diethyl 2-(3,5-dimethyl-1H-pyrrol-2-yl)propanedioate | 1268460-64-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: diethyl 2-(3,5-dimethyl-1H-pyrrol-2-yl)propanedioate
• CAS: 1268460-64-5
• 化学式: C₁₃H₁₉NO₄
• 分子量: 253.298
• InChiKey: GBELLFYLAPTXFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  68.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2,4-二甲基吡咯 、 溴代丙二酸二乙酯 在 [Ru(bpy)2(dbpy)]Cl2. 、 4-甲氧基三苯胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以55%的产率得到diethyl 2-(3,5-dimethyl-1H-pyrrol-2-yl)propanedioate
  参考文献：
  名称：

  Highly Stable and Porous Cross-Linked Polymers for Efficient Photocatalysis

  摘要：

  Porous cross-linked polymers (PCPs) with phosphorescent [Ru(bpy)(3)](2+) and [Ir(ppy)(2)(bpy)](+) building blocks were obtained via octacarbonyldicobalt (Co-2-(CO)(8))-catalyzed alkyne trimerization reactions. The resultant Ru- and Ir-PCPs exhibited high porosity with specific surface areas of 1348 and 1547 m(2)/g, respectively. They are thermally stable at up to 350 C in air and do not dissolve or decompose in all solvents tested, including concentrated hydrochloric acid. The photoactive PCPs were shown to be highly effective, recyclable, and reusable heterogeneous photocatalysts for aza-Henry reactions, alpha-arylation of bromomalonate, and oxyamination of an aldehyde, with catalytic activities comparable to those of the homogeneous [Ru(bpy)(3)](2+) and [Ir(ppy)(2)(bpy)](+) photo catalysts. This work highlights the potential of developing photoactive PCPs as highly stable, molecularly tunable, and recyclable and reusable heterogeneous photocatalysts for a variety of important organic transformations.

  DOI：

  10.1021/ja109166b

文献信息

• Highly Stable and Porous Cross-Linked Polymers for Efficient Photocatalysis
  作者：Zhigang Xie、Cheng Wang、Kathryn E. deKrafft、Wenbin Lin

  DOI：10.1021/ja109166b

  日期：2011.2.23

  Porous cross-linked polymers (PCPs) with phosphorescent [Ru(bpy)(3)](2+) and [Ir(ppy)(2)(bpy)](+) building blocks were obtained via octacarbonyldicobalt (Co-2-(CO)(8))-catalyzed alkyne trimerization reactions. The resultant Ru- and Ir-PCPs exhibited high porosity with specific surface areas of 1348 and 1547 m(2)/g, respectively. They are thermally stable at up to 350 C in air and do not dissolve or decompose in all solvents tested, including concentrated hydrochloric acid. The photoactive PCPs were shown to be highly effective, recyclable, and reusable heterogeneous photocatalysts for aza-Henry reactions, alpha-arylation of bromomalonate, and oxyamination of an aldehyde, with catalytic activities comparable to those of the homogeneous [Ru(bpy)(3)](2+) and [Ir(ppy)(2)(bpy)](+) photo catalysts. This work highlights the potential of developing photoactive PCPs as highly stable, molecularly tunable, and recyclable and reusable heterogeneous photocatalysts for a variety of important organic transformations.