20-mercapto-eicosane-1-ol | 149340-92-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醇
• 英文名称: 20-mercapto-eicosane-1-ol
• 英文别名: 20-Sulfanylicosan-1-ol
• CAS: 149340-92-1
• 化学式: C₂₀H₄₂OS
• 分子量: 330.619
• InChiKey: KACKDNJZQRLAIQ-UHFFFAOYSA-N

物化性质

• 沸点：
  438.9±18.0 °C(Predicted)
• 密度：
  0.892±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  22
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  20-mercapto-eicosane-1-ol 在 碘 作用下， 以 甲醇 为溶剂， 生成 bis(20-hydroxyeicosyl)disulfide
  参考文献：
  名称：

  Charge-Transfer Mechanism for Cytochrome c Adsorbed on Nanometer Thick Films. Distinguishing Frictional Control from Conformational Gating

  摘要：

  Using nanometer thick tunneling barriers with specifically attached cytochrome c, the electron-transfer rate constant was studied as a function of the SAM composition (alkane versus terthiophene), the omega-terminating group type (pyridine, imidazole, nitrile), and the solution viscosity. At large electrode-reactant separations, the pyridine terminated alkanethiols exhibit an exponential decline of the rate constant with increasing electron-transfer distance. At short separations, a plateau behavior, analogous to systems involving -COOH terminal groups to which cytochrome c can be attached electrostatically, is observed. The dependence of the rate constant in the plateau region on system properties is investigated. The rate constant is insensitive to the mode of attachment to the surface but displays a significant viscosity dependence, change with spacer composition (alkane versus terthiophene), and nature of the solvent (H2O versus D2O). Based on these findings and others, the conclusion is drawn that the charge-transfer rate constant at short distance is determined by polarization relaxation processes in the structure, rather than the electron tunneling probability or large-amplitude conformational rearrangement (gating). The transition in reaction mechanism with distance reflects a gradual transition between the tunneling and frictional mechanisms. This conclusion is consistent with data from a number of other sources as well.

  DOI：

  10.1021/ja034719t
• 作为产物：
  描述：

  1,20-二十烷二醇 在 溴 、 肼 作用下， 以 乙醇 、 Petroleum ether 为溶剂， 生成 20-mercapto-eicosane-1-ol
  参考文献：
  名称：

  Electrochemistry of Cytochromecat a Lipid Langmuir Blodgett Monolayer Electrode

  摘要：

  研究发现，细胞色素 c 在由 20-巯基-1-二十烷醇/二油酰-L-α-磷脂酰胆碱（摩尔比为 1/20）的 Langmuir-Blodgett 单层修饰的金电极上发生电子转移反应。此外，还考察了单层的稳定性以及细胞色素 c 在单层上的吸附行为。

  DOI：

  10.1246/cl.1993.1021

文献信息

• Thermoplastic resin composition
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0513812A2

  公开（公告）日：1992-11-19

  A thermoplastic resin composition is disclosed, comprising (A) from 10 to 90% by weight of a hydroxy-substituted poly(phenylene ether) ether resin comprising p repeating units represented by formula (I): wherein m represents an integer of from 1 to 4; n represents an integer of from 0 to 3; the sum of m and n is not greater than 4; J represents (HO)a-R1-S-R2-, wherein a represents an integer of from 1 to 6; R' represents a halogen-substituted or unsubstituted polyvalent aliphatic hydrocarbon group having from 1 to 20 carbon atoms which may contain an oxygen atom in the carbon chain thereof or a halogen-substituted or unsubstituted polyvalent aromatic hydrocarbon group having from 1 to 20 carbon atoms; and R2 represents an alkylene group having from 2 to 20 carbon atoms; when m is 2 or more, the plural J groups may be the same or different; K represents a halogen atom, a primary or secondary alkyl group having from 1 to 20 carbon atoms, an alkenyl group having from 2 to 20 carbon atoms, a phenyl group, an aminoalkyl group having from 1 to 20 carbon atoms, a haloalkyl group having from 1 to 20 carbon atoms, an alkoxy group having from 1 to 20 carbon atoms, or a halohydrocarbonoxy group having from 1 to 20 carbon atoms; and when n is 2 or more, the plural K groups may be the same or different, and q repeating units represented by formula (II): wherein Q1, Q2, Q3, and Q4 each represent a hydrogen atom, a halogen atom, a primary or secondary alkyl group having from 1 to 20 carbon atoms, an alkenyl group having from 2 to 20 carbon atoms, a phenyl group, an aminoalkyl group having from 1 to 20 carbon atoms, a haloalkyl group having from 1 to 20 carbon atoms, an alkoxy group having from 1 to 20 carbon atoms, or a halohydrocarbonoxy group having from 1 to 20 carbon atoms, with p and q satisfying formulae: and (B) from 10 to 90% by weight of a thermoplastic resin selected from a saturated polyester resin and a polyamide resin. The composition is excellent in moldability and provides molded articles excellent in impact strength, heat resistance, and hue.

  本发明公开了一种热塑性树脂组合物，其中包括 (A) 10% 至 90% （按重量计）的羟基取代的聚（亚苯基醚）醚树脂，该树脂包含由式 (I) 代表的 p 个重复单元： 其中 m 代表 1 至 4 的整数；n 代表 0 至 3 的整数；m 和 n 之和不大于 4；J 代表 (HO)a-R1-S-R2-，其中 a 代表 1 至 6 的整数；R' 代表具有 1 至 20 个碳原子的卤素取代或未取代的多价脂族烃基，其碳链中可含有一 个氧原子，或具有 1 至 20 个碳原子的卤素取代或未取代的多价芳族烃基；以及 R2 代表具有 2 至 20 个碳原子的亚烷基；当 m 为 2 或 2 个以上时，多个 J 基团可以相同或不同；K 代表卤素原子、具有 1 至 20 个碳原子的伯或仲烷基、具有 2 至 20 个碳原子的烯基、苯基、具有 1 至 20 个碳原子的氨基烷基、具有 1 至 20 个碳原子的卤代烷基、具有 1 至 20 个碳原子的烷氧基或具有 1 至 20 个碳原子的卤代烃氧基；当 n 为 2 或 2 个以上时，多个 K 基团可以相同或不同、 和 q 个由式 (II) 代表的重复单元： 其中 Q1、Q2、Q3 和 Q4 分别代表氢原子、卤素原子、具有 1 至 20 个碳原子的伯或仲烷基、具有 2 至 20 个碳原子的烯基、苯基、具有 1 至 20 个碳原子的氨基烷基、具有 1 至 20 个碳原子的卤代烷基、具有 1 至 20 个碳原子的烷氧基或具有 1 至 20 个碳原子的卤代烃氧基，p 和 q 满足式： 和 (B) 10%至 90%（按重量计）的热塑性树脂，选自饱和聚酯树脂和聚酰胺树脂。该组合物具有优异的可模塑性，可提供抗冲击强度、耐热性和色调优异的模塑制品。
• Polymer parts
  申请人：Sony DADC Austria AG

  公开号：EP2792471A1

  公开（公告）日：2014-10-22

  A method of producing a polymer part comprising the following steps: (a) incorporating a hydrophobic small molecule into the polymer before, during or after manufacture of the polymer part, the hydrophobic small molecule and the polymer being essentially inert to one another; and (b) annealing the polymer part to induce migration of the hydrophobic small molecules to a surface of the polymer part to provide that surface with a specified degree of hydrophobicity defined by the combination of the polymer and the hydrophobic small molecule; is described. Polymer parts made according to the method are also described.

  一种生产聚合物部件的方法，包括以下步骤：(a) 在制造聚合物部件之前、期间或之后，将疏水性小分子掺入聚合物中，疏水性小分子和聚合物基本上互为惰性；以及 (b) 对聚合物部件进行退火处理，促使疏水性小分子迁移到聚合物部件的表面，使该表面具有由聚合物和疏水性小分子的组合确定的特定疏水性。还描述了根据该方法制造的聚合物部件。
• GM3 functionalized nanoparticles
  申请人：TRUSTEES OF BOSTON UNIVERSITY

  公开号：US10004695B2

  公开（公告）日：2018-06-26

  Embodiments disclosed herein relates to ganglioside GM3-containing mixed lipids nanoparticles having an overall size between 60-100 nm, the making thereof and the uses. The nanoparticles selectively targeted to CD169+ expressing cells such as dendritic cells and macrophage. The nanoparticles are endocytosed by the CD169+ expressing cells.

  本文公开的实施方案涉及总尺寸在60-100纳米之间的含神经节苷脂GM3的混合脂质纳米颗粒、其制造方法和用途。该纳米颗粒可选择性地靶向 CD169+ 表达细胞，如树突状细胞和巨噬细胞。纳米颗粒可被 CD169+ 表达细胞内吞。
• Method of producing a polymer part and polymer part
  申请人：STRATEC CONSUMABLES GmbH

  公开号：US10611890B2

  公开（公告）日：2020-04-07

  A method of producing a polymer part comprising the following steps: (a) incorporating a hydrophobic small molecule into the polymer before, during or after manufacture of the polymer part, the hydrophobic small molecule and the polymer being essentially inert to one another; and (b) annealing the polymer part to induce migration of the hydrophobic small molecules to a surface of the polymer part to provide that surface with a specified degree of hydrophobicity defined by the combination of the polymer and the hydrophobic small molecule; is described. Polymer parts made according to the method are also described.

  一种生产聚合物部件的方法，包括以下步骤：(a) 在制造聚合物部件之前、期间或之后，将疏水性小分子掺入聚合物中，疏水性小分子和聚合物基本上互为惰性；以及 (b) 对聚合物部件进行退火处理，促使疏水性小分子迁移到聚合物部件的表面，使该表面具有由聚合物和疏水性小分子的组合确定的特定疏水性。还描述了根据该方法制造的聚合物部件。
• Polymer slides having hydrophobic small molecules
  申请人：STRATEC Consumables GmbH

  公开号：US10800895B2

  公开（公告）日：2020-10-13

  A plurality of polymer slides, each having a polymer part with a first polymer surface portion uncoated and a second surface portion coated with a metal. The first and second surface portions each have different surface coating properties and have respective first and second specified degrees of hydrophobicity which are different from each other. A hydrophobic small molecule is located in the polymer part of each polymer slide, and the hydrophobic small molecule and the polymer are essentially inert to one another. Adjacent polymer slides are arranged in a manner that the first polymer surface of one slide faces a metal coated second surface portion of another slide. The hydrophobic small molecule evaporates from said first polymer surface portion of the polymer part of one polymer slide onto the adjacent metal coated second surface portion of another polymer slide.

  多个聚合物载玻片，每个载玻片都有一个聚合物部分，第一聚合物表面部分没有涂层，第二表面部分涂有金属。第一和第二表面部分各自具有不同的表面涂层特性，并具有各自不同的第一和第二疏水性。疏水小分子位于每个聚合物载玻片的聚合物部分，疏水小分子和聚合物之间基本上是惰性的。相邻聚合物载玻片的排列方式是，一个载玻片的第一聚合物表面朝向另一个载玻片的第二表面金属涂层部分。疏水小分子从一个聚合物载玻片的聚合物部分的第一聚合物表面蒸发到相邻的另一个聚合物载玻片的涂有金属的第二表面部分上。