ketone positioned on a carbon of the initial internal olefin. The transformation occurs at room temperature and shows wide substrate scope. Applications to the oxidation of seed oil derivatives and a bioactive natural product are described.

  本发明涉及将内烯烃氧化为酮的方法。在各种实施方式中，每种方法包括将具有初始内烯烃的有机底物与（a）双阳离子钯盐的混合物；和（b）氧化剂接触，溶解或分散在溶剂体系中形成反应混合物，所述溶剂体系包括至少一种C2-6碳腈和可选地至少一种次烷基酰胺，所述方法在足以将初始内烯烃的至少50摩尔％转化为酮的条件下进行，所述酮位于初始内烯烃的碳上。该转化在室温下发生，并显示出广泛的底物范围。描述了将其应用于种子油衍生物和生物活性天然产物的氧化。
• HIGHLY Z-SELECTIVE OLEFINS METATHESIS
  申请人：Schrock Richard R.

  公开号：US20110077421A1

  公开（公告）日：2011-03-31

  The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions.

  本发明通常涉及催化剂和过程，用于通过同型交换反应从末端烯烃中Z-选择性地形成内部烯烃。
• HIGHLY Z-SELECTIVE OLEFIN METATHESIS
  申请人：Massachusetts Institute of Technology

  公开号：US20160008802A1

  公开（公告）日：2016-01-14

  The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions.

  本发明涉及催化剂和过程，用于通过同型交换反应从末端烯烃形成内部烯烃的Z-选择性。
• Titanium-Catalyzed Asymmetric Epoxidation of Non-Activated Olefins with Hydrogen Peroxide
  作者：Yuji Sawada、Kazuhiro Matsumoto、Tsutomu Katsuki

  DOI：10.1002/anie.200700949

  日期：2007.6.11
• CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS
  申请人：California Institute Of Technology

  公开号：US20140288319A1

  公开（公告）日：2014-09-25

  The invention pertains to the use of Group 8 transition metal carbene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand are used to catalyze cross-metathesis reactions to provide a variety of substituted and functionalized olefins, including phosphonate-substituted olefins, directly halogenated olefins, 1,1,2-trisubstituted olefins, and quaternary allylic olefins. The invention further provides a method for creating functional diversity using the aforementioned complexes to catalyze cross-metathesis reactions of a first olefinic reactant, which may or may not be substituted with a functional group, with each of a plurality of different olefinic reactants, which may or may not be substituted with functional groups, to give a plurality of structurally distinct olefinic products. The methodology of the invention is also useful in facilitating the stereoselective synthesis of 1,2-disubstituted olefins in the cis configuration.