2-deoxy-D-gluc-5-ulosonic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: 2-deoxy-D-gluc-5-ulosonic acid
• 英文别名: (3R,4S)-3,4,6-trihydroxy-5-oxohexanoic acid
• 化学式: C₆H₁₀O₆
• 分子量: 178.14
• InChiKey: UCYNJPYWOSFBAT-CVYQJGLWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.4
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  115
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• METHODS OF DISRUPTING A BIOFILM AND/OR PREVENTING FORMATION OF SAME
  申请人：Yeda Research and Development Co. Ltd

  公开号：EP3773907A1

  公开（公告）日：2021-02-17
• Pathway Analysis of Cell Culture Phenotypes and Uses Thereof
  申请人：Melville Mark

  公开号：US20090186358A1

  公开（公告）日：2009-07-23

  The present invention provides methods for systematically identifying genes, proteins and/or related pathways that regulate or indicative of cell phenotypes. The present invention further provides methods for manipulating the identified genes, proteins and/or pathways to engineer improved cell lines and/or to evaluate or select cell lines with desirable phenotypes.
• [EN] METHODS OF DISRUPTING A BIOFILM AND/OR PREVENTING FORMATION OF SAME<br/>[FR] PROCÉDÉS POUR PERTURBER UN BIOFILM ET/OU EMPÊCHER LA FORMATION DE CELUI-CI
  申请人：YEDA RES & DEV

  公开号：WO2019186570A1

  公开（公告）日：2019-10-03

  Methods of disrupting a biofilm and/or preventing formation of a biofilm are provided. Accordingly there is provided a method of reducing or preventing formation of a biofilm and/or disrupting a biofilm comprising contacting a biofilm-producing microorganism with a carbonic anhydrase inhibitor; a urease inhibitor; a Ca2+ ATPase inhibitor; a tip activator; and/or a myoinositol catabolism pathway activator. Also provided are articles of manufacture and methods of treating a medical condition in which disrupting a biofilm and/or preventing formation of same is beneficial and methods of predicting or increasing sensitivity to an anti-microbial agent.