(2-bromopyridin-3-yl)phenylmethylbromide | 161987-57-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (2-bromopyridin-3-yl)phenylmethylbromide
• 英文别名: 2-Bromo-3-[bromo(phenyl)methyl]pyridine；2-bromo-3-[bromo(phenyl)methyl]pyridine
• CAS: 161987-57-1
• 化学式: C₁₂H₉Br₂N
• 分子量: 327.018
• InChiKey: BUIWKGPECDMCBV-UHFFFAOYSA-N

物化性质

• 沸点：
  387.7±37.0 °C(Predicted)
• 密度：
  1.701±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (2-bromopyridin-3-yl)phenylmethylbromide 在 air 作用下， 生成
  参考文献：
  名称：

  Synthesis of heterocyclic compounds containing three contiguous hydrogen bonding sites in all possible arrangements

  摘要：

  The synthesis of compounds containing three contiguous hydrogen bond sites is reported. There are six ways of arranging three adjacent hydrogen bond donor (D) and acceptor (A) sites. General synthetic routes to heterocyclic compounds with each arrangement is reported.

  DOI：

  10.1016/0040-4020(94)00922-h
• 作为产物：
  描述：

  (2-bromopyridin-3-yl)(phenyl)methanol 在 氢溴酸 作用下， 以 溶剂黄146 为溶剂， 反应 16.0h， 以74%的产率得到(2-bromopyridin-3-yl)phenylmethylbromide
  参考文献：
  名称：

  Synthesis of heterocyclic compounds containing three contiguous hydrogen bonding sites in all possible arrangements

  摘要：

  The synthesis of compounds containing three contiguous hydrogen bond sites is reported. There are six ways of arranging three adjacent hydrogen bond donor (D) and acceptor (A) sites. General synthetic routes to heterocyclic compounds with each arrangement is reported.

  DOI：

  10.1016/0040-4020(94)00922-h

文献信息

• Synthesis of heterocyclic compounds containing three contiguous hydrogen bonding sites in all possible arrangements
  作者：Thomas J. Murray、Steven C. Zimmerman、Sergei V. Kolotuchin

  DOI：10.1016/0040-4020(94)00922-h

  日期：1995.1

  The synthesis of compounds containing three contiguous hydrogen bond sites is reported. There are six ways of arranging three adjacent hydrogen bond donor (D) and acceptor (A) sites. General synthetic routes to heterocyclic compounds with each arrangement is reported.