Serotonin, alpha-methylaminocarbonyl-

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: Serotonin, alpha-methylaminocarbonyl-
• 英文别名: 2-amino-3-(5-hydroxy-1H-indol-3-yl)-N-methylpropanamide
• 化学式: C₁₂H₁₅N₃O₂
• 分子量: 233.27
• InChiKey: QNCCNYVRKCGBEL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  91.1
• 氢给体数：
  4
• 氢受体数：
  3

文献信息

• COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF MULTIPLE SCLEROSIS
  申请人：CELLIX BIO PRIVATE LIMITED

  公开号：EP3201168B1

  公开（公告）日：2020-03-18
• USE OF BIOLOGICAL RNA SCAFFOLDS WITH IN VITRO SELECTION TO GENERATE ROBUST SMALL MOLECULE BINDING APTAMERS FOR GENETICALLY ENCODABLE BIOSENSORS
  申请人：The Regents of the University of Colorado, a body corporate

  公开号：EP3551755A1

  公开（公告）日：2019-10-16
• [EN] USE OF BIOLOGICAL RNA SCAFFOLDS WITH IN VITRO SELECTION TO GENERATE ROBUST SMALL MOLECULE BINDING APTAMERS FOR GENETICALLY ENCODABLE BIOSENSORS<br/>[FR] UTILISATION D'ÉCHAFAUDAGES D'ARN BIOLOGIQUES AVEC SÉLECTION IN VITRO AFIN DE GÉNÉRER DES APTAMÈRES DE LIAISON DE PETITES MOLÉCULES ROBUSTES POUR DES BIOCAPTEURS POUVANT ÊTRE CODÉS GÉNÉTIQUEMENT
  申请人：UNIV COLORADO REGENTS

  公开号：WO2018111745A1

  公开（公告）日：2018-06-21

  Provided herein are libraries of scaffolds derived from riboswitches and small ribozymes and their methods of use. The scaffolds of the invention yield aptamers that are easily identified and characterized by virtue of the structural scaffold. The nature of the scaffold predisposes these RNAs for coupling to readout domains to engineer biosensors that function in vitro and in vivo. Biosensors, synthetic RNA agents and synthetic DNA agents, and their methods of use, are also provided.