2-(3,6-dinitrocarbazol-9-yl)-N,N-diethylethanamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2-(3,6-dinitrocarbazol-9-yl)-N,N-diethylethanamine
• 化学式: C18H20N4O4
• mdl: MFCD01542971
• 分子量: 356.4
• InChiKey: GRXHSPDYFQLEAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  99.8
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• [EN] CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS<br/>[FR] COMPOSÉS CARBAZOLE ET UTILISATIONS THÉRAPEUTIQUES DESDITS COMPOSÉS
  申请人：CLEVELAND BIOLABS INC

  公开号：WO2010042445A1

  公开（公告）日：2010-04-15

  Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).

  本发明揭示了一般结构式(I)和(II)的化合物及其盐和水合物的使用作为治疗剂。可治疗的疾病和病况包括癌症、炎症性疾病和病况，以及免疫缺陷病。 (I), (II)。
• Carbazole Compounds and Therapeutic Uses of the Compounds
  申请人：Tucker John

  公开号：US20110305661A1

  公开（公告）日：2011-12-15

  Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases.

  本发明揭示了具有一般结构式（I）和（II）的化合物及其盐和水合物的使用作为治疗剂。可治疗的疾病和病况包括癌症、炎症性疾病和病况以及免疫缺陷病。
• CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS
  申请人：Incuron, LLC

  公开号：US20140303224A1

  公开（公告）日：2014-10-09

  Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).

  本发明揭示了通式（I）和（II）的化合物以及这些化合物和其盐和水合物的用途作为治疗剂。可治疗的疾病和状况包括癌症、炎症性疾病和状况以及免疫缺陷病。 (I)，(II)。
• INDUCING CELL DEATH BY INHIBITING ADAPTIVE HEAT SHOCK RESPONSE
  申请人：Incuron, Inc.

  公开号：EP2294186B1

  公开（公告）日：2019-10-09
• Carbazole compounds and therapeutic uses of the compounds
  申请人：INCURON, LLC

  公开号：EP2356093B1

  公开（公告）日：2013-01-09