Process for producing omega-9 highly unsaturated fatty acid and lipid containing the same
申请人:SUNTORY LIMITED
公开号:EP0825263A2
公开(公告)日:1998-02-25
The present invention discloses a process for producing lipid containing omega-9 highly unsaturated fatty acid by culturing in a medium a mutant strain obtained by mutation on a microorganism having the ability to produce arachidonic acid belonging to the genus Mortierella and so forth, in which Δ12 desaturation activity is decreased or lost, but at least one of Δ5 desaturation activity, Δ6 desaturation activity and chain length elongation activity is elevated. Moreover, the present invention also discloses a process for producing omega-9 highly unsaturated fatty acid by collecting omega-9 highly unsaturated fatty acid from the culture or lipid described above.
本发明公开了一种生产含有ω-9高度不饱和脂肪酸的脂质的工艺,其方法是在培养基中培养通过突变获得的突变菌株,该突变菌株具有生产花生四烯酸的能力,属于莫氏菌属等,其中Δ12去饱和活性降低或丧失,但Δ5去饱和活性、Δ6去饱和活性和链长伸长活性中的至少一种活性升高。此外,本发明还公开了一种生产ω-9 高度不饱和脂肪酸的工艺,即从上述培养物或脂质中收集ω-9 高度不饱和脂肪酸。