3-Chloro-4-difluoromethoxy-benzo[d]isothiazole 1,1-dioxide | 936922-51-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 3-Chloro-4-difluoromethoxy-benzo[d]isothiazole 1,1-dioxide
• 英文别名: 3-chloro-4-(difluoromethoxy)-1,2-benzothiazole 1,1-dioxide
• CAS: 936922-51-9
• 化学式: C₈H₄ClF₂NO₃S
• 分子量: 267.64
• InChiKey: UBAIEQGFCVQEFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  64.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3-Chloro-4-difluoromethoxy-benzo[d]isothiazole 1,1-dioxide 、 二乙胺 在 氯化铵 、 二氯甲烷 、 水 、 magnesium sulfate 、 silica 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 49.0h， 以to afford 200 mg (0.66 mmol; 35% of theory) of the title compound的产率得到(4-Difluoromethoxy-1,1-dioxo-1H-1λ6-benzo[d]isothiazol-3-yl)-diethyl-amine
  参考文献：
  名称：

  Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives

  摘要：

  本发明涉及使用式(I)中变量n和R1至R6如描述中所定义的3-氨基-1,2-苯并异噻唑化合物的杀虫方法。本发明涉及用于对抗或控制昆虫、蜘蛛或线虫的方法，用于保护生长中的植物免受昆虫、蜘蛛或线虫的攻击或侵染的方法，以及用于保护种子免受土壤昆虫的侵害并保护幼苗的根和茎免受土壤和叶面昆虫的侵害的方法。

  公开号：

  US20090069317A1
• 作为产物：
  描述：

  4-difluoromethoxy-saccharine 在 氯化亚砜 、 N,N-二甲基甲酰胺 作用下， 以 1,4-二氧六环 为溶剂， 反应 29.0h， 生成 3-Chloro-4-difluoromethoxy-benzo[d]isothiazole 1,1-dioxide
  参考文献：
  名称：

  Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives

  摘要：

  该发明涉及使用式(I)中变量n和R1至R6如描述中定义的3-氨基-1,2-苯并异噻唑化合物的杀虫方法。该发明涉及用于对抗或控制昆虫、蜘蛛或线虫的方法，用于保护生长中的植物免受昆虫、蜘蛛或线虫的侵害或感染的方法，以及用于保护种子免受土壤昆虫和幼苗的根和茎免受土壤和叶面昆虫侵害的方法。

  公开号：

  US20090069317A1

文献信息

• 3-amino-1,2-benzisothiazole compounds for combating animal pest
  申请人：BASF SE

  公开号：US08017554B2

  公开（公告）日：2011-09-13

  The present invention relates to 3-amino-1,2-benzisothiazole compounds of formula I wherein R1, R2, R3, R4, R5 and n are defined in the description. The present invention relates to insecticidal compounds of formula I and to their isomeric imino derivatives, as well as to the enantiomers, diastereomers and salts thereof and to compositions comprising such compounds. The invention also relates to the use of the 3-amino-1,2-benzisothiazole compounds, of their salts or of compositions comprising them for combating animal pests. Furthermore the invention relates also to methods of applying such compounds.

  本发明涉及公式I的3-氨基-1,2-苯并异噻唑化合物，其中R1、R2、R3、R4、R5和n在说明中有定义。本发明涉及公式I的杀虫化合物及其异构亚胺衍生物，以及其对映体，对映异构体和盐以及包含这些化合物的组合物。本发明还涉及使用3-氨基-1,2-苯并异噻唑化合物，其盐或包含它们的组合物来对抗动物害虫的用途。此外，本发明还涉及应用这些化合物的方法。
• 3-Amino-1,2-benzisothiazole Compounds for Combating Animal Pest
  申请人：Pohlman Matthias

  公开号：US20100167922A1

  公开（公告）日：2010-07-01

  The present invention relates to 3-amino-1,2-benzisothiazole compounds of formula I wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are defined in the description. The present invention relates to insecticidal compounds of formula I and to their isomeric imino derivatives, as well as to the enantiomers, diastereomers and salts thereof and to compositions comprising such compounds. The invention also relates to the use of the 3-amino-1,2-benzisothiazole compounds, of their salts or of compositions comprising them for combating animal pests. Furthermore the invention relates also to methods of applying such compounds.

  本发明涉及式I的3-氨基-1,2-苯并异噻唑化合物，其中R1、R2、R3、R4、R5和n在说明书中定义。本发明涉及式I的杀虫化合物及其同分异构体、对映异构体和盐，以及含有这些化合物的组合物。本发明还涉及使用3-氨基-1,2-苯并异噻唑化合物、其盐或含有它们的组合物来对抗动物害虫的用途。此外，本发明还涉及应用这些化合物的方法。
• WO2007/113119
  申请人：——

  公开号：——

  公开（公告）日：——
• WO2008/90048
  申请人：——

  公开号：——

  公开（公告）日：——
• 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II
  申请人：von Deyn Wolfgang

  公开号：US20100009848A1

  公开（公告）日：2010-01-14

  The invention provides 3-amino-1,2-benzisothiazole compounds of formula (I) wherein n, R 1 , R 2 , R 3 , R 4 and A are defined as in the description. The invention provides further agricultural compositions comprising an amount of at least one compound of the formula (I) or an enantiomer, diastereomer or salt thereof; the use of a compound of formula (I) or an enantiomer, diastereomer or salt thereof for combating animal pests; a method of combating animal pests which comprises contacting the animal pests, their habit, breeding ground, food supply, plant, seed, soil, area, material or environment in which the animal pests are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from animal attack or infestation with a pesticidally effective amount of at least one compound of the formula (I) or an enantiomer, diastereomer or salt thereof; a method for protecting crops from attack or infestation by animal pests, which comprises contacting a crop with a pesticidally effective amount of at least one compound of the formula (I) or an enantiomer, diastereomer or salt thereof; a method for the protection of seeds from soil insects and of the seedlings' roots and shoots from soil and foliar insects comprising contacting the seeds before sowing and/or after pregermination with at least one compound of the formula (I), or the enantiomers, diastereomers or salts thereof; and seeds comprising a compound of the formula I or an enantiomer, diastereomer or salt thereof.