2-benzoylpyridine 2,4-dinitrophenylhydrazone | 2910-38-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-benzoylpyridine 2,4-dinitrophenylhydrazone
• 英文别名: 2,4-dinitro-N-[[phenyl(pyridin-2-yl)methylidene]amino]aniline
• CAS: 2910-38-5
• 化学式: C₁₈H₁₃N₅O₄
• 分子量: 363.332
• InChiKey: GQXVHYXSQRJUDJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  129
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂ 、 2-benzoylpyridine 2,4-dinitrophenylhydrazone 以 甲醇 为溶剂， 反应 8.0h， 以81%的产率得到
  参考文献：
  名称：

  Antimicrobial selectivity of ruthenium, rhodium, and iridium half sandwich complexes containing phenyl hydrazone Schiff base ligands towards B. thuringiensis and P. aeruginosa bacteria

  摘要：

  A series of new hydrazone mononuclear complexes of the type [(arene)MLCl]PF6 (M = Ru, Rh, Ir) have been synthesized in this study. All these complexes were fully characterized with the help of FT-IR, UV-Vis, mass and NMR spectroscopy. The molecular structures of representative complexes (1, 2, 7 and 8) were established by single crystal X-ray diffraction study. The molecular structures of the complexes revealed typical piano stool geometry around the metal center in which the ligand acts as NN' donor chelating ligand. In the case of complexes (1-3), the ligand coordinates to the metal by using both the pyridine nitrogen atoms forming a six membered metallocycle whereas in complexes (4-9) one hydrazone nitrogen atom and one pyridine nitrogen atom coordinates to the metal ion forming a five membered metallocycle. These compounds were evaluated for their in vitro antibacterial activity by agar well diffusion method against two Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa, and two Gram-positive bacteria Staphylococcus aureus, Bacillus thuringiensis. Results show that all the complexes inhibit the growth of bacteria.

  DOI：

  10.1016/j.ica.2018.09.067
• 作为产物：
  描述：

  2-苯甲酰吡啶 、 2,4-二硝基苯肼 以 甲醇 为溶剂， 反应 6.0h， 以0.75 g的产率得到2-benzoylpyridine 2,4-dinitrophenylhydrazone
  参考文献：
  名称：

  Dutta, R. L.; Kuntala, D. E., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1988, vol. 27, # 2, p. 133 - 136

  摘要：

  DOI：

文献信息

• Synthesis and characterization of a homologous series of mononuclear palladium complexes containing different cyclometalated ligands
  作者：Iolinda Aiello、Alessandra Crispini、Mauro Ghedini、Massimo La Deda、Francesco Barigelletti

  DOI：10.1016/s0020-1693(00)00216-4

  日期：2000.10

  New mononuclear palladium(II) complexes formed by with 2-hydroxy-4-( n -hexyloxybenzylidene)-4′- n -hexyaniline ( HL ) and 2-phenylpyridine ( I ), benzo[h]quinoline ( II ), azobenzene ( III ), 2-benzoylpyridine ( IV ) or phenyl-2-pyridylketone-2,4-dinitrophenylhydrazone ( V ) have been synthesized and characterized by analytical and spectroscopic methods and the single-crystal structures of [(IVa)Pd(L)]

  摘要由2-羟基-4-（正己氧基苄基）-4'-正己基苯胺（HL）和2-苯基吡啶（I），苯并[h]喹啉（II），偶氮苯形成的新型单核钯（II）配合物（III）合成了2-苯甲酰基吡啶（IV）或苯基-2-吡啶基酮-2,4-二硝基苯基hydr（V）并通过分析和光谱法表征了[（IVa）Pd（L） ]和[（Va）Pd（L）]已建立。光谱和衍射数据解释了分子结构，其中钯（II）中心是两个螯合环的一部分，两个螯合环涉及HL和一个I-V配体，后者形成五元N，C [（（Ia）PdL]，[ （IIa）Pd（L）]和[（IIIa）Pd（L）]}，六元N，C [（（IVa）Pd（L）]}）或六元N，N'[ （Va）Pd（L）]}金属环。[（IIIa）Pd（L）]和[（Va）Pd（L）]的电子光谱在495（e〜3×10 3 M -1 cm -1）和531 nm（e〜分别为2×10 4 M -1 cm -1），该结
• Beckmann Rearrangement of the Oximes of Phenyl 2-Pyridyl Ketone (2-Benzoylpyridine)
  作者：Ernest H. Huntress、Henry C. Walter

  DOI：10.1021/ja01191a046

  日期：1948.11
• Antimicrobial selectivity of ruthenium, rhodium, and iridium half sandwich complexes containing phenyl hydrazone Schiff base ligands towards B. thuringiensis and P. aeruginosa bacteria
  作者：Agreeda Lapasam、Lincoln Dkhar、Nidhi Joshi、Krishna Mohan Poluri、Mohan Rao Kollipara

  DOI：10.1016/j.ica.2018.09.067

  日期：2019.1

  A series of new hydrazone mononuclear complexes of the type [(arene)MLCl]PF6 (M = Ru, Rh, Ir) have been synthesized in this study. All these complexes were fully characterized with the help of FT-IR, UV-Vis, mass and NMR spectroscopy. The molecular structures of representative complexes (1, 2, 7 and 8) were established by single crystal X-ray diffraction study. The molecular structures of the complexes revealed typical piano stool geometry around the metal center in which the ligand acts as NN' donor chelating ligand. In the case of complexes (1-3), the ligand coordinates to the metal by using both the pyridine nitrogen atoms forming a six membered metallocycle whereas in complexes (4-9) one hydrazone nitrogen atom and one pyridine nitrogen atom coordinates to the metal ion forming a five membered metallocycle. These compounds were evaluated for their in vitro antibacterial activity by agar well diffusion method against two Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa, and two Gram-positive bacteria Staphylococcus aureus, Bacillus thuringiensis. Results show that all the complexes inhibit the growth of bacteria.
• Dutta, R. L.; Kuntala, D. E., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1988, vol. 27, # 2, p. 133 - 136
  作者：Dutta, R. L.、Kuntala, D. E.

  DOI：——

  日期：——