10,12-heneicosadiyn-1-ol | 260358-08-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 10,12-heneicosadiyn-1-ol
• 英文别名: Henicosa-10,12-diyn-1-ol
• CAS: 260358-08-5
• 化学式: C₂₁H₃₆O
• 分子量: 304.516
• InChiKey: WKIFOORMFAFPCY-UHFFFAOYSA-N

物化性质

• 沸点：
  437.7±18.0 °C(Predicted)
• 密度：
  0.897±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  22
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  10,12-heneicosadiyn-1-ol 在 吡啶 、 sodium hydrogensulfide 作用下， 以 乙醇 、 氯仿 为溶剂， 反应 19.0h， 生成 di(henicosa-10,12-diyn-1-yl) disulfide
  参考文献：
  名称：

  The synthesis of conjugated diacetylene monomers for the fabrication of polymerized monolayer assemblies

  摘要：

  Symmetrical disulfides containing conjugated diacetylene groups for use in forming polymerized self-assembled monolayers have been fabricated using common synthetic techniques. In contrast with previous reports, the proposed synthetic route does not require the use of hexamethylphosphoramide (HMPA) or the incorporation of an ester moiety near the surface attachment site. Overall yields of 20-30% are readily achieved for this four-step synthesis. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0040-4039(96)02262-9
• 作为产物：
  描述：

  1-癸炔 在 氢氧化钾 、 正丁基锂 、 盐酸羟胺 、 碘 、 乙胺 、 copper(l) chloride 作用下， 以 四氢呋喃 、 甲醇 、 正己烷 为溶剂， 反应 4.0h， 生成 10,12-heneicosadiyn-1-ol
  参考文献：
  名称：

  The synthesis of conjugated diacetylene monomers for the fabrication of polymerized monolayer assemblies

  摘要：

  Symmetrical disulfides containing conjugated diacetylene groups for use in forming polymerized self-assembled monolayers have been fabricated using common synthetic techniques. In contrast with previous reports, the proposed synthetic route does not require the use of hexamethylphosphoramide (HMPA) or the incorporation of an ester moiety near the surface attachment site. Overall yields of 20-30% are readily achieved for this four-step synthesis. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0040-4039(96)02262-9

文献信息

• The synthesis of conjugated diacetylene monomers for the fabrication of polymerized monolayer assemblies
  作者：Mark D. Mowery、Christine E. Evans

  DOI：10.1016/s0040-4039(96)02262-9

  日期：1997.1

  Symmetrical disulfides containing conjugated diacetylene groups for use in forming polymerized self-assembled monolayers have been fabricated using common synthetic techniques. In contrast with previous reports, the proposed synthetic route does not require the use of hexamethylphosphoramide (HMPA) or the incorporation of an ester moiety near the surface attachment site. Overall yields of 20-30% are readily achieved for this four-step synthesis. Copyright (C) 1996 Elsevier Science Ltd