Hypoxanthine, 9-(cis-3-(hydroxymethyl)cyclopentyl)- | 120330-37-2

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 核苷和核苷酸类似物
• 英文名称: Hypoxanthine, 9-(cis-3-(hydroxymethyl)cyclopentyl)-
• 英文别名: 9-[(1S,3R)-3-(hydroxymethyl)cyclopentyl]-1H-purin-6-one
• CAS: 120330-37-2
• 化学式: C₁₁H₁₄N₄O₂
• 分子量: 234.25
• InChiKey: OWBYMOPAAVGKEM-SFYZADRCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  79.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Carboxylic purine nucleosides, their production and use
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP0236935A2

  公开（公告）日：1987-09-16

  A compound of the formula: wherein R is a hydroxyl group which may be protected and Y is a purine base which may be protected, and the salts threof; which is useful as an antiviral agent.

  一种式如下的化合物 其中 R 是可被保护的羟基，Y 是可被保护的嘌呤基及其盐类；该化合物可用作抗病毒剂。
• Cosmetic composition and the use thereof for regulating skin quality
  申请人：AchromaZ Pte. Ltd.

  公开号：US11123279B2

  公开（公告）日：2021-09-21

  The present invention relates to cosmetic or personal care compositions comprising two or more compounds, each compound containing an allylic or partially allylic carbonylsubstructure having the following structure I: wherein Y is a second substructure immediately adjacent to the allylic or partially allyliccarbonyl substructure and is selected from one of the following groups consisting of (i) hydroxyl-based group including —OH or —C(═)—(OH); (ii)carbonyl-based group including —C(═)—C (═O)—CH3; (iii) N ether group, —O—; (iv) sultam group, —N(H)—S(═O)2—; (v) lactam group, —N(H)—C(═O)—; (vi) apolar group including cyclic structures based on menthol or carotenoids; (vii) secondary aldimine containing group including —N(H)—C(NH2)═N— or —N(H)—C(H)═N—; (viii) amine group, —NH2; (ix) secondary amine-based group, —N(H)—; and (x) amide-based group including —N(H)—C(═O)— or —N(H)—C(═O)—N(H)—, their derivatives, isomers, salts and/or combination thereof; and a cosmetically acceptable vehicle.

  本发明涉及由两种或两种以上化合物组成的化妆品或个人护理组合物，每种化合物含有具有以下结构I的烯丙基或部分烯丙基羰基亚结构：其中 Y 是紧邻烯丙基或部分烯丙基羰基亚结构的第二个亚结构，选自下列基团之一 (i) 羟基基团，包括-OH 或-C(═)-(OH)；(ii) 羰基基团，包括-C(═)-C(═O)-CH3； (iii) N 醚基团，-O-； (iv) 苏坦基团，-N(H)-S(═O)2-； (v) 内酰胺基团，-N(H)-C(═O)-；(v) 内酰胺基团，-N(H)-C(═O)-； (vi) 极性基团，包括基于薄荷醇或类胡萝卜素的环状结构； (vii) 含仲醛亚胺的基团，包括-N(H)-C(NH2)═N-或-N(H)-C(H)═N-； (viii) 氨基基团，-NH2；(x) 酰胺基团，包括-N(H)-C(═O)-或-N(H)-C(═O)-N(H)-，它们的衍生物、异构体、盐和/或它们的组合；以及化妆品可接受的载体。
• A Cosmetic Composition and the Use Thereof for Regulating Skin Quality
  申请人：AchromaZ Pte. Ltd.

  公开号：US20190021974A1

  公开（公告）日：2019-01-24

  The present invention relates to cosmetic or personal care compositions comprising two or more compounds, each compound containing an allylic or partially allylic carbonyl substructure having the following structure I: wherein Y is a second substructure immediately adjacent to the allylic or partially allyliccarbonyl substructure and is selected from one of the following groups consisting of (i) hydroxyl-based group including —OH or —C(═)—(OH); (ii) carbonyl-based group including —C(═)—C (═O)—CH 3 ; (iii) ether group, —O—; (iv) sultam group, —N(H)—S(═O) 2 —; (v) lactam group, —N(H)—C(═O)—; (vi) apolar group including cyclic structures based on menthol or carotenoids; (vii) secondary aldimine containing group including —N(H)—C(NH 2 )═N— or —N(H)—C(H)═N—; (viii) amine group, —NH 2 ; (ix) secondary amine-based group, —N(H)—; and (x) amide-based group including —N(H)—C(═O)— or —N(H)—C(═O)—N(H)—, their derivatives, isomers, salts and/or combination thereof; and a cosmetically acceptable vehicle.
• US4916224A
  申请人：——

  公开号：US4916224A

  公开（公告）日：1990-04-10
• US4968674A
  申请人：——

  公开号：US4968674A

  公开（公告）日：1990-11-06