ethyl 6-bromo-5-hydroxy-1-methyl-2-[(phenylsulfonyl)methyl]-1H-indole-3-carboxylate | 172041-15-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: ethyl 6-bromo-5-hydroxy-1-methyl-2-[(phenylsulfonyl)methyl]-1H-indole-3-carboxylate
• 英文别名: ethyl 2-(benzenesulfonylmethyl)-6-bromo-5-hydroxy-1-methylindole-3-carboxylate
• CAS: 172041-15-5
• 化学式: C₁₉H₁₈BrNO₅S
• mdl: MFCD00359337
• 分子量: 452.3
• InChiKey: NNMHPRLYFSJAGD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  94
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• ANTIDIABETIC PHARMACEUTICAL COMPOSITION
  申请人：Zakrytoe Aktsionernoe Obschestvo "Masterklon"

  公开号：EP2204173B1

  公开（公告）日：2013-07-03
• Medicinal Agent For Treating Viral Infections
  申请人：Leneva Irina Anatolievna

  公开号：US20090326037A1

  公开（公告）日：2009-12-31

  The invention relates to medicine, in particular to searching and developing novel medicinal agents for treating and preventing viral infections, mainly influenza viruses. The aim of said invention is to develop more efficient and low toxic medicinal agents by combining arbidol and the analogs thereof with a preparation exhibiting another mechanism of action. Said combinations enhances the efficiency of the preparation small doses and makes it possible to reduce the probability of side effects and appearance of virus resistant strain by reducing the dose. The result is attained by the combined use of arbidol and the analogies thereof with at least one type of preparation selected from the following group of antiviral preparations: ribavirin, zanamivirin, oseltavirin, peramirin, amantadin or remantadin.
• US8247407B2
  申请人：——

  公开号：US8247407B2

  公开（公告）日：2012-08-21