2-[4-[(N-Ethyl-N-methylcarbamoyl)methoxy]-3-propoxyphenyl]-2-hydroxyacetic acid propyl ester | 579495-00-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-[4-[(N-Ethyl-N-methylcarbamoyl)methoxy]-3-propoxyphenyl]-2-hydroxyacetic acid propyl ester
• 英文别名: Propyl 2-[4-[2-[ethyl(methyl)amino]-2-oxoethoxy]-3-propoxyphenyl]-2-hydroxyacetate
• CAS: 579495-00-4
• 化学式: C₁₉H₂₉NO₆
• 分子量: 367.442
• InChiKey: KBGKZKNGKFGFRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  26
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  85.3
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-[4-[(N-Ethyl-N-methylcarbamoyl)methoxy]-3-propoxyphenyl]-2-hydroxyacetic acid propyl ester 、 [4-[(N,N-Dipropylcarbamoyl)methoxy]-3-ethoxyphenyl]acetic acid ethyl ester 、 乙酰溴 、 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 在 吡啶 作用下， 生成 2-[4-[(N-ethyl-N-methylcarbamoyl)methoxy]-3-propoxyphenyl]-2-acetoxyacetic acid propyl ester
  参考文献：
  名称：

  Short-acting sedative hypnotic agents for anesthesia and sedation

  摘要：

  这项发明提供了一种用于在哺乳动物中诱导或维持全身麻醉或镇静的化合物组合物和方法。

  公开号：

  US20030153554A1

文献信息

• SHORT-ACTING SEDATIVE HYPNOTIC AGENTS FOR ANESTHESIA AND SEDATION
  申请人：Jenkins Thomas E.

  公开号：US20090253787A1

  公开（公告）日：2009-10-08

  The invention provides compounds compositions and methods useful for inducing or maintaining general anesthesia or sedation in mammals.

  本发明提供了一种化合物、组合物和方法，用于在哺乳动物中诱导或维持全身麻醉或镇静状态。
• Methods for manufacturing silver multilayered films and the articles obtained therefrom
  申请人：——

  公开号：US20040241420A1

  公开（公告）日：2004-12-02

  A silver multilayered film comprises at least one intermediate layer comprising a polymeric resin; a colorant composition and a flake composition, wherein the normal to the individual flakes are oriented at an average angle of about 0 to about 75 degrees with a normal to the multilayered film, and wherein the intermediate layer is located between a first layer and an second layer and further wherein the multilayered film has a lightness greater than or equal to about 60 and a change in lightness as a function of viewing angle of greater than or equal to about 40. A multilayered film comprises an intermediate layer disposed on and in intimate contact with a surface of a first layer and a second layer disposed on and intimate contact with a surface of the intermediate layer opposite the first layer, wherein the intermediate layer comprises a polymeric resin; a colorant composition and a flake composition, wherein the normal to the individual flakes are oriented at an average angle of about 0 to about 75 degrees with a normal to the multilayered film, and further wherein the multilayered film has a lightness greater than or equal to about 60 and a change of lightness as a function of viewing angle of greater than or equal to about 40.
• US6916528B2
  申请人：——

  公开号：US6916528B2

  公开（公告）日：2005-07-12
• US6887866B2
  申请人：——

  公开号：US6887866B2

  公开（公告）日：2005-05-03
• US7015346B2
  申请人：——

  公开号：US7015346B2

  公开（公告）日：2006-03-21