2,2-dimethyl-5-methylimino-1,3-dioxane-4,6-dione N-oxide | 205595-13-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,2-dimethyl-5-methylimino-1,3-dioxane-4,6-dione N-oxide
• 英文别名: N,2,2-trimethyl-4,6-dioxo-1,3-dioxan-5-imine oxide
• CAS: 205595-13-7
• 化学式: C₇H₉NO₅
• 分子量: 187.152
• InChiKey: RDCQUECBYUVQTF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  81.4
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,2-dimethyl-5-methylimino-1,3-dioxane-4,6-dione N-oxide 以 乙腈 为溶剂， 反应 52.0h， 以85%的产率得到2,2,7-trimethyl-4,8-dioxo-7-aza-1,3,6-trioxaspiro[5.4]octane
  参考文献：
  名称：

  Methylation of 5-Isonitroso-1,3-dioxine- 4,6-diones with Diazomethane and Some Reactions of Its Products

  摘要：

  Methylation of 5-isonitroso-1,3-dioxine-4,6-diones (1) with diazomethane afforded 5-methoxyimino-1,3-dioxine-4,6-diones (4) and 5-methylimino-1,3-dioxine-4,6-dione N-oxides (5) together with a cyclic nitrone (7) as a minor product. Compound (5) reacted with two molar equivalents of triphenylphosphine to give phosphonium betaines (8) whereas photoreaction of 5 formed novel spiro compounds (9)via oxaziridine intermediates (G).

  DOI：

  10.3987/com-97-s(n)42
• 作为产物：
  描述：

  重氮甲烷 、 isonitroso Meldrum’s acid 以 乙醚 为溶剂， 反应 0.5h， 以41%的产率得到2,2-dimethyl-5-methylimino-1,3-dioxane-4,6-dione N-oxide
  参考文献：
  名称：

  Methylation of 5-Isonitroso-1,3-dioxine- 4,6-diones with Diazomethane and Some Reactions of Its Products

  摘要：

  Methylation of 5-isonitroso-1,3-dioxine-4,6-diones (1) with diazomethane afforded 5-methoxyimino-1,3-dioxine-4,6-diones (4) and 5-methylimino-1,3-dioxine-4,6-dione N-oxides (5) together with a cyclic nitrone (7) as a minor product. Compound (5) reacted with two molar equivalents of triphenylphosphine to give phosphonium betaines (8) whereas photoreaction of 5 formed novel spiro compounds (9)via oxaziridine intermediates (G).

  DOI：

  10.3987/com-97-s(n)42

文献信息

• Methylation of 5-Isonitroso-1,3-dioxine- 4,6-diones with Diazomethane and Some Reactions of Its Products
  作者：Nobuya Katagiri、Yoshihiro Morishita、Chikara Kaneko

  DOI：10.3987/com-97-s(n)42

  日期：——

  Methylation of 5-isonitroso-1,3-dioxine-4,6-diones (1) with diazomethane afforded 5-methoxyimino-1,3-dioxine-4,6-diones (4) and 5-methylimino-1,3-dioxine-4,6-dione N-oxides (5) together with a cyclic nitrone (7) as a minor product. Compound (5) reacted with two molar equivalents of triphenylphosphine to give phosphonium betaines (8) whereas photoreaction of 5 formed novel spiro compounds (9)via oxaziridine intermediates (G).