(2-methyl-1-phenyl-but-3-enyl)-phenyl-amine | 80188-13-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2-methyl-1-phenyl-but-3-enyl)-phenyl-amine
• 英文别名: 2-methyl-N,1-diphenyl-3-butenylamine；N-(2-methyl-1-phenyl-3-butenyl)phenylamine；N-(2-methyl-1-phenylbut-3-enyl)aniline
• CAS: 80188-13-2
• 化学式: C₁₇H₁₉N
• 分子量: 237.345
• InChiKey: VROBUTOJHXGGGT-UHFFFAOYSA-N

物化性质

• 沸点：
  357.1±21.0 °C(Predicted)
• 密度：
  1.023±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 水 作用下， 以 乙醚 为溶剂， 反应 1.0h， 以70%的产率得到(2-methyl-1-phenyl-but-3-enyl)-phenyl-amine
  参考文献：
  名称：

  Reaction of titanocene allyls

  摘要：

  DOI：

  10.1016/s0022-328x(00)93174-7

文献信息

• Titanium-promoted allyl transfer to carbon monoxide and other unsaturated molecules
  作者：Bert Klei、Jan H. Teuben、Henk J. Liefde de Meijer

  DOI：10.1039/c39810000342

  日期：——

  Carbonylation of Cp2Ti-(π-allyl) yields Cp2Ti(CO)2 and triallylmethanol; reactions of Cp2Ti-(π-allyl) and Cp2Ti-(π-1-methylallyl) with other ligands proceed via insertion or allyl-elimination pathways.

  Cp 2 Ti-（π-烯丙基）的羰基化生成Cp 2 Ti（CO）2和三烯丙基乙醇；Cp 2 Ti-（π-烯丙基）和Cp 2 Ti-（π - 1-甲基烯丙基）与其他配体的反应通过插入或烯丙基消除途径进行。
• Generation of Prenylhafnium and α-Selective Addition to Imines
  作者：Ikuya Shibata、Shinji Miyamoto、Shinji Tsunoi、Kazuya Sakamoto、Akio Baba

  DOI：10.1002/ejoc.200900445

  日期：2009.7

  Allylhafnium compounds were generated by transmetalation between allyl-SnBu3 and HfCl4 in EtCN. A highly α-selective addition reaction of prenyltributyltin to imines was observed. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

  烯丙基铪化合物是通过烯丙基-SnBu3 和 HfCl4 在 EtCN 中的金属转移生成的。观察到异戊二烯三丁基锡与亚胺的高度α-选择性加成反应。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
• Generation of Allylic Indium by Hydroindation of 1,3-Dienes and One-Pot Reaction with Carbonyl Compounds
  作者：Naoki Hayashi、Hiroyuki Honda、Makoto Yasuda、Ikuya Shibata、Akio Baba

  DOI：10.1021/ol061797n

  日期：2006.9.1

  A hydroindation of 1,3-dienes by dichloroindium hydride (HInCl2) generates allylic indiums that react with carbonyl or imine moieties in a one-pot treatment. The former reaction proceeds in a radical manner, and the latter is ionic allylation. Moreover, both reactions require no additives such as radical initiators, Lewis acids, or transition metal catalysts.

  通过二氯氢化铟（HInCl2）对1,3-二烯进行加氢精制会生成烯丙基铟，它们在一键处理中会与羰基或亚胺基反应。前者以自由基方式进行，后者是离子烯丙基化。而且，两个反应都不需要添加剂，例如自由基引发剂，路易斯酸或过渡金属催化剂。
• Nickel-catalyzed dimerization coupling reactions of vinyl Grignard reagents with 3, 4-membered cyclic ethers and chlorosilanes
  作者：Yuuki Fujii、Jun Terao、Hiroyasu Watabe、Hiroyuki Watanabe、Nobuaki Kambe

  DOI：10.1016/j.tet.2007.04.013

  日期：2007.7

  Vinyl Grignard reagents reacted with cyclic ethers in the presence of a nickel catalyst giving rise to 2:1 coupling products 1 regioselectively. When chlorosilanes were used instead of cyclic ethers, 2:2 component coupling products 6 were obtained. A plausible reaction pathway via 1,3-butadiene–nickel complex and (2-butene-1,4-diyl)magnesium was proposed.

  在镍催化剂的存在下，乙烯基格氏试剂与环醚反应，从而选择性地产生2：1的偶合产物1。当使用氯硅烷代替环醚时，获得了2：2的组分偶联产物6。提出了通过1,3-丁二烯-镍络合物和（2-丁烯-1,4-二基）镁的合理反应途径。
• Heterogeneous Single-Atom Zinc on Nitrogen-Doped Carbon Catalyzed Electrochemical Allylation of Imines
  作者：Ryusuke Masuda、Tomohiro Yasukawa、Yasuhiro Yamashita、Tei Maki、Tomoko Yoshida、Shu̅ Kobayashi

  DOI：10.1021/jacs.3c03674

  日期：2023.6.7

  for carbon–carbon bond formation; however, consumption of stoichiometric amounts of metals is problematic. We developed electrochemical allylation reactions of imines catalyzed by nitrogen-doped carbon-supported single-atom zinc, which were fixed on a cathode to afford a range of homoallylic amines efficiently. The system could suppress generation of metallic waste, and the catalyst electrode showed

  有机金属试剂对碳-碳键的形成是有效的；然而，化学计量金属的消耗是有问题的。我们开发了由氮掺杂碳负载单原子锌催化的亚胺电化学烯丙基化反应，将其固定在阴极上以有效地提供一系列同型烯丙基胺。该系统可以抑制金属废物的产生，并且催化剂电极在活性和坚固性方面显示出优于散装锌的优势。还成功地进行了电化学流动反应，以最少的废物量连续生产高烯丙基胺。