Hex-(Z)-ylidene-(1-phenyl-ethyl)-amine | 478932-96-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Hex-(Z)-ylidene-(1-phenyl-ethyl)-amine
• 英文别名: N-(1-phenylethyl)hexan-1-imine
• CAS: 478932-96-6
• 化学式: C₁₄H₂₁N
• 分子量: 203.327
• InChiKey: ACGJRYGDRYZQCD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  异烟酸 、 allyl isocyanide 、 Hex-(Z)-ylidene-(1-phenyl-ethyl)-amine 以 甲醇 为溶剂， 生成 N-[1-oxo-1-(prop-2-enylamino)heptan-2-yl]-N-(1-phenylethyl)pyridine-4-carboxamide
  参考文献：
  名称：

  Novel anti-tuberculosis agents from MCR libraries

  摘要：

  Structure-based design of libraries of multi-component reaction products yields novel potent anti-tuberculosis compounds. Synthesis and preliminary biological results are presented. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.04.066
• 作为产物：
  描述：

  正己醛 、 α-苯乙胺 反应 4.0h， 生成 Hex-(Z)-ylidene-(1-phenyl-ethyl)-amine
  参考文献：
  名称：

  Novel anti-tuberculosis agents from MCR libraries

  摘要：

  Structure-based design of libraries of multi-component reaction products yields novel potent anti-tuberculosis compounds. Synthesis and preliminary biological results are presented. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.04.066

文献信息

• Anti-Markovnikov Hydroamination of Terminal Alkynes
  作者：Annegret Tillack、Ivette Garcia Castro、Christian G. Hartung、Matthias Beller

  DOI：10.1002/1521-3773(20020715)41:14<2541::aid-anie2541>3.0.co;2-7

  日期：2002.7.15
• Novel anti-tuberculosis agents from MCR libraries
  作者：Alexander Dömling、Sepp Achatz、Barbara Beck

  DOI：10.1016/j.bmcl.2007.04.066

  日期：2007.10

  Structure-based design of libraries of multi-component reaction products yields novel potent anti-tuberculosis compounds. Synthesis and preliminary biological results are presented. (C) 2007 Elsevier Ltd. All rights reserved.