Ultrasound assisted, ruthenium-exchanged FAU-Y zeolite catalyzed alkylation of indoles with epoxides under solvent free conditions
作者:Alireza Khorshidi
DOI:10.1016/j.ultsonch.2011.11.003
日期:2012.5
Ruthenium-exchanged FAU-Y zeolite (RuY) was used as a recyclable catalyst for regioselective ring-opening of epoxides with indolesunder irradiation of sonic waves. It was found that a solventfree process, under the above mentioned conditions provides good yields of the desired 3-alkylated indole derivatives.
Ruthenium-catalyzed regioselective ring-opening of aliphatic and aryl epoxides under solvent-free conditions is reported. It was found that RUCl3 center dot nH(2)O catalyzes the Friedel-Crafts alkylation of indoles, providing 3-alkylated derivatives in good yields under mild reaction conditions. (c) 2008 Elsevier Ltd. All rights reserved.
An efficient Friedel–Crafts alkylation of nitrogen heterocycles catalyzed by antimony trichloride/montmorillonite K-10
作者:Yu-Heng Liu、Qiu-Shuang Liu、Zhan-Hui Zhang
DOI:10.1016/j.tetlet.2008.12.022
日期:2009.2
It has been found that SbCl3 supported on montmorillonite K-10 is an efficient and reusable catalyst for Friedel–Crafts alkylation of nitrogenheterocycles such as indoles and pyrroles with epoxides. The reaction gives the corresponding C-alkylated derivatives in good to excellent yields with a high regioselectivity.